Gene Information

Name : CD630_18560 (CD630_18560)
Accession : YP_001088362.1
Strain : Clostridium difficile 630
Genome accession: NC_009089
Putative virulence/resistance : Virulence
Product : hydrolase
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG3451
EC number : -
Position : 2145240 - 2147669 bp
Length : 2430 bp
Strand : +
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12568329, 12568327,17650959, 11157942,11073898, 8863741; Product type pe : putative enzyme

DNA sequence :
TTGAACAAAAAAAGAAAGATTCAGCAGCTAAAGTTAGAACAAAACAAAAAGAAGTTAAGAAGTCAAAGACAGGACTTAAA
GCAAAATAAGGGAAAATCTAAAAAAGATAAAGGCGGGCTACTTGACCTTATCTTTAGGAAAGAACCAAAAAGATATACTG
TTGAAGATACCATTCCCTACCTTAGACTATTAAAAAGTGGGATATGTCAGATTGATGAAAATCATTTTAATAAGAGTATC
GCCTTTGAGGATATAAACTATCAGCTTGCTTTAGAAGAAGATAGGGATTTGATTTTTAATCAGTTTGCAAACTTTCTTAA
TTCCTTTGATCCAAGTATAAGCATAGAGTTTTCATATATCAATCAGCTTGGTAGAAATGAAGAAATGAAATCGGCAATTC
AAATACCGGATAAAGGAGATGGTTTTGACGATATACGTCTTGAGTTTCGAGAAATGCTTAAAAGCCAGATTGTAAAAGGA
AATAACGGACTGAAAAAATCAAAATATGTAACTTTTACAGTAGAAGCGGATAATTTAGAACAAGCAACATCAAAACTGGA
AAGAATGGAGATAGATATATTATCAAGCTTTAAAAGTATGGGAGTAAGAGCAGAAAGCCTTAACGGAGAGGAAAGGCTAA
AGATACTTCATGATGTTTTAAATCCGAATAAGACCTTTGAATTTTCATATAAGGACTTAAAGAAAAAGGAAAGTACAAAG
ACATATATTGCTCCAGATGAATTTAACTTTACACCGTCAAGGTATTTTAAGTTTGGAAAGTTTATCGGAGCAGCAAGTCA
TTTTCAAATTCTTGCAAGTGAGCTTTCAGATCGTATGCTTGCCGAGTTTTTGGATATAGATGATAACATCAATATCTCTT
TTCATATCAAGGCAATTGAGCAGTCAGAAGCCATCAAGATGGTCAAAAGAAAAAATACCGATATTGACAAGATGAAGATT
GAGGAAAACAAAAAGGCTGTAAGGTCAGGGTATGACATGGACATTCTTCCAAGTGATTTAATCACCTATGGGGAAGATGT
AAAAAGCCTCTTAAAAGACTTACAGACAAGAGATGAGAGAATGTTTGTTGTAACCATCATTTTTATGAACTTTGCAAGGA
CAATTCAAAAGCTAGATAATACCATTTCTCAAATTAGCTCCATTGCCAATAAGCATAATTGCAAGTTAAAAAGGCTTGAC
CACTCACAGGAGCAGGGCTTAATCAGTGTACTTCCTCTTGGGGTAAATAAGATTGAAATTGATAGAGGGCTAACCTCATC
ATCTACGGCGGTCTTTATGCCGTTTACCACAGAGGAGCTTTTCATAAACTCGGCAAACAGTTTGTACTATGGACTAAATG
CCCTAAGTCATAACCTGATTATGGCAGATAGAAAGAAGTTAAAAAACCCGAACGGTCTAATCCTTGGAACTCCGGGAAGT
GGTAAATCCTTTAGTGCAAAAAGAGAAATGGCAAATGCCATTCTTACAACCGATGACGATGTGATTATCTGTGATCCGGA
AGGCGAATACGGAAACCTTGTAAGACAATTTAAGGGAGAAGTCATAAAGGTCAGCAGTAAGTCGAAGGACTATCTCAATC
CTTTAGATATAAATATGAACTATGGAGATGGTGACGCACCACTAAAGGACAAAGCAAACTTCATTATGTCTATGCTTGAA
CTTGTTGTAGGAGGTAGTGGTCTTACAGCAGAAGAAAAGTCGGTTATAGATAGATGTCTGCCTAAGATTTATGGAAAGTA
TTTTGAAAATCCAATTCTTGAGAATATGCCTATTCTTCAAGACCTGTATGATATGTTAAAAAATCAGGAAGAAAAAGTAG
GTAAAAAGTTGGCAACAGAAATGGAGATTTATGTAACAGGATCTCTTAATGTATTTAATAACAGGTCAAATGTGGACTTA
AATAAGCAGCTTCTTTGTTTTGATATTAAGGAGTTAGGCTCGCAGCTTAAAAAAATTGGAATGCTTGTTATTCAGGATCA
GGTGTGGAACAAGGTATCGCAAAACAGAGGAAATAAGGCTACAAGGTATTATATAGACGAGTTTCACCTATTGTTAAAAG
ACGAGCAGACAGCTTCCTATTCCGTAGAGATTTGGAAAAGATTTCGTAAGTGGGGTGGAATCCCGACAGGCATTACACAA
AATGTCAAAGACTTACTTATGAGTAATGAAATTGAAAATATCTTTGATAATACGGACTTTGTTTTAATGCTTAATCAGGC
TTCAGGCGATAGAGAAATTTTAGCAAGGAAACTTAAAATCTCTCAGCCACAGCTAAAATATGTAACTAATTCCAATGCAG
GAGAAGGACTTTTGTTCTTTGGAAACACCATTGTTCCTTTCCTTGATAAGTTCCCAAAAGACACAATACTTTATCAGAAG
ATGACAACCAAGCCTGAAGAAGTGAGGTAG

Protein sequence :
MNKKRKIQQLKLEQNKKKLRSQRQDLKQNKGKSKKDKGGLLDLIFRKEPKRYTVEDTIPYLRLLKSGICQIDENHFNKSI
AFEDINYQLALEEDRDLIFNQFANFLNSFDPSISIEFSYINQLGRNEEMKSAIQIPDKGDGFDDIRLEFREMLKSQIVKG
NNGLKKSKYVTFTVEADNLEQATSKLERMEIDILSSFKSMGVRAESLNGEERLKILHDVLNPNKTFEFSYKDLKKKESTK
TYIAPDEFNFTPSRYFKFGKFIGAASHFQILASELSDRMLAEFLDIDDNINISFHIKAIEQSEAIKMVKRKNTDIDKMKI
EENKKAVRSGYDMDILPSDLITYGEDVKSLLKDLQTRDERMFVVTIIFMNFARTIQKLDNTISQISSIANKHNCKLKRLD
HSQEQGLISVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSANSLYYGLNALSHNLIMADRKKLKNPNGLILGTPGS
GKSFSAKREMANAILTTDDDVIICDPEGEYGNLVRQFKGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLE
LVVGGSGLTAEEKSVIDRCLPKIYGKYFENPILENMPILQDLYDMLKNQEEKVGKKLATEMEIYVTGSLNVFNNRSNVDL
NKQLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATRYYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQ
NVKDLLMSNEIENIFDNTDFVLMLNQASGDREILARKLKISQPQLKYVTNSNAGEGLLFFGNTIVPFLDKFPKDTILYQK
MTTKPEEVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2320 NP_815976.1 traE protein Not tested Not named Protein 0.0 60
EFAU085_00716 YP_008394240.1 Type IV secretory pathway, VirB4 component Virulence Not named Protein 0.0 53