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Name : leuS (APL_0872) Accession : YP_001053573.1 Strain : Actinobacillus pleuropneumoniae L20 Genome accession: NC_009053 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 1012144 - 1014729 bp Length : 2586 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGCAACAACAATATAACCCAAGTGCGATTGAACCTAAGGTTCAGCAATTCTGGGCAGAAAATAAAGTTTTTAAAGCGGT TAAAGATGTAACAAAAGAGAAATACTATTGCCTTTCAATGTTGCCGTATCCGTCCGGTAAATTACATATGGGTCACGTAC GTAACTATACAATCGGTGATGTGGTTTCTCGTTATCAACGTATGATTGGTAAAAACGTGTTACAGCCGATGGGTTGGGAT GCTTTCGGTTTACCGGCGGAAGGTGCGGCGGTAAAAAATAACACGGCGCCAGCAAAATGGACGTACGAAAATATCGAATA TATGAAAGGTCAGCTCAAAATGTTGGGCTTTTCTTATGACTGGGATCGAGAAGTCACCACTTGCCGTCCGGAATACTACA AATGGGAACAATGGTTCTTCACCGAACTTTACAAAAAAGGGTTAGTGTATAAAAAAACCTCAACGGTAAACTGGTGTCCG AACGATGCGACTGTGCTTGCAAACGAACAGGTGCACGAAGGTTGTTGTTGGCGTTGTGATACGCCGGTAGAACAACGTGA GATTCCTCAATGGTTTATCAAAATTACCGACTATGCCGAAGAGTTATTAACTCACTTAGATAATCTTCCGCAATGGCCTG ATCAAGTAAAAACCATGCAACGTAACTGGATCGGTCGTTCTGAAGGGGTTGAAATCACCTTCAAAATCGCCGGTTCAAAT GCGGAATTACCGGTTTACACCACTCGTCCGGATACCTTCTTCGGTGTGAGCTATGTTGCGATTGCCGCTGCTCATCCATT AGCGGAAATGGCGGCAGAAAACAATCCTGCACTTGCAGAATTTATTCGTGAGGCGAAAAACACCAAAGTTGCAGAAGCAG AATTAGCAACAATGGAGAAAAAAGGGATGGCAACCGGCTTGTTCGCTATCCACCCGCTAACAGGTAAAGAAGTACCGGTT TGGGTTGCTAACTTCGTATTAATGCACTACGGTACAGGAGCAGTAATGGCTGTGCCGGCACACGATGAACGTGACTTTGA ATTTGCTCAAAAATACGGTTTGCAAATTAATCAAGTAATTCAACCGCTTGACGGTTCCGAATGGGATTTCTCAAAAGCCG CTTATACCGAGCACGGTAAATTGATTAATTCGGCTGAATTTGACGATTTAAATTTTGAGCAAGCATTCAATGCGATTGCC GATAAATTAGAATCGATGAAAGTGGGTAAACGCCAAGTAAACTTCCGTCTGCGTGACTGGGGGGTATCTCGTCAGCGTTA CTGGGGTGCGCCAATCCCAATGATGACGACCGAAGACGGCGAAGTAGTAACAGTGCCGATGCAAGATTTACCGGTCATTC TACCTGAAGATGTGGTAATGAACGGCGTACAAAGCCCGATCAAAGCTGATCCTGAGTGGGCGAAAACCACTTACAACGGC AAACCTGCGTTAAAAGAAACCGATACGTTCGATACCTTTATGGAATCGTCTTGGTACTATGCACGCTATACTTGCCCGCA ATATCACGAAGGTATGTTAGATTCTGACGAGGCAAACTACTGGTTACCAGTCGATCAATATATCGGCGGTATCGAACACG CAACCATGCACTTGCTCTATTTCCGCTTCTTCCACAAATTGTTACGTGATGCGGGTATTTTGAACTCTGACGAACCGGCA ACTAAACTTTTATGTCAAGGTATGGTGCTTGCTGATGCGTTCTATTACACCAGCCCGACTAACGAGCGTATTTGGGTTAG CCCGACACAAGTCACGCTTGAGCGTGATGAGAAAGGTCGCATCATCAAAGCGACTGATCCGGAAGGCCGTGAATTAGTTC ACAGCGGTATGACCAAAATGTCGAAATCGAAAAATAACGGCATCGACCCGCAAGAAATGGTGGAAAAATACGGTGCGGAC ACAGTACGTTTATTTATGATGTTCGCTTCACCGGCAGAAATGACGCTTGAATGGCAAGAATCCGGTGTGGAAGGTGCAAA ACGCTTCTTAGGTCGTGTGTGGAATTTAGTGTATGAATATAGCCAAAATCCTGCGACAGCAGCATTAGATGTAGCCGCAT TAAGCAAAGCACAAAAAGAACTTCGCCGTGACGTACACAAAACCATTGCGAAAGTGTCTGACGATATCGGTCGCCGTCAA ACATTCAATACTGCAATCGCGGCGATTATGGAATTAATGAACAAGCTGACGAAAGCACCACTTGAAAACGAACAAGACAA AGCGGTAATGGCGGAAGCATTAAGTGCGGTTGTACGTATGCTTTACCCAATTACGCCACATATCTGTTTCGAATTATGGC AAGCGCTAGGTAATAACGATACGATTGACTTTGCGCCATGGGTAGTTGCAGATGAGTCAGCAATGGTTGAAGACGAAAAA TTAGTTGTGGTACAAGTAAACGGTAAAGTTCGTGGTAAAGTTACCGTTTCGGCAACAGCAACCGAAGATGAAGTCAAAGC AATTGCGAAAGCGGATGCAAACGTAGCGAAATTCTTAGAAGGCGTAGAAATCGTGAAAGAAATCTATGTACCGTATAAGA TGTTAAGTTTTGCGGTAAAAGCCTAA Protein sequence : MQQQYNPSAIEPKVQQFWAENKVFKAVKDVTKEKYYCLSMLPYPSGKLHMGHVRNYTIGDVVSRYQRMIGKNVLQPMGWD AFGLPAEGAAVKNNTAPAKWTYENIEYMKGQLKMLGFSYDWDREVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCP NDATVLANEQVHEGCCWRCDTPVEQREIPQWFIKITDYAEELLTHLDNLPQWPDQVKTMQRNWIGRSEGVEITFKIAGSN AELPVYTTRPDTFFGVSYVAIAAAHPLAEMAAENNPALAEFIREAKNTKVAEAELATMEKKGMATGLFAIHPLTGKEVPV WVANFVLMHYGTGAVMAVPAHDERDFEFAQKYGLQINQVIQPLDGSEWDFSKAAYTEHGKLINSAEFDDLNFEQAFNAIA DKLESMKVGKRQVNFRLRDWGVSRQRYWGAPIPMMTTEDGEVVTVPMQDLPVILPEDVVMNGVQSPIKADPEWAKTTYNG KPALKETDTFDTFMESSWYYARYTCPQYHEGMLDSDEANYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGILNSDEPA TKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLERDEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGAD TVRLFMMFASPAEMTLEWQESGVEGAKRFLGRVWNLVYEYSQNPATAALDVAALSKAQKELRRDVHKTIAKVSDDIGRRQ TFNTAIAAIMELMNKLTKAPLENEQDKAVMAEALSAVVRMLYPITPHICFELWQALGNNDTIDFAPWVVADESAMVEDEK LVVVQVNGKVRGKVTVSATATEDEVKAIAKADANVAKFLEGVEIVKEIYVPYKMLSFAVKA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 1e-155 | 42 |
