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Name : lysS (Mjls_2998) Accession : YP_001071268.1 Strain : Mycobacterium sp. JLS Genome accession: NC_009077 Putative virulence/resistance : Unknown Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 3127563 - 3130898 bp Length : 3336 bp Strand : + Note : catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA DNA sequence : ATGACGCTCACCAGTCCGCCGAGGACGCGCGCCGACTCCCGCCACTCCTGGGTTCCCGCGGCCGCCGGGTGGACCGTCGG CGTCATCGCCACCCTCTCGCTCATCGCGAGCGTCTCACCGCTGGTCCGGTGGATCATCCGGGTGCCGCGAGAGTTCGTCA ACGACTACATCTTCAACTTCCCCGACACCAGCTTCGCCTGGGCGTTCGTGCTGGCGCTGCTGGCGGGCGCGCTGGCCGCC CGCAAACGCATCGCCTGGTGGATTCTGCTGCTGTACATGGTCGCCGCGGTCGGCTGGAACGTCGCCGATCTGCTGACCGG TGACGAATCGGTCGTCGAGGAGATGGGCGAGGTCATCGGCCTCGCCTTCCACCTTGCGGCCGTGGCCTTCCTGCTGTTGG CCCGCCCGCTGTTCTGGGCCCGCGTGCGGCGCGGCGCCCTGTTCAAGGCGGCCGGTGTGCTGGCCGCCGGAATGGCGGTC GGCGTGCTCGTCGGCTGGGGTCTGCTCGAACTGTTCCCCGGCGACCTCGAACGCGACTACCGCTTGGCATACGCGGCGAA CCGGGTGTTCGCGTTCGCCGGCGTCGACCCCGACGCGTTCGACGGACAACACCCACACGTGGTCGTCAACGCCCTGCTCG GGTTGTTCGGCGCGCTGGCGTTGATGGCCGCGGCGATCGTGCTGTTCCAGTCGCAGCGCTCCGAGAACGCGCTCACCGGC GAAGACGAATCGGCCATCCGCGGTCTGCTCGAGCTCTACGGCAAGAACGACTCGCTGGGGTATTTCGCCACCCGGCGGGA CAAGTCCGTGGTGTTCGCACCGAACGGACGCGCCGCGATCACCTACCGGGTCGAGGTGGGGGTCTGCCTGGCCAGCGGTG ACCCGGTCGGCGACCCGAAAGCCTGGCCGCAGGCGATCGACGCGTGGCTGGCGCTGTGCGGGACGTACGGCTGGGCACCG GGTGTCATGGGTGCCAGCGTGGGCGGGGCCGAGGCGTTCCGGGCCGCCGGACTCAGCGCGATCCAACTGGGCGACGAGGC CATCCTGCATCCGGACAGCTTCCGGCTCTCCGGGCCGGACATGCGGGCGGTGCGCCAGGCCGTCACGCGGGCCCGCCGCG CCGGGGTGACCGTGCGGATCCGCAGACACCGGGAGCTCTCACCCGAACAGATGGCCGAGGTGATCGCCCACGCCGACGCC TGGCGCGACACCGAGACAGAACGCGGCTTCTCGATGGCGCTCGGCCGCCTCGGCGATCCCGCCGACAGCGACTGCCTGCT GGTGGAGGCCGTCCAGGGCGAGACCGGGGGCGAGCGAAGCGACCCGGGGAGTGGCACCGTCGTGGCCATGTTGTCGCTGG TGCCGTGGGGCAGCAACGGCGCCTCCCTCGACGTGATGCGGCGTTCCCCGCAGTCACCCAACGGCACCATCGAGTTGATG GTCAGCGAGCTGTGCATGCAGGCCGAGGACATCGGCGTCACCCGCATCTCCCTGAACTTCGCGATGTTCCGGTCGGCGTT CGAGCAGGGCGCGCAACTCGGCGCCGGACCCGTGGCCCGGCTGTGGCGCTGGCTGCTGGTCTTCTTCTCCCGGTGGTGGC AGCTGGAGACGCTGTACCGCTCGAACATGAAATACCAACCGCAGTGGGTGCCGCGCTACGCCTGCTACGAGGACGCGCGC CTCATCCCCCGCGTCGGGGTGGCATCGGTGATCGCCGAGGGCTTCCTGGTGCTGCCGTTCTCGCGGCGCAACAAACAACA CACCGGCCACCACACGTCCGCACCGCAGGACCTGGTCGCCAGCGGCGTGCTCCACCACGACGGCACCGCACCCGACATGT CCGGGTTGCGCACCGACACCGCCGACGACGAACCGCCCCGGCTGCCCGAGCAGGTGCGGGTCCGGATGGCGAAACTCAAG GCGCTGCAGGCCGACGGCGTCGACGCCTATCCGGTCGGCCGGCCACCCAGCCACACCGCGGCGGCTGCCGTCGACTCCCC CGACGACGTCGAACTCGATGTCGCCGGCCGGGTGCTGCGCATCCGCGACTACGGCGGTGTGCTGTTCGCCCAGTTACGGG ACTGGTCGGGTGAAGTGCAACTGCTGCTGGACAATTCGACACTCGAGCAGGGCAGCACCGCCGACTTCACCGCGGCCATC GACCTCGGCGACCTCATCGAGGCGACCGGCACCATGGGCTACAGCAAGAACGGGACCCGCTCGCTGCTGGTGCGGCACTG