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Name : topB (CD630_11060) Accession : YP_001087593.1 Strain : Clostridium difficile 630 Genome accession: NC_009089 Putative virulence/resistance : Unknown Product : DNA topoisomerase III Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0550 EC number : 5.99.1.2 Position : 1300439 - 1302529 bp Length : 2091 bp Strand : - Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11395412, 12568329, 12568327, 17650959,11157942,11073898, 8863741; Product type e : enzyme DNA sequence : TTGATTTTAGTTATCGCAGAAAAACCCAGTGTGGCGCAGACAATCGCCGCCGTACTTGGGGTAAAGGAAAAGAAAGACGG ATTTCTCACAGGAAGCGGCTATATCGTTTCTTGGTGCGTGGGACATTTGGTAGGGCTTGCGGAAGCTGCCGCCTACGGGG AACAGTATAAAAAGTGGAACTATGACAGCTTACCGATTTTGCCGCAGGAATGGAAATACACCGTTGCTGCCGACAAGGAA AAGCAATTTAAAACCCTAAAAGAGCTTATGCACCGGGCAGATGTTTCCGAAGTCGTCAATGCCTGCGACGCAGGGCGCGA GGGAGAACTCATTTTCCGCTTTGTCTATGAAATGGCGGGCTGCAAGAAACCTATGCGCCGCCTTTGGATTTCTTCTATGG AGGACAGCGCAATCAAAGAGGGCTTTTCCCGTCTGAAGAACGGCAAGGAATACGACGCGCTCTTTGCTTCCGCACTATGC AGGGCAAAGGCTGACTGGCTAATCGGTATCAATGCCACCCGCCTTTTCTCTGTCCTTTACAATCATACCTTGAACGTGGG GCGTGTACAGACCCCGACCTTAAAAATGCTTGTTGACCGGGACGCAGCGATTACCACTTTCAAGAAAGAAAAATACTACC ATGTGCGCCTTGCCTTATCCGGCGCGGAAGCTGCAAGTGAAAGAATTTCAAATAAGGCAGAAGCCGACACATTAAAAACG ACTTGCGAAGCGTCAAAAGCAGTCTGTACTTCCCTTTTGAAAGAGAAAAAGACCGCAGCCCCGCCGAAGCTCTTTGACCT TACTTCTTTACAGAGGGAAGCAAACTGCCTGTTCGGATATACGGCAAAGCAGACCCTTGACCTTGCACAAGCCCTGTATG AAAAAAGACTTCTTACTTATCCGAGAACAGACAGCAGCTATCTGACTGACGACATGGGCGACACAGCAGCGGGCATTATC AAGCTGCTTTGCGGGAAATTTCCTTTTATGGCGGGAAAAGACTTCACGCCGGAGCTTGCAAAGGTGCTGAACAGTAAAAA GGTATCAGACCACCATGCCATTATCCCGACTATGGAGCTTGCAAAGACCGACCTTGCCGCGCTGCCGGAAAGCGAAAGGA ATATCCTTACCATTGCCGGGGCGCGTCTGATTATGGCGACTGCCGCACCGCATACCTTTGAAGCGGTTACGGCAGTTTTT GAGTGTGCCGGACAGTCCTTTACCGCAAGGGGAAAAACGGTACTGTCCGACGGGTGGAAAGAGATTGACCGAAAATACAG GGCAATCTTAAAGAGTAAGCCTGAAACGGACGACGCAGACAGCGACACAGAAAAGACCCTGCCGCCGTTTACCGAGGGAC AGAACTTTGACAATCCAGCGGCAAAGGTAACGGAGCATGACACAACACCGCCAAAGCCCCACAATGAAGCGTCGCTCCTT TCCGCTATGGAGCGCGCCGGAAGCGAGGACACCGACCCGGACGCAGAACGCAAAGGGCTTGGAACTCCCGCCACCCGCGC CGCCGTCATTGAAAAACTGGTAAAGGGCGGCTTTGTGGAGCGAAAAGGCAAGCAGCTACTTCCCACAAAAGACGGTATCA ACCTTGTGTGCGTCCTGCCGGACACCTTGACAAGCCCGCAGCTTACCGCAGAATGGGAAAACAATCTGACGCAGATTGCC AAAGGCAAGGCAGACCCCGCCGCATTTATGAAGGGTATCGAGGATATGGCGCGAGAACTGGTAAAGACCTATCCGTTTCT TTCCGAAGCTGACAAGGGGCGTTTCAAAGAGGAAAAGCCGGAGCTTGGGAAATGTCCCCGCTGTGGTTCTCCTGTCTATG AGGGAAAGAAAAACTACTATTGCAGCAACAAAGAATGTAGCTTTACCATGTGGAAAAATGACCGTTTCTTTGAAGAACGA AAAGTAACCTTTACCCCGAAGATTGCCGCTGCACTCTTAAAATCCGGCAAGGTAAATGTGAAGAAGCTCTATTCCCCAAA GACAGGCAAAACTTACGACGGAACTATCGCATTGGCTGATACAGGCGAGAAATATGTCAACTACCGCATTGAACTGTCGA AGAAGAAATAA Protein sequence : MILVIAEKPSVAQTIAAVLGVKEKKDGFLTGSGYIVSWCVGHLVGLAEAAAYGEQYKKWNYDSLPILPQEWKYTVAADKE KQFKTLKELMHRADVSEVVNACDAGREGELIFRFVYEMAGCKKPMRRLWISSMEDSAIKEGFSRLKNGKEYDALFASALC RAKADWLIGINATRLFSVLYNHTLNVGRVQTPTLKMLVDRDAAITTFKKEKYYHVRLALSGAEAASERISNKAEADTLKT TCEASKAVCTSLLKEKKTAAPPKLFDLTSLQREANCLFGYTAKQTLDLAQALYEKRLLTYPRTDSSYLTDDMGDTAAGII KLLCGKFPFMAGKDFTPELAKVLNSKKVSDHHAIIPTMELAKTDLAALPESERNILTIAGARLIMATAAPHTFEAVTAVF ECAGQSFTARGKTVLSDGWKEIDRKYRAILKSKPETDDADSDTEKTLPPFTEGQNFDNPAAKVTEHDTTPPKPHNEASLL SAMERAGSEDTDPDAERKGLGTPATRAAVIEKLVKGGFVERKGKQLLPTKDGINLVCVLPDTLTSPQLTAEWENNLTQIA KGKADPAAFMKGIEDMARELVKTYPFLSEADKGRFKEEKPELGKCPRCGSPVYEGKKNYYCSNKECSFTMWKNDRFFEER KVTFTPKIAAALLKSGKVNVKKLYSPKTGKTYDGTIALADTGEKYVNYRIELSKKK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| EFAU085_00720 | YP_008394244.1 | DNA topoisomerase III | Not tested | Not named | Protein | 0.0 | 67 |
| topB-2 | NP_815968.1 | DNA topoisomerase III | Not tested | Not named | Protein | 0.0 | 52 |
