Gene Information

Name : Mjls_0703 (Mjls_0703)
Accession : YP_001069005.1
Strain : Mycobacterium sp. JLS
Genome accession: NC_009077
Putative virulence/resistance : Virulence
Product : two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 747777 - 748490 bp
Length : 714 bp
Strand : -
Note : PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mmc:Mmcs_0709 two component transcriptional regulator, winged helix family

DNA sequence : 
GTGACACGCGTCCTGATCGCCGACGACGACTCCGTCGTGCGGGATGTCGTGCGCCGATACCTCGAACGCGACGGCCTCGA
AGTGGCCATCGCCCGCGACGGCACCGAGGCGCTGCGACTGCTCGGCACCGAGCGGATCGACGTCGCCGTACTCGACGTGA
TGATGCCCGGACCCGACGGGATGACGCTGTGCCGCACCCTGCGCCAGCGCGGCGAGCACACCGTCCCGGTCATCCTGTTG
ACCGCCCTCGGCGAGGAGGACGACCGCATCGCCGGACTGGAAGCCGGCGCGGACGACTACCTGACCAAACCGTTCAGCCC
GCGGGAACTGGCCCTGCGGGTGCGTTCGGTGCTGCGCCGTTCACCGACACCGGTCGGGGTGACCCCGGTCGACCTGACGG
TCGGCGCCCTCACGATCTCTGCAGCCGCCCGCTCGGTCACCGTCGACGGCCGGCCGGTCAGCCTCACCAACCGCGAATTC
GACCTGCTGCTGTTCTTCATCACCCACGCCGACACCGTGTTCACCCGCGAAGAGCTGCTCAAGCAGGTGTGGCGGTGGGA
TTTCGGCGATCTGTCCACGGTGACCGTGCACGTCAAACGGTTGCGTTCCAAGCTCGGCGACCAGCACCGGGTGCAGACGG
TGTGGGGCCGCGGCTACATGTGGAGCGACACCGCAGGCGCCCGTGAAGGCCTGGCCAGCGGTGCCGTCAACTGA

Protein sequence : 
MTRVLIADDDSVVRDVVRRYLERDGLEVAIARDGTEALRLLGTERIDVAVLDVMMPGPDGMTLCRTLRQRGEHTVPVILL
TALGEEDDRIAGLEAGADDYLTKPFSPRELALRVRSVLRRSPTPVGVTPVDLTVGALTISAAARSVTVDGRPVSLTNREF
DLLLFFITHADTVFTREELLKQVWRWDFGDLSTVTVHVKRLRSKLGDQHRVQTVWGRGYMWSDTAGAREGLASGAVN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mprA YP_005684640.1 response regulator mprA Not tested PiCp 3 Protein 2e-26 41
mprA YP_005680459.1 response regulator mprA Not tested PiCp 3 Protein 2e-26 41
mprA YP_005682550.1 response regulator mprA Not tested PiCp 3 Protein 2e-26 41
tcsR1 YP_003782583.1 two-component system transcriptional regulatory protein Not tested PiCp 3 Protein 2e-26 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mjls_0703 YP_001069005.1 two component transcriptional regulator NC_002952.2859905.p0 Protein 1e-31 44
Mjls_0703 YP_001069005.1 two component transcriptional regulator NC_003923.1003749.p0 Protein 1e-31 44
Mjls_0703 YP_001069005.1 two component transcriptional regulator NC_002758.1121668.p0 Protein 1e-31 44
Mjls_0703 YP_001069005.1 two component transcriptional regulator NC_009641.5332272.p0 Protein 1e-31 44
Mjls_0703 YP_001069005.1 two component transcriptional regulator NC_013450.8614421.p0 Protein 1e-31 44
Mjls_0703 YP_001069005.1 two component transcriptional regulator NC_007793.3914279.p0 Protein 1e-31 44
Mjls_0703 YP_001069005.1 two component transcriptional regulator NC_002745.1124361.p0 Protein 1e-31 44
Mjls_0703 YP_001069005.1 two component transcriptional regulator NC_009782.5559369.p0 Protein 1e-31 44
Mjls_0703 YP_001069005.1 two component transcriptional regulator NC_002951.3237708.p0 Protein 1e-31 44
Mjls_0703 YP_001069005.1 two component transcriptional regulator NC_007622.3794472.p0 Protein 1e-31 44
Mjls_0703 YP_001069005.1 two component transcriptional regulator AE000516.2.gene3505. Protein 5e-26 42
Mjls_0703 YP_001069005.1 two component transcriptional regulator BAC0347 Protein 2e-24 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mjls_0703 YP_001069005.1 two component transcriptional regulator VFG1389 Protein 2e-27 44