Gene Information

Name : thiC (CD630_17020)
Accession : YP_001088205.1
Strain : Clostridium difficile 630
Genome accession: NC_009089
Putative virulence/resistance : Unknown
Product : phosphomethylpyrimidine synthase ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : 4.-.-.-
Position : 1976366 - 1977667 bp
Length : 1302 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10382260, 9139923; Product type e : enzyme

DNA sequence :
ATGAACTATACAACACAAATGGATGCTGCTAGAAAAGGCATAATAACTAAAGAAATGGAAATCGTTTCTCAAAAAGAACA
GGTAGATGTAAATGAATTAAGAGAATTAATAGCAAATGGACAAGTTGTTATACCAGCTAATAAAAATCATAAATCTTTAA
GTGCAGAAGGTGTAGGTAAAAATTTAAGAACAAAAATAAATGTAAATCTAGGAATTTCAAGAGATTGTAAGGATATAGAA
AAAGAACTTGAAAAAGTTAGAGTAGCAATAGACATGAAAGCTGAAGCTATAATGGATTTAAGTAATTATGGCAAAACTAG
AGAATTTAGAGAAAAGGTTGTTGAAATGTCACCTGCAATGATAGGTTCAGTACCTATGTATGATGCAGTAGGATATTTGG
AAAAAGAATTAAAAGATATAACAGAAGAAGAGTTTTTAAATGTAATAAGACAACATGCTATTGATGGAGTAGACTTTATT
ACTATACATGCAGGTCTTACAAGAAGTGTTTGCCAAAAAATAAAAAATCATGAGAGATTGACTCATATAGTATCTCGTGG
AGGTTCTTTATTGTTTGCATGGATGGAATTAAATAATAAGGAAAATCCTATTTATACTAATTTTGATAAAATATTGGATA
TATGTGAAGAATATGATGTTACATTGAGTTTAGGAGATGCTTGTAGACCAGGTTGTATAAAAGATTCTACTGATGGTGTT
CAAATTCAAGAACTTGTAGTATTAGGTGAACTTACTAAAAGAGCATGGGAAAGAAATGTACAAGTAATGATAGAAGGTCC
TGGACACATGGCTATTGATGAAATAGAAGCAAATGTAGTATTAGAAAAGAGATTATGCCATGGAGCACCTTTTTATGTTC
TTGGACCATTGGTTACAGATATAGCACCAGGTTATGACCATATAACAAGTGCAATAGGAGGAGCTTTAGCATGTGCCAAA
GGAGTAGATTTTTTATGTTATGTAACTCCAGCAGAACATTTAAGATTGCCTAATTTAGATGATATGAAAGAGGGTATAAT
AGCTGCAAAGATAGCTGCTCATGCAGGAGATATAGCTAAAAATGTTAAAGGTGCTCGTGAATGGGATAATAAGATGAGTA
AAGCTAGAGCTGATTTAGACTGGTGTGAGATGTTTAGACTTGCAATAGACCCTGAAAAAGCTAAGAGATACAGAGATGAA
TCAACTCCTACTCATGAGGATAGTTGTACTATGTGTGGAAAAATGTGCTCAATGAGAACAGTTAAGAAAATATTAAACAA
TGAGGAACTTAATCTAATATAA

Protein sequence :
MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVIPANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIE
KELEKVRVAIDMKAEAIMDLSNYGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEYDVTLSLGDACRPGCIKDSTDGV
QIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIEANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAK
GVDFLCYVTPAEHLRLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPEKAKRYRDE
STPTHEDSCTMCGKMCSMRTVKKILNNEELNLI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 9e-70 46
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 9e-70 46