Gene Information

Name : thyA (A1S_0458)
Accession : YP_001083515.1
Strain : Acinetobacter baumannii ATCC 17978
Genome accession: NC_009085
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 495155 - 495898 bp
Length : 744 bp
Strand : -
Note : TS; TSase; ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGCGTTTTGATCTCTCTAAGGGTTTTCCTTTACTCACCACAAAAAAAGTTCACTTTCGTTCTATCGTGATTGAGTTACT
TTGGTTCTTAAAAGGCGATACTAACGTTAAGTACTTACAAGACAATAAAGTCACCATTTGGGATGAATGGGCAACAGCAG
AACAAACTGCCCGTTTCGGCCGCCCAGAACATGAGCTTGGCCCAGTTTATGGCCATCAATGGCGTAATTTCGGCGCAACT
AAAAATGCCGATGGTACTTATAACCAAGATGGTTTTGACCAAATTAAATGGTTAATTAATGAAATTAAAACCAACCCAAA
TTCACGCCGTTTAATTGTCTCTGGCTGGAACCCAAATGAGGCTGGACAAGTTGCTTTACCGCCTTGCCATACGCTCTTCC
AATTCTTTGTACAAGACAACAAGTTGTCATGCCAGCTTTATCAACGTAGTGCTGACGTATTCTTAGGCGTGCCATTTAAT
ATTGCCAGTTATGCCTTACTCACTCATATGATTGCTCAAGTGTGTGGCTTAGATGTTGGTGATTTTGTTTGGACAGGTGG
CGATACGCATCTTTATGCCAACCATTTTGAGCAGGCAAAACTACAATTGACGCGTGAGCCATTACCACTTTGCCAATTAA
AACTTAATCCGGATGTTAAAGATATTTTCGACTTCAAATTTGAAGACATCGAGATTGTAGGTTACGAGTCACATCCGGCA
ATTAAAGCACCAGTTGCAGTATAA

Protein sequence :
MRFDLSKGFPLLTTKKVHFRSIVIELLWFLKGDTNVKYLQDNKVTIWDEWATAEQTARFGRPEHELGPVYGHQWRNFGAT
KNADGTYNQDGFDQIKWLINEIKTNPNSRRLIVSGWNPNEAGQVALPPCHTLFQFFVQDNKLSCQLYQRSADVFLGVPFN
IASYALLTHMIAQVCGLDVGDFVWTGGDTHLYANHFEQAKLQLTREPLPLCQLKLNPDVKDIFDFKFEDIEIVGYESHPA
IKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 1e-63 57
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 3e-63 50