Gene Information

Name : CD630_11100 (CD630_11100)
Accession : YP_001087599.1
Strain : Clostridium difficile 630
Genome accession: NC_009089
Putative virulence/resistance : Virulence
Product : hydrolase
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG3451
EC number : -
Position : 1306661 - 1309090 bp
Length : 2430 bp
Strand : -
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12568329, 12568327,17650959, 11157942,11073898, 8863741; Product type pe : putative enzyme

DNA sequence :
TTGTCAAAAGGACAAACAAAAAAGACGCGGGAAGCCGCAGGAAACAGGCGTAAGCTGACCCGCGCCGAAAAGAAACAGAT
TGCCGAAGCTATCCGAAAAGCAAAAGGCGACGGCAAAGCCCGCACCGCACAGCAGACCATTCCCTACCTTGCCATGTACC
CGGACGGTATCTGCAAGGTTACGGAAAAGAGATATTCAAAGTGCGTCATGTTCGAGGACATCAATTATCAGCTTGCACAG
GCTGACGATAAGACCGCCATTTTTGAAAACTGGTGCGATTTCCTCAATTACTTTGACGCGAGCGTGAGCGTGCAGCTTTC
TTTCATCAATCAAGGGACGCAGCGGGAACAGGCAGAAAAAGCTATCTCTATCCCGGCACAGGAGGACGCTTTCAACTCTA
TCCGCACCGAGTATTCCGATATGCTGAAAAATCAGCTTAGTAAAGGCAACAACGGGCTTGTGAAGCACAAATACATTACC
TTTACCGTTGAAGCTGATAACAAGGCGGCTGCAAAGTCAAGGCTTTCCCGTATCGAAACCGACGTACTTAACAATTTCAA
GGTGCTTGGCGTAACCGCCCGCCCCTTATCCGGCTATGAACACTTAAAGGTGCTGCATGGGGTATTCCACCCGGAGGGCG
AGCCGTTCTCCTTTTCCTTTGACTGGCTTACCCCGTCGGGGCTTACTACAAAGGACTTTATCGCCCCGTCCTCTTTCCAT
TTTGGCGAGGGCAGATATTTCCGCATGGGGAAGAAAATCGGCGCGGCGAGCTTCCTTGAAATCCTTGCGCCGGAACTCAA
CGACCGTATGCTTGCCGACATACTGGACTTGGAAACAGGCGTAATCGTCAACTTACATATCCGCAGTATCGACCAGTCGG
AAGCAATCAAGACCATTAAGCGCAAAATCACAGACCTTGACAAGATGAAGATTGAGGAACAGAAAAAAGCGGTTAGAAGC
GGCTATGACATGGATATAATCCCGTCCGACCTTGCCACCTTTGGCAGCGAAGCAAAGAACCTGTTGCAGGACTTACAGAG
CCGCAACGAGCGAATGTTTCTCCTTACGTTCCTTGTGGTAAACATGGCAGACACGAAGCGGAAACTGGAAAATGACATTT
TCGCGGCGGCGGGTATCGCACAGAAATACAACTGCCGCCTGACACGCCTTGACTATCAGCAGGAAGCGGGGCTTTTATCC
AGTGTGCCGATTGGGGAAAACCTTATCCCTATTCAGAGAGGTTTGACAACGAGCAGCACCGCTATTTTCATTCCCTTTAT
CACGCAGGAGCTTTTTCAGACGGGGCAAGCCCTTTACTATGGCTTGAACGCCCTTTCTAACAACATGATACTCTGCGACA
GAAAGCAGCTCAAAAACCCAAACGGGCTTATCTTGGGAACGCCGGGAAGCGGAAAATCCTTTGCGGCAAAAAGGGAAATG
ACAAACGCTTTTCTCATTACCGACGACGACATTATCATCTGCGACCCGGAAGCCGAGTATTTTTCCCTTGTGCAGCGTCT
TAATGGGCAAGTGATACGTCTTTCCCCTACGGGCAGGGGCATTGACGGCAAGCCCCAGTATGTGAACCCTATGGATATAA
ACCTTAATTACAGCGAGGACGACAACCCGTTAGCCTTAAAGTCCGATTTTATCCTTTCCCTCTGCGAGCTTGTTATTGGC
GGCAAGGAGGGCTTGCAGCCTGTCGATAAGACCGTCATTGACAGGGCTGTAAGAAATGTGTACCGCCCGTTCCTTGCAGA
CCCCGACCCGGCAAAAATGCCTATCTTGGGCGACCTTTACGACGAGCTGTTAAGGCAGCCGGAGCCGGAAGCTGCCCGTA
TCGCGGCGGCATTGGAGCTGTATGTTTCCGGCAGCCTTAACGTATTCAACCACAGAACCAACGTGGAACTGAATAACCGC
CTTGTCTGCTTTGATATAAAGCAGCTTGGGAAGCAGCTTAAAAAGTTAGGTATGCTCATTGTGCAAGACCAGACATGGAA
CAGGGTAACGATAAACCGGGCAGAAAAGAAATCCACCCGCTACTATATGGACGAGTTTCACTTGCTCTTAAAAGAGGAAC
AGACGGCAGCTTACAGCGTGGAGATTTGGAAGCGTTTCCGTAAATGGGGCGGCATACCCACAGCCATTACGCAGAACGTC
AAAGACCTTTTGGCAAGCCGCGAGGTGGAAAATATCTTTGAGAACAGCGATTTTGTCCTTATGCTCAATCAAGCGCAGGG
CGACCGTACTATCCTTGCAAAGCAGCTTAATATTTCCCCGCAGCAGATGAAGTATGTTATCCACACCGAAGCGGGCGAGG
GGCTTATCTTTTATGGAAATGTGGTGCTGCCTTTTGTAGACCGCTTCCCGAAAGATACCGAGCTTTACCGGGTAATGACG
ACGAAGCCGGAGGAAGTGAGCAGCCTATGA

