Gene Information

Name : Mjls_4547 (Mjls_4547)
Accession : YP_001072805.1
Strain : Mycobacterium sp. JLS
Genome accession: NC_009077
Putative virulence/resistance : Resistance
Product : copper-translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 4771606 - 4773738 bp
Length : 2133 bp
Strand : -
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: mmc:Mmc

DNA sequence :
ATGACAAACCGCGATGACCACGGCGTAGCAACATCCCACCCTGGCGGGCACGCCCACCACCAATTCCCCAGCGCACACCC
TGACACCCACCCACACGGCGAACACCACGGCCATGACAATCACACCGGCCACACGGGCCATAGCGGCCACGGCGGTGACC
ACGTGGCCCAATTCCGCAAGCTCTTCTGGATCAACCTGATCATCGCCATACCGGTCGTCGCGTTCTCGACCATGTTCGCG
ATGCTGCTCGGTTACGACGTCCCCGACTTCCCCGGCGCACGCTGGATCGCGCCCCTGCTCGGGACAGTGATGTACGTCGT
CGGTGGCCGCCCCTTCCTCACCGGTGCGCTGAACGAGATCCGTTCCCGCAAACCAGGAATGATGCTCCTGATCGGACTGG
CGATCACCGTCGCCTTTTTCGCGTCCTGGGGCGCGAGCTTGGGCCTGCTCCACCACGAGCTGGAATTCTGGTGGGAACTC
GCCCTTCTCATCGTCATCATGCTGCTCGGCCACTGGGTAGAAATGCGCTCGCTGGCCCAGACCACCTCAGCGCTGGACTC
ACTGGCCGCACTACTTCCCGACGAAGCCGAGAAGATCGACGGCGACCGCACCGTCACCGTCTCGCCGACCGACCTGCACG
TCGGCGATGTCGTTGTAGTCCGACCGGGCGGCAGCATCCCTGCCGACGGCAAGATCGTCGACGGACGCGCCGACATGGAC
GAGTCCATGGTGACCGGCGAATCCCGGCCCGTTACCCGCGGCGTCGGGGATCCCGTCACAGCCGGCACCGTCGCCACCGA
TTCCGGGCTTCGGGTCGAGATCACCGCCACCGGCGACGACACCGCCCTAGCAGGCATCCAACGCCTAGTCACCGAAGCCC
AGAATTCGTCCTCGCGTGCCCAGCGCCTTGCTGACAAGGCCGCCGGCTGGCTGTTCTGGTTCGCCCTGATCACCGCCGCG
ATCACCGCGGCGGCATGGACAATCGTCGGCAATCCCGATGCCTCGGTGGTACGAGCGATCACCGTGCTGGTCATCGCCTG
CCCTCATGCGCTGGGCCTGGCGATACCACTGGTCGTGTCCATCGCCACCGAACGCGCCGCCAGAGGCGGCGTCTTGATCA
AAGATCGGCTGGCCCTGGAAGGTATGCGCACTGTCGACGCCGTGCTGTTCGACAAGACCGGCACCCTGACGAAAGGCGAA
CCCACCGTCACCGCCGTCGAGGCGACCGGAGACGACGACGGCGACACCGTGCTCGCGCTCGCCGCCGCCGCCGAGACCGA
CAGTGAACACCCCCTGGCGCGGGCCATCGTGAAAGCCGCCGAGGATAGGGGATTAACGGTGCCGCGCGCCAGCGGCTTCT
CGTCCTCTCCTGCCGTCGGTGTGACTGCGACGGTCGACGGGCACGAAATCCGAGTGGGCGGCCCCCGACTTCTCGAAGAA
GTCGGCGCCCAGGAGGTCCCCGCGGCCACCGCGTGGCGCGGCGAAGGCGCCATCATTCTGCACGTCATCCGCGACGGAGA
GGTGCTCGGCGGCCTGCGCTTGGCCGACGAGATCCGCCCCGAATCCCGCGAAGCCGTCGATGCGCTTCACAAGCTTGGCG
TGCAAGTCGTCATGATCACCGGCGACGCCGAAGCCGTCGCCAATAGTGTCGGCCACCAGCTGGGCATCGACCGGGTGTTC
GCGGGGGTGCGCCCCGAAGACAAGGTGTCGAAAGTTGCTGCCCTGCAAGACGAGGGCAAGAAGGTTGCCATGGTCGGCGA
TGGAGTCAACGATGCCCCCGCCTTGGCGCAGGCCGATGTCGGCATCGCCATCGGTGCCGGCACTGACGTCGCCATCGCTT
CCGCCGGTGTCATCCTGGCCAGTTCCGACCCCCGCTCGGTGCTGTCGGTCATCGAGCTGTCTCGCGCCAGCTACCGCAAG
ATGAAACAGAATCTCTGGTGGGGCGCCGGGTACAACCTCATCTCTGTGCCCCTGGCTGCTGGTGTGCTGGCGCCCATCGG
CATCGTGCTGCCCATGTCGGTCGGCGCCCTCCTCATGTCACTGTCAACGATCGTCGTCGCGCTCAACGCGCAACTTCTGC
GCCGCCTCGATTTGACGCCCGAGGCGAGCACCCGCGCCGTTCTCAACCGTTAG

Protein sequence :
MTNRDDHGVATSHPGGHAHHQFPSAHPDTHPHGEHHGHDNHTGHTGHSGHGGDHVAQFRKLFWINLIIAIPVVAFSTMFA
MLLGYDVPDFPGARWIAPLLGTVMYVVGGRPFLTGALNEIRSRKPGMMLLIGLAITVAFFASWGASLGLLHHELEFWWEL
ALLIVIMLLGHWVEMRSLAQTTSALDSLAALLPDEAEKIDGDRTVTVSPTDLHVGDVVVVRPGGSIPADGKIVDGRADMD
ESMVTGESRPVTRGVGDPVTAGTVATDSGLRVEITATGDDTALAGIQRLVTEAQNSSSRAQRLADKAAGWLFWFALITAA
ITAAAWTIVGNPDASVVRAITVLVIACPHALGLAIPLVVSIATERAARGGVLIKDRLALEGMRTVDAVLFDKTGTLTKGE
PTVTAVEATGDDDGDTVLALAAAAETDSEHPLARAIVKAAEDRGLTVPRASGFSSSPAVGVTATVDGHEIRVGGPRLLEE
VGAQEVPAATAWRGEGAIILHVIRDGEVLGGLRLADEIRPESREAVDALHKLGVQVVMITGDAEAVANSVGHQLGIDRVF
AGVRPEDKVSKVAALQDEGKKVAMVGDGVNDAPALAQADVGIAIGAGTDVAIASAGVILASSDPRSVLSVIELSRASYRK
MKQNLWWGAGYNLISVPLAAGVLAPIGIVLPMSVGALLMSLSTIVVALNAQLLRRLDLTPEASTRAVLNR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SH0105 YP_252020.1 hypothetical protein Not tested SCCmec Protein 2e-87 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mjls_4547 YP_001072805.1 copper-translocating P-type ATPase BAC0629 Protein 8e-116 46
Mjls_4547 YP_001072805.1 copper-translocating P-type ATPase BAC0383 Protein 1e-104 43
Mjls_4547 YP_001072805.1 copper-translocating P-type ATPase BAC0101 Protein 5e-80 43
Mjls_4547 YP_001072805.1 copper-translocating P-type ATPase BAC0079 Protein 9e-114 42