Gene Information

Name : spaP (BURPS668_A2167)
Accession : YP_001063161.1
Strain :
Genome accession: NC_009075
Putative virulence/resistance : Virulence
Product : surface presentation of antigens protein SpaP
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4790
EC number : -
Position : 2104066 - 2104746 bp
Length : 681 bp
Strand : -
Note : part of a type III secretory system probably involved in invasion into eukaryotic cells

DNA sequence : 
ATGGCGAATAACGAAATCGCGCTGATCGTCCTGCTGACGGCGGCCACGCTCGTGCCGTTCGTCGTCGCGGCGGGCTCGTG
CTTCATCAAGTTCTCGATCGTGCTCGTGCTCGTGCGCAACGCGCTCGGCATCCAGCAGGTGCCGTCGAATCTCGCGCTCA
ACAGCATCGCGCTCATCATGTCGCTGTTCGTGATGATGCCCGTCGCGCAGAGCGCGTACCGATATCTGCAGCACCATCCG
CTCGACGTGATGAGCGGCGCGTCGGTCAACGAGTTCATCGACGGCGGGCTCGGCGATTACAAGCGCTATCTGACGCGCTA
CTCGGACCCGGAACTCGTGCGCTTCTTCGAGCGCGCGCAGACCGCGCGCCTGAAGGGCGACGACGCCGACGCCGCCGATG
CGGACGACGCGCCCGACGGCCTCGACAATTCGTTGTTCTCGCTGCTGCCCGCGTATGCGCTCACCGAGATCAAGAGCGCG
TTCAAGATCGGCTTCTACCTGTACCTGCCGTTTCTCGTCGTCGACATGGTGGTGTCGAGCGTGCTGCTCGCGCTCGGGAT
GATGATGATGAGCCCGGTGACGATCTCGGTGCCGATCAAGCTGATCCTGTTCGTCGCGATGGACGGCTGGACGCTGATCT
GCAAGGGCCTGATCGAGCAGTACCTGAACCTGATGCAATGA

Protein sequence : 
MANNEIALIVLLTAATLVPFVVAAGSCFIKFSIVLVLVRNALGIQQVPSNLALNSIALIMSLFVMMPVAQSAYRYLQHHP
LDVMSGASVNEFIDGGLGDYKRYLTRYSDPELVRFFERAQTARLKGDDADAADADDAPDGLDNSLFSLLPAYALTEIKSA
FKIGFYLYLPFLVVDMVVSSVLLALGMMMMSPVTISVPIKLILFVAMDGWTLICKGLIEQYLNLMQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
spaP NP_311752.1 surface presentation of antigens protein SpaP Not tested LIM Protein 6e-53 62
epaP AAZ31293.1 EpaP Virulence ETT2 Protein 1e-51 61
spaP YP_217809.1 surface presentation of antigens protein SpaP Virulence SPI-1 Protein 1e-50 60
spaP NP_461811.1 surface presentation of antigens protein SpaP Virulence SPI-1 Protein 1e-50 60
spaP NP_457284.1 secretory protein (associated with virulence) Virulence SPI-1 Protein 1e-50 60
spaP NP_806493.1 surface presentation of antigens protein SpaP Virulence SPI-1 Protein 1e-50 60
ysaR AAS66846.1 YsaR Not tested SSR-1 Protein 2e-49 60
spaP AAS66865.1 SpaP Not tested SSR-2 Protein 8e-52 57
escR AAK26700.1 EscR Virulence LEE Protein 1e-30 42
escR AAL57527.1 EscR Virulence LEE Protein 1e-30 42
escR CAC81847.1 EscR protein Virulence LEE II Protein 1e-30 42
escR CAI43889.1 EscR protein Virulence LEE Protein 1e-30 42
escR YP_003223490.1 T3SS structure protein EscR Virulence LEE Protein 2e-30 42
escR YP_003232138.1 type III secretion system protein Virulence LEE Protein 2e-30 42
escR YP_003236103.1 T3SS structure protein EscR Virulence LEE Protein 2e-30 41
escR NP_290283.1 type III secretion system protein Virulence LEE Protein 2e-30 41
escR AAC38369.1 EscR Virulence LEE Protein 7e-30 41
escR AAC31528.1 L0049 Virulence LEE Protein 1e-30 41
escR ACU09473.1 type III secretion system protein EscR Virulence LEE Protein 1e-30 41
ECs4583 NP_312610.1 type III secretion system protein Virulence LEE Protein 1e-30 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
spaP YP_001063161.1 surface presentation of antigens protein SpaP VFG2455 Protein 5e-83 100
spaP YP_001063161.1 surface presentation of antigens protein SpaP VFG1773 Protein 2e-56 63
spaP YP_001063161.1 surface presentation of antigens protein SpaP VFG1012 Protein 2e-51 60
spaP YP_001063161.1 surface presentation of antigens protein SpaP VFG0551 Protein 5e-51 60
spaP YP_001063161.1 surface presentation of antigens protein SpaP VFG0394 Protein 3e-32 43
spaP YP_001063161.1 surface presentation of antigens protein SpaP VFG0188 Protein 1e-32 41
spaP YP_001063161.1 surface presentation of antigens protein SpaP VFG0827 Protein 7e-31 41
spaP YP_001063161.1 surface presentation of antigens protein SpaP VFG0715 Protein 4e-30 41