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Name : topB2 (APL_0744) Accession : YP_001053449.1 Strain : Actinobacillus pleuropneumoniae L20 Genome accession: NC_009053 Putative virulence/resistance : Unknown Product : DNA topoisomerase III Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0550 EC number : 5.99.1.2 Position : 849112 - 851049 bp Length : 1938 bp Strand : - Note : decatenates replicating daughter chromosomes DNA sequence : ATGATATCAGAGAAAAGAATTTTGAGAGTATTTTTAGCGGAAAAACCGAGTTTGGCAAGAGCAATCGCAGACGTATTGCC GAAGCCGCATACCCGTGGTGACGGCTATATTCAATGTGGTGAAAATGATACGGTAACTTGGTGTATCGGTCATTTATTGG AACAAGCGGAACCTGATATTTACGACGAACGTTTTAAAATGTGGCGAATGGAGCATTTGCCGATTGTCCCGCAGCAATGG AAATTAGTGCCGAAAAAAGAAACGTTGAAGCAGTTAAAAGCGGTCGAAAAATTGGTAAAAAAAGCGGACGTATTGGTAAA CGCCGGCGACCCGGACCGAGAAGGGCAGCTATTAGTTGATGAGGTCTTTAGCTATCTGAACGTACCGCCGGAAAAACGTA ATCGGATTCAACGTTGTTTGGTGAGCGATCTCAACCCGAGTGCGGTAAAAAAAGCGATTGATAAATTGCAAAATAATCGT GATTTTATACCGCTTGCCACCTCTGCCTTAGCACGTGCAAGAGCCGATTGGCTATACGGCATTAATATGACGCGAGCTTA TACCTTACAAGGACGTTGGGCGGGCTATCAAGGGGTATTGTCGGTGGGGCGTGTTCAAACCCCCGTGTTAGGTTTAATTG TGCGCCGCGATCTGGAAATAGAAAACTTTGTGCCGAAAGACTATTTTGAAGTATTGGCGCATATCGTTGTGCCGGAAACT CAAGAACGTTTTACTGCCCAATGGCAACCGAGTAAGGCGTGCGAAGATTATCAAGATGAAGACGGTCGAGTATTATCTAA AAGTTTGGCGGAAAATGTCGTTAAACGCATTACCGACCAAGCAGCATTAGTAACGGATTATCAAGATAAAATTGAAACGG AAACCGCACCGCTGCCTTATTCATTATCGGTATTACAAATTGATGCGGCACGCCGTTACGGCCTATCGGCACAAGCTGTG TTGGATATTTGTCAGAAACTGTATGAAACGCATAAGCTGATTACCTATCCCCGTTCGGATAACCGTTATCTACCGAATGA GCATTACGCTGATCGTTTTAAAGTGATGGCGGCGATTGCACATCATCTGGATGAGTATAAAGAAAAACCGGAGGCGGTTA ATCCGGAAATTCGTAATCGTTGTTGGAATGATAAAAAGGTAGAAGCGCACCATGCTATTATTCCGACCGTACGCCAAGGC TCGGTAAAACTAACTGAAAACGAAAAGCGTATTTATCAACTGATTGCCCGTCAATACTTAATGCAATTTTGTCCGGATGC GGAATATCGCAAAGGTAAAATTGTATTGGAGATTGCCGGAGGAACTTTTAACGCGCAGGCTCGGAACTTAATTGTTGCCG GTTGGAAAGCATTATTAGGCAAAGAAGACAGTGACGAAGTGTTAGAGCCGTTATTACCGGTTGTGAAAAAAGGGCAGCAA TTACATTGTGAAAAAGGTGAGATTGTCAGTAAGAAAACCCAGCCGCCTCGTCATTTTACCGACGCAAGTTTATTATCGGC AATGACCGGTATCGCTCGTTTCGTACAAGATAAACAACTTAAAAAAGTCTTACGTGAAACGGACGGCTTAGGTACTGAAG CAACACGTGCCGGTATTATCGAATTGCTGTTTAAACGCGGATTTTTAATCAAAAAAGGACGAAATATCCACAGTACGGAA GCCGGGCGAATTCTAATTAGTGCCTTACCGGACGAAGCGACTCAGCCGGATATGACTGCGCATTGGGAAATGCAACTTAC CGACATTAGTAAGAAGCAAGCGAGTTATCAGCAGTTTATGCAAGTACTTACGAGTAAATTACCTGAGTTATTACATACGG AACGACAAAAATTGCAAAATTTAAGTCGAATTCAACCGCCCGCCTCTTATCGTAAGCGGTCAAATTTTAAGAAAAATTTA CAAACTGCTGAAAAATAA Protein sequence : MISEKRILRVFLAEKPSLARAIADVLPKPHTRGDGYIQCGENDTVTWCIGHLLEQAEPDIYDERFKMWRMEHLPIVPQQW KLVPKKETLKQLKAVEKLVKKADVLVNAGDPDREGQLLVDEVFSYLNVPPEKRNRIQRCLVSDLNPSAVKKAIDKLQNNR DFIPLATSALARARADWLYGINMTRAYTLQGRWAGYQGVLSVGRVQTPVLGLIVRRDLEIENFVPKDYFEVLAHIVVPET QERFTAQWQPSKACEDYQDEDGRVLSKSLAENVVKRITDQAALVTDYQDKIETETAPLPYSLSVLQIDAARRYGLSAQAV LDICQKLYETHKLITYPRSDNRYLPNEHYADRFKVMAAIAHHLDEYKEKPEAVNPEIRNRCWNDKKVEAHHAIIPTVRQG SVKLTENEKRIYQLIARQYLMQFCPDAEYRKGKIVLEIAGGTFNAQARNLIVAGWKALLGKEDSDEVLEPLLPVVKKGQQ LHCEKGEIVSKKTQPPRHFTDASLLSAMTGIARFVQDKQLKKVLRETDGLGTEATRAGIIELLFKRGFLIKKGRNIHSTE AGRILISALPDEATQPDMTAHWEMQLTDISKKQASYQQFMQVLTSKLPELLHTERQKLQNLSRIQPPASYRKRSNFKKNL QTAEK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| topB | NP_458624.1 | topoisomerase B | Not tested | SPI-7 | Protein | 2e-108 | 41 |
| topB | NP_807836.1 | DNA topoisomerase III | Not tested | SPI-7 | Protein | 2e-108 | 41 |
| topB | AAF14809.1 | topoisomerase B | Not tested | SPI-7 | Protein | 1e-108 | 41 |
