Gene Information

Name : serS1 (CD630_00140)
Accession : YP_001086477.1
Strain : Clostridium difficile 630
Genome accession: NC_009089
Putative virulence/resistance : Unknown
Product : seryl-tRNA ligase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 17952 - 19223 bp
Length : 1272 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9851985, 7540217; Product type e : enzyme

DNA sequence :
ATGTTAGATATTAAAAGAATAAGAGAAAATCTAGATGATATCAAAAAAGCTATGGAAAGAAGAGGTGAAAGAGAATTTGA
CCTTGATGCTGTAGTGGAATTAGATAATAAAAGAAGAGAAATACTTCAAGAAGTTGAAGTTATGAAAAATGAGTTAAATG
TAAATTCTAAAAAAATACCTCAATTAATAAAAGAAGGAAAAGATGTAACAGAAGAAAAGGCAAGATTGAAAGAGTTATCA
GATAAGATAAAAGGTATTGATGAGAAAGTAAAAGAAGTAGAAGCAAAAATGGAATATACATTAATGAGAATACCAAATGT
TCCTCATCCAGAGGTACCACAAGGTGAAACAGATGAAGACAATGTTCAAATAAGAACTTGGGGAGAACCTACTAAATTTG
ATTTTGAGCATAAAGCGCATTGGGATATAGGTACAGGTCTAGGTATTTTAGATTTTGAAAGAGCAGGGAAAATAACTGGG
TCAAGGTTTACTTTATATAGGGGATTAGGAGCTAGATTAGAAAGATCTTTAATGAATTTCTTTTTAAATACTCATACAGC
TAAGCATGGCTATACGGAAGTCTTACCTCCATTTATGGCCAATAGAAATAGTTTTATAGGGACTGGTCAACTTCCTAAAT
TTGAAGAAGATATGTTTAAAATAGAAGGATTAGAGTATTTCTTAATACCAACAGCTGAAGTTCCTGTTACTAATATACAT
GCTAATGAAATATTAGATGTTGCAGAGCTTCCAATTAAATACTGTGCATATACTCCTTGTTTTAGATCTGAAGCAGGTTC
AGCAGGAAGAGATACAAGAGGTTTAGTTAGACAACATCAATTTAATAAAGTTGAATTAGTTAAATTTGTTAAACCAGAAG
ATTCTTATAATGAATTAGAATCATTAACTCATGATGCTGAAACTATGTTACAAATGTTAGGTCTTCCATATAGAGTTGTA
AAAATATGTACAGGAGATTTGGGATTTACAGCTGCATTTAAATATGATTTAGAAGTTTGGATGCCAAGCTACAATAGATA
TGTAGAAATATCTTCTTGTTCAAATTTTGAAGATTTCCAAGCAAGAAGAGCAGGAATAAGATTTAAAAGGGATAAAAAAT
CAAAAGCAGAATATGTTCATACATTAAATGGTTCTGGATTAGCGATAGGAAGATGTTTGGCTGCTATATTAGAAAATTAT
CAGCAGGCAGATGGTTCTGTAGTAGTTCCAGAAGAATTAAGACCTTATATGGGTGTTGATGTTATAAAATAA

Protein sequence :
MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQEVEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELS
DKIKGIDEKVKEVEAKMEYTLMRIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDMFKIEGLEYFLIPTAEVPVTNIH
ANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLVRQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVV
KICTGDLGFTAAFKYDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRCLAAILENY
QQADGSVVVPEELRPYMGVDVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-115 57