GCGGCTCACCGGTAAATGCCTGCGTCCCCTGCCGGACAAGTGGAAGGGCCTGACCGATCAGGAGGCCCGCGTCCGGGCCC GCTACGTCGACCTGGCGGTCAACACCGAGGCGCGGGATCTGATCCGGGCCCGCAGCGGCGTGCTGCACGCGATCCGGGAC ACGCTGTACCACAAGGGTTTCCTCGAGGTCGAGACCCCGATCCTGCAGCAGATCCACGGCGGCGCCAACGCACGGCCGTT CCTGACCCACATCAACGCCTACGACCTGGACCTGTATCTGCGCATCGCGCCCGAGCTGTATCTCAAGCGGCTCTGCGTCG GTGGGGTGGAGCGGGTCTTCGAACTCGGCCGCGCGTTCCGCAACGAAGGCGTCGACTTCTCCCACAACCCCGAATTCACA CTGCTGGAGGCGTATCAGGCGCACGCCGACTACCACGTGTGGATCGACGGGTGCCGTGAACTCATCCAGAACGCCGCGAT GGCCGCCAACGGTGAGCACGTGTTCCTCCGTCCGCGTGACGACGGCGTCCTCGAACCCGTCGACATCTCCGGACCGTGGA CGGTCAAGACGGTGCACGATGCGGTGTCCGAGGCGCTCGGCGAACACATCGACGCCGCCACGGAACTGCCGACGCTGCGC AAGCTGGCCGACGCGGCGGGCATCCCCTATCTGACCCACTGGGACGAGGGGGCGGTGGTGCTCGAGATGTACGAGCACCT GGTCGAGGACCGCACCGAGAAGCCGACGTTCTACAAGGACTTCCCGACGTCCGTATCCCCCTTGACGCGCCCGCATCGCA GCATTGCCGGCGTCGCCGAACGGTGGGACCTCGTCGCCTGGGGTGTCGAATTGGGCACCGCCTACAGCGAACTCACCGAT CCGGTGGAGCAGCGTCGTCGACTGCAGGCGCAGTCGCTGCTCGCCGCGGGCGGTGATCCGGAGGCGATGGAACTCGACGA GGACTTCCTGCAGGCCATGGAGTACGCGATGCCGCCCACCGGTGGGCTGGGCATGGGTGTCGATCGGGTGGTCATGCTGA TCACCGGCCGCAGCATCCGGGAGACGCTTCCGTTCCCGTTGGCCAGACCACGTTGA Protein sequence : MTLTSPPRTRADSRHSWVPAAAGWTVGVIATLSLIASVSPLVRWIIRVPREFVNDYIFNFPDTSFAWAFVLALLAGALAA RKRIAWWILLLYMVAAVGWNVADLLTGDESVVEEMGEVIGLAFHLAAVAFLLLARPLFWARVRRGALFKAAGVLAAGMAV GVLVGWGLLELFPGDLERDYRLAYAANRVFAFAGVDPDAFDGQHPHVVVNALLGLFGALALMAAAIVLFQSQRSENALTG EDESAIRGLLELYGKNDSLGYFATRRDKSVVFAPNGRAAITYRVEVGVCLASGDPVGDPKAWPQAIDAWLALCGTYGWAP GVMGASVGGAEAFRAAGLSAIQLGDEAILHPDSFRLSGPDMRAVRQAVTRARRAGVTVRIRRHRELSPEQMAEVIAHADA WRDTETERGFSMALGRLGDPADSDCLLVEAVQGETGGERSDPGSGTVVAMLSLVPWGSNGASLDVMRRSPQSPNGTIELM VSELCMQAEDIGVTRISLNFAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPQWVPRYACYEDAR LIPRVGVASVIAEGFLVLPFSRRNKQHTGHHTSAPQDLVASGVLHHDGTAPDMSGLRTDTADDEPPRLPEQVRVRMAKLK ALQADGVDAYPVGRPPSHTAAAAVDSPDDVELDVAGRVLRIRDYGGVLFAQLRDWSGEVQLLLDNSTLEQGSTADFTAAI DLGDLIEATGTMGYSKNGTRSLLVRHWRLTGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTEARDLIRARSGVLHAIRD TLYHKGFLEVETPILQQIHGGANARPFLTHINAYDLDLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFT LLEAYQAHADYHVWIDGCRELIQNAAMAANGEHVFLRPRDDGVLEPVDISGPWTVKTVHDAVSEALGEHIDAATELPTLR KLADAAGIPYLTHWDEGAVVLEMYEHLVEDRTEKPTFYKDFPTSVSPLTRPHRSIAGVAERWDLVAWGVELGTAYSELTD PVEQRRRLQAQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLARPR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| lysS1 | YP_005686365.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-151 | 45 |
| lysS1 | YP_005682181.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 4e-151 | 45 |
| lysS1 | YP_005684273.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-151 | 45 |
| lysX | YP_003784331.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 1e-151 | 45 |
