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Name : hsdR3 (APL_0636) Accession : YP_001053343.1 Strain : Actinobacillus pleuropneumoniae L20 Genome accession: NC_009053 Putative virulence/resistance : Unknown Product : type I site-specific restriction-modification system, restriction subunit Function : - COG functional category : V : Defense mechanisms COG ID : COG0610 EC number : 3.1.21.3 Position : 724743 - 727883 bp Length : 3141 bp Strand : + Note : - DNA sequence : ATGCACATCAACGAAAACACAATAGAGCAAGCCTGTATTCAGGCATTACAAGGCTTGGGGTGGGCTTATACCTTTGGTTC GGAGATTGAGCGGGAGCGAGCTGAAGAGGTGGTGCTGAAATCGGTGTTGGCGAATGCGATAACAAGGCTAAATCCGCAGT TACCGAGTAATGTGGTCAATGACGTGGTGGCGTTGGTGTGTAAGGGCGATATTACCGATTTAACTGAGCGTAATCAGCAA TTTTACCGCTTGTTGCGTGAAGGCGTGCGGGTGGAGTATCGTGAAAATGATGAGCAGAAAATCGACATTGTTCGTTTGAT TGATTTTCAAAATGTTCACAACAACCAGTTTGATGTGGTAAATAAATTCACGATTAAGGGGTTGAAAGGCAACCGCCGCC CTGATGTGATTTGCTTTGTGAATGGTTTGCCGTTGGTGGTGTTTGAGTTGAAAAATCCGCTTACAGAATCAGCCGATTTG CAACAGGCATTTCAACAGTTCCAAACCTATAAAGCAGAAATTAGCGATCTCTTTGTTTTCAATCAAGCCCTTGTGATTAG TGACGGTACGCACGCTCGCATTGGTTCTTTAACCGCTAATTTTGACCGCTTTACCCCGTGGCGAGTGGTGGACGAAAAAG CCAAACAGCGAGTGTCGTTTGAAAATGAGTTGGCGGGCTTGGTGCAAGGGCTGATGTCGCCTGAAAATTTGCTCAATTAT GTGCAGAATTTCGTGCTATTTGAGCGTTCGGAAAGCGGTCAGTTAATCAAAAAAATTGCCGCTTATCATCAATTCTATGG AGTGAATGAGGCGGTAGAGTCCACGTTGCTTGCAGCAAGCGAGCAGGGCGACCGCAAAATTGGCGTGATGTGGCACACGC AGGGTTCGGGCAAGTCGATTTCAATGCTCTTTTATGCGGCAAAATTACAAGCGGAGCCGAGTTTGCGTAACCCAACCATT GTGGTGGTAACCGACCGCAATGATTTGGACGGTCAGCTTTTTGCTACCTTTTCGGCAGGTAAAGATTTGATTCGCCAAAC GCCGATTCAAGCAGACGGTCGGGAAGCCTTGCGCGTGGAACTTGCCAAGCGTGAAACGGGTGGCATTATTTTTACCACCA TTCAAAAATTCGGCTTGCAAGAGGGCGAAAATGAGCACCCTATTTTAAATGATCGCCAAAACATCATCGTAATTAGCGAT GAGGCTCACCGCTCCCAATATGGCTTTACCCAGCATTTGTCAATGGGATCGCAATCCGCAGCCTACCGAGTGGGCTATGC CAAACATTTGCGAAATGCATTGCCGAATGCTTCGTTCATCGGTTTTACTGGCACGCCAATTTCCCTTGAAGATAAAGATA CTCAAGCGGTGTTTGGGCGTTATGTGTCGATTTACGACATTCAAGATGCGGTGGAAGACGGAGCGACCGTGCCGATTGTG TATGAGGCTCGCCAAATTCCGATTAATGAGAGCCAAGATTTCCAAACTGCGGTGCAAGAAGCGGACGATTTATTTTCGGA CGATGAACAGAGTTATAGTTTCCGTTTGCGTGAAAAGTTAATGGGAGCAGACACAAGGCTCACAAAATTGGCGGAAGATT TGGTAAAACATTTTGAAAATCGTACCGCTTTAATGGACGGCAAGGCGATGATTGTGGCAATGAGCCGTCAAATTTGTGTG GCGTTGTATGACAAGATTATCGCCCTTCGCCCTGAATGGCATAGCGACAATCTCAACGAAGGGGCGATTAAAATTGTGAT GACAGGCTCGGCAAGTGATCCTGACCATTTTCAACCGCACATTTATGGCAATCAAGAGAAGAAAACTCTCGAAAAACGTT TTAAAGATCCTAACGATCCGCTCAAACTTGTGATTGTGCGAGATATGTGGCTGACAGGCTTTGATGCACCTTGCTGTAAC ACAATGTATATCGACAAGCCAATGAAAGGGCATAATCTAATGCAAGCAATCGCCCGAGTGAATCGTGTTTTCCGCAACAA AAGCCGTGAAAATGGTGGGTTAATTGTCGATTATGTGGGCTTGGTGGACGAACTTAAATCGGCAACGGCTGAATATACCA