Gene Information

Name : hsdM3 (APL_0633)
Accession : YP_001053340.1
Strain : Actinobacillus pleuropneumoniae L20
Genome accession: NC_009053
Putative virulence/resistance : Unknown
Product : type I modification enzyme
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 2.1.1.72
Position : 721030 - 722595 bp
Length : 1566 bp
Strand : +
Note : -

DNA sequence :
TTGGAAAAAGCTGCCGACAAACTCCGCCAGCAATTAGACGCAGCCAACTACAAGCATATTGTGCTTGGTTTAATTTTCCT
CAAATACGTTTCTGATAGTTTCACCGCACAGCGTGAACGCCTTTCTGCACAATTCCGAGATCCAAATTCTGACTACTATT
TGTCAGATATAACCACCGAAGAAATCGAATCTGAACTCGAAGAACGGGATTACTACACCCAAGATAACGTGTTTTGGGTG
CCTCAAATCGCCCGTTGGAACGAAATCAAAGCCGTAGTACGAGCTAATTTAGGTGACACCATTTTTGAGAACAAAACCTT
TAAAGGCGTGGCAAATTTGATTGATGAAGCCTTTGACGCTATTGAAAAAGACAACCCAAAATTGAAAGGTGTGATTCAAC
GTATTTCGAGCTACAACGTGGACGAAAGTATTTTAATCGGCTTAGTGGAATTGTTTTCTGACACCAACTTCACTCACCCA
ACGCTTAACGGCAAGCCTGTTTCTTTGGCAGCAAAAGATATTTTAGGACATGTTTACGAGTATTTTCTCGGACAATTTGC
TCTCGCAGAAGGCAAGAAAGGCGGGCAGTATTTCACGCCAAAATCTATTGTTACCCTGATCATCGAAATGCTCGAACCCT
ACGAAGGGCGAATTTACGACCCTGCAATGGGATCAGGCGGTTTCTTCGTGCAAACCGAACGTTTTATCCGTGAACATCAG
GGCAACCCAAACCGTGTGTCGATTTATGGGCAAGAATTTAACCCAACCACTTGGAAACTGGCTGCAATGAATATGGCAAT
TCGTGGCTTGTCGTTTGATTTTGGCAAGGGCAATGCCGACACGTTTAGCAATCCACAACATCTCGATAAACGAATGGATT
TTGTGATGGCGAACCCACCGTTCAATATGAACGAATGGTGGAATCAAAGCCTTGCCAACGATCCACGCTGGAAATTTGGC
ACGCCACCGTCTAGCAACGCCAACTTTGCGTGGTTGCAACATATGATTTACCACCTTTCCGAAAAAGGCAAAATGGCGTT
ATTGCTTGCCAACGGCTCAATGTCGAGCAACACCAACAACGAGGGCGAAATCCGCCGTAACATCGTACGAGCCGATTTGG
TGGAAGCGATGATTGCCTTGCCAAGCCAATTATTTACCAATACACAAATCCCAGCTTGCATTTGGGTGCTGAACAAAGCC
AAACCACGCAAGGGCGAAGTGCTGTTTATTGATGCTCGCCAACTTGGTTATATGAAAACCCGTGTAATGCGTGATTTCAC
GCCAAAAGACATTGCAAGCGTAGCAGAAACCTACCACCAATGGCAAAAAGGAGAAGGTTATCAAGACGTGCCAGCATTCT
GCAAATCCGCCACCCTTGCCGAGATCGAAAGCCACGATTTTGTGCTAACCCCGGGGCGATACGTTGGAGCGGCTGAGGTG
GAAGATGACGGCATTCCATTTGCAGAAAAAATGCAAAATCTGACCGCACTTTTAAACGAACAATTCAAACAAGGGGCGGA
ATTAGAAGCAAAAATCCGAGCGAATTTGGCAACGCTCGGGTTTTAA

Protein sequence :
MEKAADKLRQQLDAANYKHIVLGLIFLKYVSDSFTAQRERLSAQFRDPNSDYYLSDITTEEIESELEERDYYTQDNVFWV
PQIARWNEIKAVVRANLGDTIFENKTFKGVANLIDEAFDAIEKDNPKLKGVIQRISSYNVDESILIGLVELFSDTNFTHP
TLNGKPVSLAAKDILGHVYEYFLGQFALAEGKKGGQYFTPKSIVTLIIEMLEPYEGRIYDPAMGSGGFFVQTERFIREHQ
GNPNRVSIYGQEFNPTTWKLAAMNMAIRGLSFDFGKGNADTFSNPQHLDKRMDFVMANPPFNMNEWWNQSLANDPRWKFG
TPPSSNANFAWLQHMIYHLSEKGKMALLLANGSMSSNTNNEGEIRRNIVRADLVEAMIALPSQLFTNTQIPACIWVLNKA
KPRKGEVLFIDARQLGYMKTRVMRDFTPKDIASVAETYHQWQKGEGYQDVPAFCKSATLAEIESHDFVLTPGRYVGAAEV
EDDGIPFAEKMQNLTALLNEQFKQGAELEAKIRANLATLGF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
api49 CAF28523.1 putative HsdM-like N-methyl transferase Not tested YAPI Protein 5e-157 61
hsdM YP_251979.1 type I restriction-modification system DNA methylase Not tested SCCmec Protein 5e-113 46
hsdM BAH57701.1 type I restriction-modification system DNA methylase Not tested Type-VII SCCmec Protein 1e-112 46
hsdM BAD24842.1 HsdM protein Not tested Type-V SCCmec Protein 3e-111 45