Gene Information

Name : Mjls_5142 (Mjls_5142)
Accession : YP_001073397.1
Strain : Mycobacterium sp. JLS
Genome accession: NC_009077
Putative virulence/resistance : Virulence
Product : ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 5383840 - 5386383 bp
Length : 2544 bp
Strand : -
Note : PFAM: UvrB/UvrC protein; AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: mmc:Mmcs_4756 ATPase AAA-2

DNA sequence :
ATGTTCGAACGTTTTACCGACCGTGCCCGCAGGGTCGTCGTCCTGGCTCAAGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTGCTGGGACTCATTCACGAGGGTGAGGGCGTAGCGGCCAAGTCTCTCGAGTCGCTGGGCA
TCTCGCTGGAAGGCGTGCGCAGCCAGGTCGAGGAGATCATCGGCCAGGGCCAGCAGGCGCCGTCCGGTCACATCCCCTTC
ACCCCGCGCGCCAAGAAGGTGCTCGAGCTGTCCCTGCGCGAGGCGCTGCAGCTCGGCCACAACTACATCGGCACCGAGCA
CATCCTGCTCGGGTTGATCCGTGAGGGCGAAGGCGTCGCCGCTCAGGTTCTCGTGAAGCTCGGCGCCGAACTGACGCGCG
TGCGCCAGCAGGTCATCCAGCTGCTGTCCGGCTACCAGGGCAAGGAGTCCGCGGAGGCCGGCACCGGCGGCCGCGGCGGC
GAATCCGGCAACCCCTCGACCTCGTTGGTGCTCGACCAGTTCGGCCGCAACCTGACCGCCGCCGCGATGGAGGGCAAGCT
CGACCCCGTCATCGGCCGCGAGAAGGAAATCGAGCGGGTCATGCAGGTGCTGAGCCGCCGCACCAAGAACAACCCCGTGC
TGATCGGCGAGCCCGGCGTCGGCAAGACCGCCGTCGTCGAGGGCCTCGCGCAGGCGATCGTCCACGGCGAGGTGCCCGAG
ACGCTGAAGGACAAGCAGCTCTACACCCTCGACCTGGGCTCACTGGTCGCCGGCAGCCGCTACCGCGGTGACTTCGAGGA
GCGCCTGAAGAAGGTGCTCAAGGAGATCAACACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACGCTCGTCG
GCGCGGGTGCCGCCGAGGGCGCGATCGACGCCGCCAGCATCCTCAAGCCGAAGCTGGCCCGCGGTGAGCTGCAGACCATC
GGCGCCACCACCCTCGACGAGTACCGCAAGTACATCGAGAAGGACGCCGCCCTGGAACGCCGCTTCCAGCCGGTGCAGGT
GGGTGAGCCGACCGTCGAGCACACCATCGAGATCCTCAAGGGTCTGCGCGACCGGTACGAGGCGCACCACCGCGTCTCGA
TCACCGACAGCGCGATGGTGGCCGCCGCGACGCTGGCCGACCGCTACATCAACGACCGGTTCCTGCCGGACAAGGCGATC
GACCTGATCGACGAGGCCGGCGCCCGGATGCGGATCCGCCGGATGACCGCTCCGCCGGACCTGCGCGAGTTCGACGAGAA
GATCGCCGACGCCCGCCGGGAGAAGGAGTCCGCGATCGACGCGCAGGACTTCGAGAAGGCCGCGAGCCTGCGCGACAAGG
AGAAGCAACTCGTCGCCCAGCGTGCCGAGCGGGAGAAGCAGTGGCGCTCGGGTGATCTGGACGTCGTGGCCGAGGTCGAC
GACGAGCAGATCGCCGAGGTGCTCGGCAACTGGACCGGCATCCCCGTGTTCAAGCTGACCGAGGAGGAGACGACTCGGCT
GCTGCGCATGGAGGATGAGCTGCACAAGCGGATCATCGGCCAGGAGGACGCCGTCAAGGCGGTCTCGAAGGCGATCCGCC
GCACCCGCGCCGGGCTGAAGGACCCCAAGCGGCCGTCGGGTTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACC
GAGCTCTCGAAGGCGCTGGCGAACTTCCTGTTCGGCGACGACGATGCGCTCATCCAGATCGACATGGGCGAGTTCCACGA
CCGCTTCACCGCGTCGCGGCTGTTCGGTGCCCCTCCGGGCTACGTCGGTTACGAAGAGGGCGGCCAGCTCACCGAGAAGG
TGCGGCGCAAGCCGTTCTCGGTCGTGCTGTTCGACGAGATCGAGAAGGCCCACCAGGAGATCTACAACAGCCTCCTGCAG
GTCCTCGAGGACGGCCGTCTCACCGACGGTCAGGGCCGCACGGTCGACTTCAAGAACACCGTGCTGATCTTCACCTCGAA
CCTCGGTACCTCCGACATCAGCAAGGCGGTCGGGCTGGGCTTCACCCAGGGCGGCGGCGAGAACAACTACGAGCGGATGA
AGCAGAAGGTCAACGACGAGCTGAAGAAGCACTTCCGCCCGGAGTTCCTCAACCGCATCGACGACATCATCGTGTTCCAC
CAGCTGACGCAGGACGAGATCATCAAGATGGTCGACCTGATGATCGGCCGGGTCGGCAATCAGCTGCGGGCCAAGGACAT
GACGATGGAGCTCACCGACCGGGCCAAGTCACTGCTGGCCAAGCGCGGGTTCGACCCCGTGCTCGGTGCGCGGCCGCTGC
GTCGCACGATCCAGCGCGAGATCGAGGACCAGCTGTCGGAGAAGATCCTGTTCGAGGAGATCGGACCCGGTCAGCTGATC
ACCGTGGACGTCGAGAACTGGGACGGCCAGGGAGCGGGCGAGGACGCGAAGTTCACCTTCAGCGGTGGTCCGAAGCGGTC
CGAGCCGGTCGAGCCGGATCTGGCGCAGGCCGGCGCCGCCGGTGCGCCGAGCGCAGCCGAGTAA

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKESAEAGTGGRGG
ESGNPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPE
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRFLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIADARREKESAIDAQDFEKAASLRDKEKQLVAQRAEREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEEETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQ
VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKAVGLGFTQGGGENNYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
QLTQDEIIKMVDLMIGRVGNQLRAKDMTMELTDRAKSLLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEIGPGQLI
TVDVENWDGQGAGEDAKFTFSGGPKRSEPVEPDLAQAGAAGAPSAAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 82

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mjls_5142 YP_001073397.1 ATPase VFG0079 Protein 0.0 60
Mjls_5142 YP_001073397.1 ATPase VFG0080 Protein 1e-145 50