Gene Information

Name : aldA (APL_2011)
Accession : YP_001054690.1
Strain : Actinobacillus pleuropneumoniae L20
Genome accession: NC_009053
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase aldA
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 2236287 - 2237768 bp
Length : 1482 bp
Strand : -
Note : -

DNA sequence :
ATGAAAGATCTTAACGTTTTCGATAAAAATTACGGCTTATTAATCAATGGCAAATGGACTCAAGGCAGCGGTAACGATTT
ACTTCCTTCTTACAATCCGGCGAACGGTGAAGTATTAGCGCATTTTGTCGATGCAACCGATGCGGATGTGGATGCGGCGG
TGAAAGCGGCACAAGAAGCATTCAAATCTTGGCGTAAAACGACAGTGGCGGAACGTGCGGCGATTTTAAATAAAATTGCC
GATGTGATTGATGAAAATAGTGAATTATTTGCATTGCAGGAAACCTTGGACAACGGTAAACCGATTCGTGAAACCAGAGC
GGCGGATATTCCGTTGGCTTCCGATCACTTCCGTTATTTCGCCAGTGCGATTCGTGCCGGCGAAGGCAGCTTAAATCAAA
TCAATCAAGAAGAACTCTCGCTCGTATTACGTGAGCCGATCGGTGTAGTCGGACAAATTATTCCGTGGAACTTCCCGTTC
TTAATGGCGGCGTGGAAAATCGCACCGGCATTGGCGGCAGGTTGTACCGTGGTCATTCACCCTTCCAGCACCACTTCGTT
AAGTCTGTTATCTTTTGCGCAAAAAATTAACCATTTACTCCCGAAAGGCGTATTAAACGTAATTACCGGTAAAGGTTCTA
AATCCGGCGAATATATGTTACATCACAAAGGCTTCAATAAATTAGCCTTCACCGGTTCAACTGAAATCGGTCGTCATATT
GCGATTTCTGCGGCGGAATTACTCATTCCGGCAACCTTAGAATTAGGCGGTAAATCGGCTAATATTTTCTTTGACGATAT
GCCGTTTGATAAAGCGTTGGAAGGTGCGCAAAAAGGTATTTTATTCAACCAAGGACAAGTATGTTGCGCCGGTTCTCGTA
TCTTCGTACAAGAAGGGATTTACGACAAATTTGTGGCGGCACTCGCCGAAGAATTTAAGAAAGTCAAAGTCGGTTTACCA
TGGGAAGACGATACGCAAATGGGTGCGCAGGTCAATGCGGGACAACTTAACACTATCTTAAAATATGTGAAAATCGGTGA
AGAAGAAGGCTGTCGTATTATTACCGGCGGTAGAAAAGTGTTATCCGACAACCTTGCTTGCGGCGAATTCGTCGAGCCGA
CCTTAATCGAATCGAAAGATAATAACAGCCGTATCGCTCAAGAAGAAATCTTCGGACCGGTGGCAACCGTGATTAAATTC
AAAACCGAAGAAGACGTTATCCGTATGGCAAACGATTCGGAATACGGCTTAGGCGGCGGTGTTTGGACCAAAGACATCAA
CCGCGCGTTACGTGTTTCACAAGCAATCGAAACCGGTCGTGTTTGGGTAAACTGCTATAATATTCTACCGGCGGGCGCAC
CGTTCGGCGGTTATAAATCTTCCGGTATCGGACGTGAAACCCACCAAATGATGTTGGATGCTTACACCCAAGTGAAAAAT
ATCTACATCAGTACCCGTGAAGAACGTGAAGGAATGTATTAA

Protein sequence :
MKDLNVFDKNYGLLINGKWTQGSGNDLLPSYNPANGEVLAHFVDATDADVDAAVKAAQEAFKSWRKTTVAERAAILNKIA
DVIDENSELFALQETLDNGKPIRETRAADIPLASDHFRYFASAIRAGEGSLNQINQEELSLVLREPIGVVGQIIPWNFPF
LMAAWKIAPALAAGCTVVIHPSSTTSLSLLSFAQKINHLLPKGVLNVITGKGSKSGEYMLHHKGFNKLAFTGSTEIGRHI
AISAAELLIPATLELGGKSANIFFDDMPFDKALEGAQKGILFNQGQVCCAGSRIFVQEGIYDKFVAALAEEFKKVKVGLP
WEDDTQMGAQVNAGQLNTILKYVKIGEEEGCRIITGGRKVLSDNLACGEFVEPTLIESKDNNSRIAQEEIFGPVATVIKF
KTEEDVIRMANDSEYGLGGGVWTKDINRALRVSQAIETGRVWVNCYNILPAGAPFGGYKSSGIGRETHQMMLDAYTQVKN
IYISTREEREGMY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-97 52
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-100 50
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-100 50
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-100 50
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-100 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldA YP_001054690.1 aldehyde dehydrogenase aldA VFG0082 Protein 4e-98 52