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Name : metB (APL_0683) Accession : YP_001053388.1 Strain : Actinobacillus pleuropneumoniae L20 Genome accession: NC_009053 Putative virulence/resistance : Resistance Product : cystathionine gamma-synthase Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG0626 EC number : 2.5.1.48 Position : 780978 - 782114 bp Length : 1137 bp Strand : - Note : catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity DNA sequence : ATGACCAAATACAGTAACATTGAAACCACATTAGTACAGTTAGGCAACCGCACCGACCCTAGAACGGGAGCGGTAGCCAC ACCGATTGTTTTATCGACCGCTTATGGTCGTGGCGGTTTGGGCGAATCGACCGGTTGGGATTATATTCGTACCAAAAACC CGACCCGTGCCGTGTTAGAGCAAGGTATTGCTGATTTAGAGGGGGGAGATGCCGGTTTTGCAATGGCATCGGGTATGGCG GCAATTCAGTTAGTGATGTCATTGTTTAAAGCGCCTGATGAGTGGATTATTTCAAGTGATGTATATGGCGGCTCTTACCG TTTATTCGATTTCAGTCATAAACACCACAATACAGTAAAACCGGTTTATGTAAATACCGCAGATTTGGCGGCGATTGAAG CGGCAATTACCCCAAACACTAAAGCGATTTTTGTCGAAACACCGTCAAACCCATTAATGGAAGAGTGTGATGTTGATGCA ATTTCTAAAATTGCGAAAAAACATAACTTAATGTTAATTGTGGATAATACCTTCTTAACGCCGATTTTATTCCGTCCGAT TGAACACGGTGCGGATATCGTGATTCACAGTGCAACGAAATACCTTTCCGGTCATAATGATGTGTTAGCCGGTTTAATCG TTGCGAAAGATTCGGAAGCAACCAAAAACGAAGCGGGTCAAAAGCTTTCGGAACGTTTATTCTACTTCCAAAACTGTGCT GGTGCGGTGCTTTCGCCGTTTGATTCTTACCTTGCGGTGCGTGGCTTAAAAACCCTTGCGTTACGTATGGAACGCCACCA ATCGAATGCTACGGAATTAGCGAGATTCTTAAGCGAGCAACCGGAGATTGAGTGCGTACTTTATTCAGGTAAGAGCGGTA TGCTTTCATTCCGTTTACAAAAAGAAGAGTGGGTACCGAAATTCTTAAAAGCGATTAAGTTGATTACCTTTGCGGAAAGT TTAGGCGGTACGGAAAGTTTTATCACTTATCCGTCCACTCAAACACATATGGATATTCCGGAAGCGGAGCGTATTGCACG TGGTATCACCAATAACTTACTGCGTTTCTCAGTTGGCTTGGAACATGTTGAAGATTTAAAAGTGGATTTACGCCAAGCGT TCGGACAACTAAAATAA Protein sequence : MTKYSNIETTLVQLGNRTDPRTGAVATPIVLSTAYGRGGLGESTGWDYIRTKNPTRAVLEQGIADLEGGDAGFAMASGMA AIQLVMSLFKAPDEWIISSDVYGGSYRLFDFSHKHHNTVKPVYVNTADLAAIEAAITPNTKAIFVETPSNPLMEECDVDA ISKIAKKHNLMLIVDNTFLTPILFRPIEHGADIVIHSATKYLSGHNDVLAGLIVAKDSEATKNEAGQKLSERLFYFQNCA GAVLSPFDSYLAVRGLKTLALRMERHQSNATELARFLSEQPEIECVLYSGKSGMLSFRLQKEEWVPKFLKAIKLITFAES LGGTESFITYPSTQTHMDIPEAERIARGITNNLLRFSVGLEHVEDLKVDLRQAFGQLK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SAR0460 | YP_039909.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 1e-62 | 43 |
| SAS0418 | YP_042545.1 | Cys/Met metabolism PLP-dependent enzyme | Not tested | vSa¥á | Protein | 2e-63 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| metB | YP_001053388.1 | cystathionine gamma-synthase | BAC0207 | Protein | 2e-50 | 42 |
