Gene Information

Name : Mjls_3058 (Mjls_3058)
Accession : YP_001071328.1
Strain : Mycobacterium sp. JLS
Genome accession: NC_009077
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 3193875 - 3195293 bp
Length : 1419 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
GTGAATAGACGCGGGAAGATCGTCTGTACCCTCGGTCCGGCCACCGGCTCCGACGACGCCGTCCGGAAGCTGGTGGAGGC
CGGGATGGATGTCGCGCGGCTCAACTTCAGCCACGGCGACTACCCCGATCACGAAGCCAACTACAAGCGGGTCCGCGCGG
CCTCCGACCACACCGGACGCGCCGTCGGCATCCTCGCCGACCTGCAGGGTCCGAAGATCCGGCTGGGCCGCTTCGCCGAC
GGCCCGACCGTATGGGCCGAGGGCGAGACCGTCCGGATCACCGTCGACGACGTCGAGGGCACCCACGACCGCGTGTCGAC
CACCTACAAACGGTTGGCAGAGGACGCCACCCCCGGCGACCGGGTCCTCGTCGACGACGGCAACGTCGCGCTGGTGGTCA
ACGCCATCGAGGGCAACGACGTCGTCTGCGAGGTCACCGAGGGTGGCCGGGTCAGCAACAACAAGGGCATGTCGCTGCCC
GGGATGAACGTCTCGGCGCCCGCGCTGTCGGAGAAGGACATCGAGGACCTCGAGTTCGCGGTGCGCCTCGGTGTCGACCT
GGTCGCGCTGTCGTTCGTGCGGTCCCCGGCCGACGTCGAACTCGTGCACGAGGTGATGGACCGCGTGGGGCGGCGGGTCC
CGGTGATCGCCAAACTGGAGAAACCGGAGGCGATCGACAACCTCGAGGCGATCGTGCTGGCTTTCGACGCGATCATGGTC
GCCCGTGGCGATCTCGGCGTGGAACTGCCGCTCGAAGAGGTCCCGCTGGTGCAGAAGCGCGCCATCCAGATGGCCCGCGA
GAACGCCAAACCCGTCATCGTCGCCACGCAGATGCTGGAGTCGATGATCGAAAACTCCCGGCCCACCCGCGCCGAGGCAT
CCGACGTCGCCAACGCGGTGCTCGACGGCGCGGACGCGGTCATGCTCTCGGGTGAGACATCGGTGGGCAAGTATCCGCTC
GAGGCCGTGCGGACGATGGCGCGCATCATCATCGCCGTCGAGGAGAACTCCGTCGTAGTCCCGCCGCTGACCCACGTCCC
GCGCACCAAGCGCGGCGTGATCTCCTACGCCGCCCGCGACATCGGGGAGCGGTTGGACGCCAAGGCGCTCGTCGCGTTCA
CCCAGTCCGGGGACACCGTGCGGCGTCTCGCGCGGCTGCACACGCCGCTGCCCGTGCTCGCGTTCACCGCGCTGCCCGAG
GTGCGCAGCCAACTGGCCTTGACCTGGGGCACCGAAACGTTCATCGTGCCGCAGATCGGCACCACCGACGGCATGATCCG
CCAGGTCGACAAGTCGCTGCTCGAACTCGGCCGCTACAAGCGGGGCGATCTGGTGGTCATCGTCGCGGGTGCGCCGCCGG
GCACAGTAGGCTCCACGAATCTGATCCACGTGCACCGGATCGGGGAGGACGACGTCTAG

Protein sequence :
MNRRGKIVCTLGPATGSDDAVRKLVEAGMDVARLNFSHGDYPDHEANYKRVRAASDHTGRAVGILADLQGPKIRLGRFAD
GPTVWAEGETVRITVDDVEGTHDRVSTTYKRLAEDATPGDRVLVDDGNVALVVNAIEGNDVVCEVTEGGRVSNNKGMSLP
GMNVSAPALSEKDIEDLEFAVRLGVDLVALSFVRSPADVELVHEVMDRVGRRVPVIAKLEKPEAIDNLEAIVLAFDAIMV
ARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLESMIENSRPTRAEASDVANAVLDGADAVMLSGETSVGKYPL
EAVRTMARIIIAVEENSVVVPPLTHVPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPVLAFTALPE
VRSQLALTWGTETFIVPQIGTTDGMIRQVDKSLLELGRYKRGDLVVIVAGAPPGTVGSTNLIHVHRIGEDDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-75 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 6e-75 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-75 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-75 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mjls_3058 YP_001071328.1 pyruvate kinase VFG0479 Protein 1e-75 43