Gene Information

Name : tktA (APL_0983)
Accession : YP_001053682.1
Strain : Actinobacillus pleuropneumoniae L20
Genome accession: NC_009053
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1136203 - 1138209 bp
Length : 2007 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGGCAGAACGTAAAGTATTAGCGAATGCAATTCGCTTTCTAAGTATGGATGCGGTACAAAAAGCTAATTCCGGTCACCC
GGGCGCCCCAATGGGGATGGCGGATATCGCAGAGGTATTATGGCGCGATTTTTTAAAACACAATCCGACCAATCCTAAGT
GGGCGGATCGCGACCGTTTCGTACTTTCAAACGGCCATGGTTCAATGTTAATTTATAGCTTATTACACTTAACGGGCTAT
GATCTTTCAATTGAAGATTTAAAACAATTCCGTCAATTACATTCTAAAACACCGGGTCACCCTGAATACGGTTATGCTCC
GGGTGTTGAAACTACGACCGGTCCGTTAGGTCAAGGTATCACTAATGCGGTCGGTATGGCGATTGCGGAAAAAACCTTAG
CCGCACAGTTTAACCGTGAAGGTCATAAAATCGTTGATCACTATACCTATGCGTTTTTAGGTGACGGTTGTTTAATGGAA
GGTATCTCACATGAAGCATGCTCATTAGCGGGTACTTTAGGCTTAGGCAAATTAATCGCTTTCTATGACGATAATAATAT
TTCAATCGACGGTCATGTGGACGGCTGGTTCTCTGATGATACCGCACAACGTTTTGAAGCATACGGTTGGCAAGTGATCC
GTAATGTGGACGGTCATGATGCGGAACAAATCAAATTTGCGATTGAAAATGCAAAAGCGGAGACCGAGCGTCCGACATTA
ATTATCTGTAAAACCATTATCGGTTACGGTTCTCCGAACAAATCGGCATCGCATGACTGCCACGGTGCGCCGTTAGGTAA
TGATGAAATCGCATTAACCCGTAAAGCACTCAACTGGGAATATGCGCCGTTTGAAATTCCGGCTGAAATCTATGCGGAAT
GGGATGCCAAAGCGCAAGGTGCGGTTGTAGAAAAAGAATGGAATGCTAAATTTGCGGCTTATGAAGCGGCGTATCCTGAA
TTAGCGGCGGAATTTAAACGTCGTATGGCGGGTGATTTACCGGCAAACTGGGAAGCGGAAAGTAAAGCGTTTATTGAAAA
ATTACAAGCAAATCCGGCGGCAATCGCAAGCCGTAAAGCATCACAAAATGCGATTGAAGCTTATGCGCATATCTTACCGG
AATTCTTAGGCGGTTCTGCCGACTTAGCAAGTTCTAACTTAACCTTATGGTCAGGTTCAAAACCAATCCGTGCGGATCAT
AACGTCGATGGTAACTACATCAACTACGGTGTACGTGAATTCGGTATGTCTGCAATTATGAACGGTATTGCATTACACGG
CGGTTTTATTCCTTACGGTGCAACATTCTTAATGTTCTATGAATATGCCCACAATGCGGTGCGTATGGCGGCATTAATGA
AACAACGCTCATTATTCGTTTATACACATGATTCTATCGGTTTAGGCGAAGACGGCCCGACTCACCAACCGGTAGAACAA
ACCGCATCATTACGTTTCATTCCGAACTTAGAAACATGGCGTCCGGCTGACCAAGTGGAATCTGCTGTTGCATGGAAAGC
AGCGGTTGAACGTAAAGACGGCCCGAGTGCATTAATCTTTACTCGCCAAAATCTTGCGCAACAAACACGTACGCCGGAAC
AATTGGCAAACGTTGCTCGCGGTGGTTATATCTTACGTGAATGCTGTCAAAAAGGCGGTTGTCCGGATTTAATTCTCATC
GCAACCGGCTCAGAAGTGGATTTAGCTATGAAAGCAGCTGAAGTATTAGATGCGGAAGGTACGAAAGTACGTGTTGTTTC
CATGCCAAGTACCAATGTATTCGACAAACAAGATGCCGCATATCGTGAAAGCGTATTACCAAGCTCAGTAACCAAACGTG
TAGCAATCGAAGCACAATTATCTGATTTCTGGTACAAATACGTTGGCTTTGAAGGGCGTATCGTCGGTATGAATAGCTTC
GGTGAGTCTGCGCCAGCGGATCAACTTTTCAAACTATTCGGTTTCACTGTTGATAACGTGGTAGCGAAAGCGAAAGAAAT
TTTATAA

Protein sequence :
MAERKVLANAIRFLSMDAVQKANSGHPGAPMGMADIAEVLWRDFLKHNPTNPKWADRDRFVLSNGHGSMLIYSLLHLTGY
DLSIEDLKQFRQLHSKTPGHPEYGYAPGVETTTGPLGQGITNAVGMAIAEKTLAAQFNREGHKIVDHYTYAFLGDGCLME
GISHEACSLAGTLGLGKLIAFYDDNNISIDGHVDGWFSDDTAQRFEAYGWQVIRNVDGHDAEQIKFAIENAKAETERPTL
IICKTIIGYGSPNKSASHDCHGAPLGNDEIALTRKALNWEYAPFEIPAEIYAEWDAKAQGAVVEKEWNAKFAAYEAAYPE
LAAEFKRRMAGDLPANWEAESKAFIEKLQANPAAIASRKASQNAIEAYAHILPEFLGGSADLASSNLTLWSGSKPIRADH
NVDGNYINYGVREFGMSAIMNGIALHGGFIPYGATFLMFYEYAHNAVRMAALMKQRSLFVYTHDSIGLGEDGPTHQPVEQ
TASLRFIPNLETWRPADQVESAVAWKAAVERKDGPSALIFTRQNLAQQTRTPEQLANVARGGYILRECCQKGGCPDLILI
ATGSEVDLAMKAAEVLDAEGTKVRVVSMPSTNVFDKQDAAYRESVLPSSVTKRVAIEAQLSDFWYKYVGFEGRIVGMNSF
GESAPADQLFKLFGFTVDNVVAKAKEIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 77
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 68