Gene Information

Name : serS (APL_0868)
Accession : YP_001053569.1
Strain : Actinobacillus pleuropneumoniae L20
Genome accession: NC_009053
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1007146 - 1008453 bp
Length : 1308 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATCGACCAAAATCTTCTTCGTACTAATTTAGACGATGTTGCAAATGCACTTAAAGTTAAACGTGGTTTTACCCTTGA
TGTAGAGAGTGTAAAAGCATTGGAAGAAAAACGTAAAGCACTTCAAGTTAAAACAGAAACCTTACAAGCGGAACGTAACG
CCCGTTCGAAAAATATCGGTGCGGCAAAAGCTCGCGGCGAAGATATTTCTGCGTTATTAGCGGAAGTAGATAATATGGGT
AACGAATTAAACGAAGCGAAAGTCGCTTTAGACCAAGTTCAAGCGGAAATTCGTGAATTACTCTTATCTGTGCCGAACTT
ACCGGCTGACGAAGTACCGTTAGGTAAAGACGACACGGAAAACTTAGAAGTGTCACGTTGGGGCGAGCCTCGTCAATTTG
ACTTTGAAGTAAAAGATCACGTGGCATTAGGTGAGGCGTTAAACGGTTTAGATTTTGCTGCCGGCGTAAAATTAACCGCT
AGCCGTTTTGTGGTCATGAAAGGTAAACTTGCTCGTTTACACCGTGCTTTATCGCAATTTATGTTAGATCTTCATACCGA
ACAACACGGTTATGTGGAAACAAATGTACCGTTCTTAGTGAACCACGACACGCTGTTCGGTACCGGTCAATTACCGAAAT
TCGGTGAAGATTTATTCCATACTCAACCATTAACCGGTCAAGATCCTAACGAAACGCAACGTCCGTTCAGCTTAATTCCA
ACGGCGGAAGTACCGGTAACAAACTTAGTGCGTGACGAAATTATTGATGAAAACAGCTTACCGCTACGCTATACGGCACA
TACGCCGTGTTTCCGTTCTGAAGCAGGTTCTTACGGTCGTGACACACGCGGTTTAATTCGTATGCACCAATTCGAAAAAG
TGGAAATGGTACAGATCGTTGCACCGGAAAAATCAATGGAAGCGTTAGAAGAATTAACCGGTCACGCTGAAAAAGTATTA
CAACTTTTAGGCTTACCATACCGTAAAGTTTTACTTTGTACCGGCGATATGGGCTTCGGTTCAGCAAAAACTTATGACTT
AGAAGTTTGGTTACCGGCACAAAATACTTACCGTGAGATTTCTTCTTGCTCAAATATGTGGGATTTCCAAGCTCGCCGTA
TGTCTGCACGTTGCAAAGCGAAAGGCGACAAGAAAACTCGCTTAGTCCACACCTTAAACGGCTCAGGTTTAGCGGTGGGT
CGTACGTTAGTTGCGGTACTTGAAAACTATCAAAACGCTGACGGTTCAATCACTGTTCCGGAAGTATTACGTCCATATAT
GGGCGGTGTGGAAGTGATTACCGCTTAA

Protein sequence :
MIDQNLLRTNLDDVANALKVKRGFTLDVESVKALEEKRKALQVKTETLQAERNARSKNIGAAKARGEDISALLAEVDNMG
NELNEAKVALDQVQAEIRELLLSVPNLPADEVPLGKDDTENLEVSRWGEPRQFDFEVKDHVALGEALNGLDFAAGVKLTA
SRFVVMKGKLARLHRALSQFMLDLHTEQHGYVETNVPFLVNHDTLFGTGQLPKFGEDLFHTQPLTGQDPNETQRPFSLIP
TAEVPVTNLVRDEIIDENSLPLRYTAHTPCFRSEAGSYGRDTRGLIRMHQFEKVEMVQIVAPEKSMEALEELTGHAEKVL
QLLGLPYRKVLLCTGDMGFGSAKTYDLEVWLPAQNTYREISSCSNMWDFQARRMSARCKAKGDKKTRLVHTLNGSGLAVG
RTLVAVLENYQNADGSITVPEVLRPYMGGVEVITA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 6e-108 54