Gene Information

Name : cadA (BURPS1106A_4019)
Accession : YP_001068238.1
Strain :
Genome accession: NC_009076
Putative virulence/resistance : Resistance
Product : cadmium-translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.3.-
Position : 3922547 - 3925045 bp
Length : 2499 bp
Strand : -
Note : identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525

DNA sequence :
ATGACCGAGGCCACCCGGGCCGAAAACCGGCCGCGAACGCCAGAAGCCGATCGCGGCGGCGCGCAGTCGGGCGATGCGCG
CACATCGGCGCGCGCCGCTGGCTGCTGCTCGCACCATCACCCGCATGGCGAGGTCGAAACGCAGGCGAATCTCGCGGTTC
AGTCAAGCAATCGCGATTCGAGCGACCACGCACATGCACCCCATTCGCATGCGAACGGCGACCATCCGCACGACCACGAC
CACGACCACGACCACGACCACGACCACGACCACGACCACGACGGCGCGGCGTGCTGCGCGCCCGCCCCCGTCGCGTTCGC
GCCGTTGCCCGGCGCGCGAAAGGCCGCCGGCGGCCGTGTGCGCTCGGCGTTCCGGATCATGCAGATGGACTGCCCGACCG
AGGAGACACTGATCCGCAAGAAGCTGGGCGCGATGTCCGAAGTCGCGGCGCTCGAATTCAACCTGATGCAGCGGATGCTC
GCGGTCGAGCACGTGCCGGGCGCGGAAGCCGGCATCGCCGCCGCGATCCGCTCGCTCGGCATGACGCCCGAACAGGCGGA
CGCCGGCGCGTCGGGCCGTGGCGCGTTGCCCGCGCCGGCCGACGCGCCGCGCCCGTGGTGGCCGCTCGCGGTCGCGGGCG
TCGCGGCGGCGGCGTCGGAAGCGGCCACGTGGCTGCAACTGCCGGTATGGCTCGCCGCCGCGCTCGCGCTCGCCGCGGTC
GCGACCTGCGGCCTCGGCACGTATCGCAAGGGCTGGATCGCGCTCATGAACGGCAACCTGAACATCAACGCGCTGATGAG
CATCGCGGTGACGGGCGCGATGGCGATTGGCCAGTGGCCCGAGGCCGCGATGGTGATGGTGCTCTTCACCGTCGCCGAAT
TGATCGAGGCGCGCTCGCTCGACCGTGCGCGCAACGCGATCCAGAGCCTGATGCGCCTCGCGCCCGACACCGTGACGCTC
AGGCAGCCCGACGGCACGTGGCAGCCGGTCGACGCCGCGCAGGTCGCGCTCGGTGCGATCGTGCGCGTGAAGCCCGGCGA
GCGCATCGGCCTCGACGGCGAGATCGTTGCCGGCCGCTCGACCGTCAACCAGGCGCCGATCACGGGCGAGAGCCTGCCCG
TCGAGAAAACCGAGGGCGACGCGGTGTACGCGGGCACGATCAACGAAGCCGGCTCGTTCGAATATCGGGTGACGGCGGTC
GCGAGCAACACGACGCTCGCGCGGATCATCCATGCGGTCGAGGAGGCGCAGGGCGCGAAGGCGCCGACGCAGCGCTTCGT
CGACAGCTTCGCGCGCGTCTACACGCCGATCGTGTTCGCGATCGCGCTCGTCGTCGCGATCGCGCCGCCGCTCGTGCTCG
ACGGCGCATGGCGCGACTGGATCTATCGCGCGCTCGTGCTGCTCGTGATCGCGTGCCCATGCGCGCTCGTGATCTCGACG
CCCGTGACGATCGTATCGGGGCTCGCGGCGGCCGCGCGGCGCGGGATTCTCGTGAAGGGCGGCGTGTACCTCGAGCAGGG
GCGCCGCCTCGCGTGGCTCGCGCTCGACAAGACGGGCACGATCACGCGCGGCAAGCCGGTGCAGACCGATTTCGAGATGC
GCGCAGCCGACGTCGACGCCGCGCTCGTGCGGGGGCTCGCCGCGAGCCTCGCCGCGCGCTCGGATCACCCGGTTTCGCAG
GCGGTCGCGGCGGCGAGCGCGGCTCAAGCCGGCGCGGGCGGCGTCCCGCGCGCGAAGCCCGCGTCGTTCGCCGACGTCGC
CGATTTCGAGGCGATTCCCGGCCGCGGCGTGCGCGGCAAGATCGACGGCGTGCCGTACTGGCTCGGCAATCATCGCCTCG
TCGAGGAGCTCGACTGCTGCACGAGCGCGCTCGAAGCGCGTCTCGACGAGCTCGAGCGGCAGGGCAAGACGGTCGTGATG
CTGATCGACGGCGCGCGCGTGCTCGGCCTCTTCGCGGTGGCCGACACGGTGAAGGACACGAGCCGCGCGGCGGTTGCCGA
GCTGCACGCGCTCGGCATCAAGACCGCGATGCTGACGGGCGACAACCCGCACACCGCGCAAGCGATCGCGCAGCAGGTCG
GCATCGACGACGCGCGCGGCAACCAACTGCCGCAGGACAAGCTCGCCGCCGTCGAAGCGCTCGCGGCGGGCGGCCGCGCG
GTCGGCATGGTCGGCGACGGGATCAACGACGCGCCGGCGCTCGCGCGCGCCGACATCGGCTTCGCGATGGGCGCGATGGG
CACCGATACCGCGATCGAGACGGCCGACGTCGCGCTGATGGACGACGACCTGCGCAAGATCCCGGCGTTCGTGCGGCTGT
CGCGCGCGACGCATCGCGTGCTCGTGCAGAACATCGCGTTCGCGCTCGCCGTGAAGGCGGTGTTCGTCGGCCTCACGGTC
GCGGGGATGGGCACGATGTGGATGGCGGTGTTCGCCGACGCGGGCGCGAGCCTCATCGTCGTCGGCAACGGCTTGCGGCT
GTTGCGCCGCGGCCAATGA

