Gene Information

Name : smpB (APL_0867)
Accession : YP_001053568.1
Strain : Actinobacillus pleuropneumoniae L20
Genome accession: NC_009053
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1006549 - 1007028 bp
Length : 480 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCAAAAAAACCAAAAGTAGCTTCGAATACGATTGCGTTGAATAAACGTGCTCGTCATGAATATTTTATCGAAGAAGA
AATTGAAGCCGGCTTAGAATTACAAGGCTGGGAAGTAAAATCGTTGCGTGCCGGTAAAGCGAATATCGGCGACAGTTACG
TGACATTTCGTAACGGCGAAGCGTTTCTATTCGGTGCAACCATCACACCATTAAATATGGCTTCTACTCACATTGTTTGT
GATCCGACTCGCACCCGTAAATTATTATTGAATAAACGTGAATTAGATTCGCTATTCGGTAAAGTAAATCGAGACGGTAT
GACGGTTGTGGCATTATCGCTCTACTGGAAAAACGCGTGGGCGAAAGTGAAAGTCGGCGTAGCAAAAGGTAAAAAACTAC
ACGATAAACGTGAGGACATTAAAGACCGTGAATGGCAAGTAGCGAAACAGCGTATTATGAAAAACGCAAATCGTGGCTAA

Protein sequence :
MAKKPKVASNTIALNKRARHEYFIEEEIEAGLELQGWEVKSLRAGKANIGDSYVTFRNGEAFLFGATITPLNMASTHIVC
DPTRTRKLLLNKRELDSLFGKVNRDGMTVVALSLYWKNAWAKVKVGVAKGKKLHDKREDIKDREWQVAKQRIMKNANRG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 8e-44 69
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 3e-14 43