Gene Information

Name : Mjls_2454 (Mjls_2454)
Accession : YP_001070729.1
Strain : Mycobacterium sp. JLS
Genome accession: NC_009077
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 2566885 - 2568978 bp
Length : 2094 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
GTGACCACCGTCGACGACATCGCGACGCTGACCCAACCCCACCACCCCGACGACTGGTCCGAGTTGGACTCCGTCGCGGT
CGACACCGTGCGGGTGCTGGCGGCGGATGCCGTGCAGAAGGTCGGCAACGGCCATCCCGGTACGGCGATGAGCCTGGCGC
CGCTGGCGTACACGCTGTTCCAGCGGACCATGCGGCACGACCCCAGCGATGTGCACTGGCTGGGCCGGGACCGGTTCGTC
CTGTCCTGCGGTCATTCGAGCCTGACGCTCTACATCCAGCTCTACCTGGGCGGGTTCGGTCTCGAGCTCGAGGACATCCA
GGCGCTGCGGACCTTCAAGTCGAAGACCCCGGGCCATCCCGAGTTCCGGCACACCAAGGGTGTGGAGATCACCACCGGCC
CGCTCGGTCAGGGCCTCGCCTCGGCCGTGGGTATGGCGATGGCGGCGCGCTACGAGCGCGGGCTGTTCGACCCGGACGCC
GCGCCGGGCACCAGCCCGTTCGACCACCACATCTACGTGATCGCCTCCGACGGCGACATCGAAGAGGGTGTGACCAGCGA
GGCGTCGTCGCTGGCGGGTACCCAGCAGCTGGGCAACCTCATCGTCTTCTACGACCAGAACCAGATCTCCATCGAGCACG
ACACGAACATCGCGCTGTCGGAGAATGTCGCCGACCGCTACCGCGCCTACGGCTGGCACGTCCAGGAGGTCGAGGGCGGC
GAGAACGTCGTCGGAATCGAAGAAGCCATCGAGGCCGCCAAGGCGGTCACGGACCGCCCGTCCTTCATCGCGGTGCGCAC
GATCATCGGCTATCCGGCGCCGAACAAGATGAACACCGGCGGCGTGCACGGCTCGGCGCTCGGTGACGACGAGGTCGCGG
CGGTCAAGGAGGTTCTCGGCTTCGATCCGGACAAGACGTTCGAGGTGCGCGACGAGGTCATCGAGCACACCCGCAAGCTC
GTCCAGCGGGGCCGCGAAGCCCACGAGAAGTGGCAGCCCGAGTTCGACGCCTGGGCCGAGCGCGAACCCGAGCGCAAGAA
GCTGCTCGACCGGCTGCTCGCCCAGGAGCTGCCGGACGGCTGGGACGCCGATCTGACGTACTGGGAGCCGGGCAGCAAGG
CGGTCGCCACCCGCGCCGCGTTCGGCCAGGTGCTCAACGACGTCGCGCCGAAGCTGCCCGAATTGTGGGGCGGTTCGGCC
GATTTGGCCGGTAGCAACAACACGACCATCAAGGGCGTGAAATCGTTCGGCCCGCCGTCGATCTCGACCGACGACTTCAC
CGCCGACTGGTACGGCCGGGTGCTGCACTTCGGTATCCGCGAACACGCGATGGGCTCGATCCTGTCGGGCATCGTGCTGC
ACGGCCCGACGCGCGCCTTCGGCGGGACGTTCCTGCAGTTCTCCGACTACATGCGGCCGGCGGTGCGGTTGGCCTCGCTG
ATGGACATCGACACCATCTACATCTGGACCCACGATTCGATCGGTCTCGGCGAGGACGGCCCCACGCACCAGCCGATCGA
ACATCTCGCCGCGCTGCGGGCGATCCCTAACCTGTCGGTGGTCCGGCCGGGTGACCCGAACGAGACGGCCTACGCCTGGC
GCAGCATCCTGGCCCGCGGCAACGGCAGCGGCCCGGTCGGTTTCATCCTGACCCGACAGGGCATCCCGGTGCTGGAGGGC
ACCGACTCCGACGGCGTCGCCCGCGGCGGATACGTCCTCGGCGGCGGGAATCCCTCCGATGACGCCGACGTCATCATCAT
CGCGACCGGATCCGAACTCCAGCTCGCGGTGGAGGCGAAGAAGCTCCTCGCCGAGAAGGACCTCACCGCATACGTGGTGT
CCATGCCGTGCGTGGAGTGGTTCGAGTCGCAGCCGAAGGAATACCGCGACAGCGTGCTGCCTCCCAACGTCTCCGCGCGC
GTCGCAGTGGAGGCCGCCGTCGCCCAGAGCTGGTACAAGCTCGTCGGCGACACCGGCGAGATCGTCTCCATCGAGCACTA
CGGGGAGTCCGCCGACGACAAGACGTTGTTCCGCGAGTTCGGCTTCACCGCCGAGGCCGTGGCCGCCGCCGCGGAGCGCA
CCATAAACAACTAA

Protein sequence :
MTTVDDIATLTQPHHPDDWSELDSVAVDTVRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRTMRHDPSDVHWLGRDRFV
LSCGHSSLTLYIQLYLGGFGLELEDIQALRTFKSKTPGHPEFRHTKGVEITTGPLGQGLASAVGMAMAARYERGLFDPDA
APGTSPFDHHIYVIASDGDIEEGVTSEASSLAGTQQLGNLIVFYDQNQISIEHDTNIALSENVADRYRAYGWHVQEVEGG
ENVVGIEEAIEAAKAVTDRPSFIAVRTIIGYPAPNKMNTGGVHGSALGDDEVAAVKEVLGFDPDKTFEVRDEVIEHTRKL
VQRGREAHEKWQPEFDAWAEREPERKKLLDRLLAQELPDGWDADLTYWEPGSKAVATRAAFGQVLNDVAPKLPELWGGSA
DLAGSNNTTIKGVKSFGPPSISTDDFTADWYGRVLHFGIREHAMGSILSGIVLHGPTRAFGGTFLQFSDYMRPAVRLASL
MDIDTIYIWTHDSIGLGEDGPTHQPIEHLAALRAIPNLSVVRPGDPNETAYAWRSILARGNGSGPVGFILTRQGIPVLEG
TDSDGVARGGYVLGGGNPSDDADVIIIATGSELQLAVEAKKLLAEKDLTAYVVSMPCVEWFESQPKEYRDSVLPPNVSAR
VAVEAAVAQSWYKLVGDTGEIVSIEHYGESADDKTLFREFGFTAEAVAAAAERTINN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 1e-107 42
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 3e-108 41