Protein sequence :
MSKGQTKKTREAAGNRRKLTRAEKKQIAEAIRKAKGDGKARTAQQTIPYLAMYPDGICKVTEKRYSKCVMFEDINYQLAQ
ADDKTAIFENWCDFLNYFDASVSVQLSFINQGTQREQAEKAISIPAQEDAFNSIRTEYSDMLKNQLSKGNNGLVKHKYIT
FTVEADNKAAAKSRLSRIETDVLNNFKVLGVTARPLSGYEHLKVLHGVFHPEGEPFSFSFDWLTPSGLTTKDFIAPSSFH
FGEGRYFRMGKKIGAASFLEILAPELNDRMLADILDLETGVIVNLHIRSIDQSEAIKTIKRKITDLDKMKIEEQKKAVRS
GYDMDIIPSDLATFGSEAKNLLQDLQSRNERMFLLTFLVVNMADTKRKLENDIFAAAGIAQKYNCRLTRLDYQQEAGLLS
SVPIGENLIPIQRGLTTSSTAIFIPFITQELFQTGQALYYGLNALSNNMILCDRKQLKNPNGLILGTPGSGKSFAAKREM
TNAFLITDDDIIICDPEAEYFSLVQRLNGQVIRLSPTGRGIDGKPQYVNPMDINLNYSEDDNPLALKSDFILSLCELVIG
GKEGLQPVDKTVIDRAVRNVYRPFLADPDPAKMPILGDLYDELLRQPEPEAARIAAALELYVSGSLNVFNHRTNVELNNR
LVCFDIKQLGKQLKKLGMLIVQDQTWNRVTINRAEKKSTRYYMDEFHLLLKEEQTAAYSVEIWKRFRKWGGIPTAITQNV
KDLLASREVENIFENSDFVLMLNQAQGDRTILAKQLNISPQQMKYVIHTEAGEGLIFYGNVVLPFVDRFPKDTELYRVMT
TKPEEVSSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2320 NP_815976.1 traE protein Not tested Not named Protein 0.0 70
EFAU085_00716 YP_008394240.1 Type IV secretory pathway, VirB4 component Virulence Not named Protein 0.0 64