Gene Information

Name : lysS (A1S_0998)
Accession : YP_001084032.1
Strain : Acinetobacter baumannii ATCC 17978
Genome accession: NC_009085
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1155657 - 1156943 bp
Length : 1287 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTTAAACCGTGGTTCTTTCATGGTGATTCAAGACATGACTGGTCGTATCCAATTATATGTTGACCGTAAAGGTTTACC
AAAAGATACGCTTGAAACTATTAAAGGTTTAGACCTTGGCGATATTATTGCTGCTGAAGGTTATATCGGTCGTTCTGGCA
AAGGTGACTTATATGTACACCTTGAAGGTTTTGAACTTCTTACAAAATCGCTTCGTCCATTGCCGGATAAATTTCATGGT
TTGAACGACACAGAAGTTAAATATCGTAAGCGTTATCTTGACTTAATTGTGAATGAAGAAACGCGTAAGACTTTTGAAAT
TCGTGCCAAAGTCGTTGCAGGTATTCGCGCATTTTTAACCAATGAACGTTTCATGGAAGTTGAAACGCCAATGATGCATG
TGATTCCGGGTGGTGCGTCTGCACGTCCGTTTGAGACGCATCATAATGCTTTAGATATGCCATTATTCTTACGTATCGCA
CCAGAGCTTTATTTAAAACGTTTAGTTGTTGGTGGTTTTGAGCGTGTGTTTGAAATTAACCGTAACTTCCGTAATGAAGG
GGTATCAACACGTCATAACCCTGAATTTACCATGATCGAGTTTTATCAGGCATATGCTGATTATAAAGACTTGATGGCTT
TGACTGAAAACATGCTTGAAAAGCTAGCAATTGATATTTTAGGTACGACTGATGTGCCTTACCAAGGCGAAGTGTTTAGC
TTTAAAGGGCCATTCAAGAAAATCTCTATGTTTGATGCGATTTTGGAGAATAATCCGCAGTTCACGCCTGAAAATGTAGG
CGATCGTGAATTCCTTGCAAAATTTGTTCGTGAGGAATTAAAAGAAGAAGTTAAACCTGGTTTTGGTTTAGGTAAGCTTC
AAACAATCGTATTTGAAGAAACGGTTGAGACTAAACTTCGTCAGCCTACTTTTATTACTGAGTACCCAGCAGAGACTTCT
CCACTTGCTCGCCGTAATGATGATAATCCGCACATTACTGATCGTTTTGAGTTCTTTATTGGTGGCCGTGAATTGGCAAA
CGGCTTTAGTGAGTTAAATGATCCGATTGATCAGGCTGAACGTTTCCAAGCGCAAGTTGCTGAAAAAGATGCTGGTGATG
ATGAAGCAATGCATTACGATGCAGAGTTTGTTGAAGCACTTGAATATGGTTTACCTCCAACAGCGGGTGAAGGTATTGGT
ATTGACCGTTTGGTTATGCTTTTTGCAGATGCACCAAGTATTCGTGATGTGATTTTGTTCCCGCATATGCGTCGTAAAGA
AGGTTAA

Protein sequence :
MLNRGSFMVIQDMTGRIQLYVDRKGLPKDTLETIKGLDLGDIIAAEGYIGRSGKGDLYVHLEGFELLTKSLRPLPDKFHG
LNDTEVKYRKRYLDLIVNEETRKTFEIRAKVVAGIRAFLTNERFMEVETPMMHVIPGGASARPFETHHNALDMPLFLRIA
PELYLKRLVVGGFERVFEINRNFRNEGVSTRHNPEFTMIEFYQAYADYKDLMALTENMLEKLAIDILGTTDVPYQGEVFS
FKGPFKKISMFDAILENNPQFTPENVGDREFLAKFVREELKEEVKPGFGLGKLQTIVFEETVETKLRQPTFITEYPAETS
PLARRNDDNPHITDRFEFFIGGRELANGFSELNDPIDQAERFQAQVAEKDAGDDEAMHYDAEFVEALEYGLPPTAGEGIG
IDRLVMLFADAPSIRDVILFPHMRRKEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 6e-122 60
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 4e-81 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001084032.1 lysyl-tRNA synthetase VFG1668 Protein 4e-122 60