Gene Information

Name : hemC (BURPS668_1071)
Accession : YP_001058121.1
Strain :
Genome accession: NC_009074
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1049698 - 1050687 bp
Length : 990 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAACTCCGAGACTCTTCCGGCCGAGCTGCCCGCGACGCTGACGATCGCGTCGCGCGAGAGCCGCCTCGCCATGTGGCA
AGCCGAGCATGTGCGTGATGCGCTGCGCAAATTATATCCAGCTTGTGACGTGAAAATCCTCGGGATGACGACGCGCGGCG
ATCAAATTCTCGATCGCACGCTATCGAAGGTCGGCGGCAAGGGTCTGTTCGTCAAGGAGCTCGAGAGCGCGCTTGCCGAC
GGCCGCGCGGATCTCGCCGTGCATTCGCTGAAGGACGTGCCGATGGTGCTGCCCGAAGGCTTCGCGCTCGCGGCGGTGAT
GAGCCGCGAGGATCCGCGCGACGCGTTCGTGTCGAACGATTACGCGTCGCTCGACGCGCTGCCGGCGGGCGCCGTCGTCG
GCACGTCGAGCCTGCGCCGCGAGGCGATGCTGCGCGCGCGCCATCCGCGGCTCGACGTGCGGCCGCTGCGCGGCAATCTC
GACACGCGGCTCGCGAAGCTCGACCGCGGCGATTACGCGGCGATCATCCTCGCCGCCGCGGGCCTCAAGCGTCTCGGCCT
CGCCGCGCGGATCCGCGCGCTGCTCGACGTCGACGACAGCCTGCCCGCCGCGGGGCAGGGCGCGCTCGGCATCGAGATCG
CCGCGCGCCGCGCCGATGTCGCCGCGTGGCTCGCGCCGCTGCACGATCATGCGAGCGCGCTCGCGGTCGAGGCCGAACGC
GCGGTGTCGCGCGCGCTCGGCGGCAGTTGCGAGGTGCCGCTCGCCGCGCACGCGGTGTGGCGCGGCGGCGAGCTGCATCT
GACGGGCAGCGTGTCGACGACGGACGGCGCGCGCGTGCTCGCCGCGCATGCGCACGCACGCGCGGCGACGGCCGCCGATG
CGCTCGCGCTCGGCCGCAGGGTGTCCGACGCGCTCGAGCGGCAAGGCGCGCGCGCGATCGTCGACGCGCTCGTCGCGGCG
AGCGCGCAAGCGCAAAAGGGCGGCGCGTGA

Protein sequence :
MNSETLPAELPATLTIASRESRLAMWQAEHVRDALRKLYPACDVKILGMTTRGDQILDRTLSKVGGKGLFVKELESALAD
GRADLAVHSLKDVPMVLPEGFALAAVMSREDPRDAFVSNDYASLDALPAGAVVGTSSLRREAMLRARHPRLDVRPLRGNL
DTRLAKLDRGDYAAIILAAAGLKRLGLAARIRALLDVDDSLPAAGQGALGIEIAARRADVAAWLAPLHDHASALAVEAER
AVSRALGGSCEVPLAAHAVWRGGELHLTGSVSTTDGARVLAAHAHARAATAADALALGRRVSDALERQGARAIVDALVAA
SAQAQKGGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-51 55
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-51 55