ATGCCAACGGTAAGGGCGAAATGGTGAACGATATTGAGAAAATTAAACTCAAGTTTTTAGAGTGTTTGGATATTGTGCGA GGGATGTTTGCCAGCCCTGTAAGCGGTCAAATTTTTCCATTATTTGACGTATTAAAAATTCACGATGAAATGGCGTTGTT TGAGCAAATTCTAACGGCAGCAAACCATATTTTAAGCCTAGATCAGCAAAATCCTGTTGATGACAAAGCAAAAGATAAAA CGCCTCGTAAAAATCGATTCTTGCAAGCGATGAGATTGGCGAAAAAGGGCTACGGTTTGTGTGGTTCATTGCCTGAAGTG CAAGCCTATCAGCGAGAATTGGCGTTTATTGATGCGGTGCGAGCAATGCTTGCAAAACGTGAGCCAAATTCGACCGCTAA TCCAGCCGACCGACAACTTAAATTAGTGGCGTTGTTGAATCAAGCTGTGAAAGCCGATGGGGCAGTGGATTTATTTGCGT TGCTTAATCGAGATCAGCCAAACATCGAGATTTTGTCTGAACAATTTTTGGAGCAAGTGAAAAACAGTCGCCACAAAGCC TTGTGGTTAGAGGCAATTCAGCGTTATTTGCAAGCGGAATTTAAAGAAAAAGGGGTGAGTAATCTTTCCGTACAAAAAGA TTTTGAAACTCGATTAAAAGAGGCGATGAATAAATATCGCAACCAAAATTTGACCTTACTTGAAATTTTGGACGAATTAT TGGCAATGGGCAAAGAGTTTGCCGAACGTTTGGCTCGTGGCGAGAAGTTAGGGCTAACGCCTGCAGAAATCGCCTTTTAT GACGCATTGGCTCAAAACGAAAGTGCGGTGCGAGAATTGGGTGATGACGTCTTGAAAAATTTGGCAATGACAATTACTGA GAAAATCCGCCAATCTGCCACGATTGACTGGCAATTTAAAGATTCCGTGCGAGCCAAAATGCGGATTGAAATCCGCCGAG CGTTAAGATTATTCAAATATCCGCCTGATAAACAAGCAGAAGCAGTCGAGTTTGTATTAAAACAGGCGGAAGTGATTGCA GATGAATTGAGTTCTCCCTAA Protein sequence : MHINENTIEQACIQALQGLGWAYTFGSEIERERAEEVVLKSVLANAITRLNPQLPSNVVNDVVALVCKGDITDLTERNQQ FYRLLREGVRVEYRENDEQKIDIVRLIDFQNVHNNQFDVVNKFTIKGLKGNRRPDVICFVNGLPLVVFELKNPLTESADL QQAFQQFQTYKAEISDLFVFNQALVISDGTHARIGSLTANFDRFTPWRVVDEKAKQRVSFENELAGLVQGLMSPENLLNY VQNFVLFERSESGQLIKKIAAYHQFYGVNEAVESTLLAASEQGDRKIGVMWHTQGSGKSISMLFYAAKLQAEPSLRNPTI VVVTDRNDLDGQLFATFSAGKDLIRQTPIQADGREALRVELAKRETGGIIFTTIQKFGLQEGENEHPILNDRQNIIVISD EAHRSQYGFTQHLSMGSQSAAYRVGYAKHLRNALPNASFIGFTGTPISLEDKDTQAVFGRYVSIYDIQDAVEDGATVPIV YEARQIPINESQDFQTAVQEADDLFSDDEQSYSFRLREKLMGADTRLTKLAEDLVKHFENRTALMDGKAMIVAMSRQICV ALYDKIIALRPEWHSDNLNEGAIKIVMTGSASDPDHFQPHIYGNQEKKTLEKRFKDPNDPLKLVIVRDMWLTGFDAPCCN TMYIDKPMKGHNLMQAIARVNRVFRNKSRENGGLIVDYVGLVDELKSATAEYTNANGKGEMVNDIEKIKLKFLECLDIVR GMFASPVSGQIFPLFDVLKIHDEMALFEQILTAANHILSLDQQNPVDDKAKDKTPRKNRFLQAMRLAKKGYGLCGSLPEV QAYQRELAFIDAVRAMLAKREPNSTANPADRQLKLVALLNQAVKADGAVDLFALLNRDQPNIEILSEQFLEQVKNSRHKA LWLEAIQRYLQAEFKEKGVSNLSVQKDFETRLKEAMNKYRNQNLTLLEILDELLAMGKEFAERLARGEKLGLTPAEIAFY DALAQNESAVRELGDDVLKNLAMTITEKIRQSATIDWQFKDSVRAKMRIEIRRALRLFKYPPDKQAEAVEFVLKQAEVIA DELSSP |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| api52 | CAF28526.1 | hsdr-like Type I restriction enzyme | Not tested | YAPI | Protein | 0.0 | 49 |
| hsdR | BAH57699.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-VII SCCmec | Protein | 0.0 | 42 |
| hsdR | BAD24840.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-V SCCmec | Protein | 0.0 | 42 |
| hsdR | YP_251977.1 | type I restriction-modification system restriction subunit | Not tested | SCCmec | Protein | 0.0 | 41 |