Protein sequence :
MTEATRAENRPRTPEADRGGAQSGDARTSARAAGCCSHHHPHGEVETQANLAVQSSNRDSSDHAHAPHSHANGDHPHDHD
HDHDHDHDHDHDHDGAACCAPAPVAFAPLPGARKAAGGRVRSAFRIMQMDCPTEETLIRKKLGAMSEVAALEFNLMQRML
AVEHVPGAEAGIAAAIRSLGMTPEQADAGASGRGALPAPADAPRPWWPLAVAGVAAAASEAATWLQLPVWLAAALALAAV
ATCGLGTYRKGWIALMNGNLNINALMSIAVTGAMAIGQWPEAAMVMVLFTVAELIEARSLDRARNAIQSLMRLAPDTVTL
RQPDGTWQPVDAAQVALGAIVRVKPGERIGLDGEIVAGRSTVNQAPITGESLPVEKTEGDAVYAGTINEAGSFEYRVTAV
ASNTTLARIIHAVEEAQGAKAPTQRFVDSFARVYTPIVFAIALVVAIAPPLVLDGAWRDWIYRALVLLVIACPCALVIST
PVTIVSGLAAAARRGILVKGGVYLEQGRRLAWLALDKTGTITRGKPVQTDFEMRAADVDAALVRGLAASLAARSDHPVSQ
AVAAASAAQAGAGGVPRAKPASFADVADFEAIPGRGVRGKIDGVPYWLGNHRLVEELDCCTSALEARLDELERQGKTVVM
LIDGARVLGLFAVADTVKDTSRAAVAELHALGIKTAMLTGDNPHTAQAIAQQVGIDDARGNQLPQDKLAAVEALAAGGRA
VGMVGDGINDAPALARADIGFAMGAMGTDTAIETADVALMDDDLRKIPAFVRLSRATHRVLVQNIAFALAVKAVFVGLTV
AGMGTMWMAVFADAGASLIVVGNGLRLLRRGQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 4e-116 46
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 4e-116 46
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-115 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_001068238.1 cadmium-translocating P-type ATPase BAC0298 Protein 0.0 66