Gene Information

Name : Mjls_3482 (Mjls_3482)
Accession : YP_001071751.1
Strain : Mycobacterium sp. JLS
Genome accession: NC_009077
Putative virulence/resistance : Virulence
Product : AMP-dependent synthetase and ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 3666815 - 3668464 bp
Length : 1650 bp
Strand : +
Note : PFAM: AMP-dependent synthetase and ligase; KEGG: mmc:Mmcs_3471 AMP-dependent synthetase and ligase

DNA sequence : 
ATGAGCACCGGATTCCAGCATGTGCACAGCGACCTGACCGATGGCTTCGTCCCATTCCCCGAAGACCGCGCCGAGCAGTA
CCGGCGGGCCGGGTACTGGACCGGGCGGCCCCTCGAGTCCCTTCTCCTCGACGCGGCACACCGACGGCCCGATCACCCGG
CCGTCGTCGACGTCGACGGATCCCTCACGTTCGCGGAGCTGACCGCGCGCGCCGACACCGTCGCCGCGGCGCTGGCCGGA
CTCGGGATCCGTCCTGGTGACCGGGTGCTGCTGCAACTACCCAACTCCGTGCGTTTCGCCGTCGCGTTCTTCGGTCTGCT
GCGGGCGGGCGCGGTGCCGGTGATGTGCCTGCCCGGCCACCGCACCGCCGAGCTGGGACACTTCGCCGACGTCAGCGGCG
CGGTGGCGCTGATCGTGCCCGACGAGGTCGGCGGCTTCGACTACCGCGAGATGGCCGCCCAGTTGGTGGCGGACCGGCCC
ACGCTGCGGCACGTGCTCGTCGACGGTGACCCGGGACCGTTCCTATCGTGGGCGGCACTGATCGACAGCGGCGGCGTGGC
ACCGGAGATCGGACCCGTCGACACCTCGCTGCCTGCCCTGCTGCTGGTCTCCGGCGGAACGACCGGACTGCCCAAGCTGA
TCCCCCGCACCCACGACGACTACGTCTACACCGCGGTGTCGAGCGCGCAGGCGTGCCACTTCACCCCCGACGACGTCTAC
CTGGTGGCGTTGCCGGCCGGCCACAACTTCCCGTTGGCGTGCCCCGGCATGCTGGGGGCAATGACCGTGGGGGCGACGAC
GGTGTTCACCGCCGATCCCAGCCCGGAGGAGGCGTTCGCGCTCATCGACAAACACCAGGTGACCGTCACCGGGCTGGTCA
ACGCGCTGGGCAAGCTGTGGGCGCAGGCGTGCGACTGGGAACCGGTGCTGCCGACGTCGCTGCGCCTGGTGCAGGTGGGC
GGTTCGCGGATGAGCCCGGAGGAGGCGCGGTTCATCCTCGATCTCCTGACCCCCGGGCTGTCCCAGATCTTCGGAATGGC
CGAGGGCATGCTGAATTTCACGCGGCCGGGAGATCCGCTCGACGTCGTGGTGCACACCCAGGGCAGGCCGGTCTCCCCGC
ACGACGAGATGCGGGTGGTCGACGAGTCCGGTGTCGAGGTCGCACCGGGCGAAGAGGGCGAACTGCTGGTGCGCGGTCCC
AACACACTCAACGGGTACTACCGGGCCGACGAGGCCAACGCCCGGTGCTTCAGCCCGGACGGCTTCTACCGCACCGGGGA
CCGGGTGCGGATCTTCGCCGACGGCCCGCTGGCCGGCAACGTCGAGGTGACCGGCCGGATCAAGGACGTCATCCACCGCG
GCGGTGAGACGGTTTCGGCGACCGACCTCGAGGACCATCTGCTGACCCACCCCGCGATCTATGCGGCGGCCGCCGTCGCG
CTACCCGACGACTATCTCGGTGAGAAGATCTGCGCCGCAGTGGTGTTCCGCGGCAAGCAGCTCACGCTCGCCGAACTCAA
CGCATTCCTCGACGAACGCGGGGCGTCCACTCACGCCCGGCCCGACGTGCTGGCTGCGATGCCGTCGCTGCCGCTGACCG
CGGTCGGCAAGGTCGACAAGAAGAAGCTCGTCGAGCAGCTGAGCGGGTGA

Protein sequence : 
MSTGFQHVHSDLTDGFVPFPEDRAEQYRRAGYWTGRPLESLLLDAAHRRPDHPAVVDVDGSLTFAELTARADTVAAALAG
LGIRPGDRVLLQLPNSVRFAVAFFGLLRAGAVPVMCLPGHRTAELGHFADVSGAVALIVPDEVGGFDYREMAAQLVADRP
TLRHVLVDGDPGPFLSWAALIDSGGVAPEIGPVDTSLPALLLVSGGTTGLPKLIPRTHDDYVYTAVSSAQACHFTPDDVY
LVALPAGHNFPLACPGMLGAMTVGATTVFTADPSPEEAFALIDKHQVTVTGLVNALGKLWAQACDWEPVLPTSLRLVQVG
GSRMSPEEARFILDLLTPGLSQIFGMAEGMLNFTRPGDPLDVVVHTQGRPVSPHDEMRVVDESGVEVAPGEEGELLVRGP
NTLNGYYRADEANARCFSPDGFYRTGDRVRIFADGPLAGNVEVTGRIKDVIHRGGETVSATDLEDHLLTHPAIYAAAAVA
LPDDYLGEKICAAVVFRGKQLTLAELNAFLDERGASTHARPDVLAAMPSLPLTAVGKVDKKKLVEQLSG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 3e-91 44
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-91 44
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-91 44
ybtE CAA21394.1 - Virulence HPI Protein 3e-91 44
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 5e-91 44
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-91 44
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-91 44
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 4e-91 44
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-91 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mjls_3482 YP_001071751.1 AMP-dependent synthetase and ligase VFG1817 Protein 2e-172 67
Mjls_3482 YP_001071751.1 AMP-dependent synthetase and ligase VFG0168 Protein 3e-86 42