Gene Information

Name : nanE (APL_1752)
Accession : YP_001054441.1
Strain : Actinobacillus pleuropneumoniae L20
Genome accession: NC_009053
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine-6-phosphate 2-epimerase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG3010
EC number : 5.1.3.9
Position : 1989491 - 1990180 bp
Length : 690 bp
Strand : +
Note : Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate

DNA sequence : 
ATGTCAAAGTTATCTCATTCGGAAGTATTGAATACGATTCGAAACGGTTTAATCGCTTCGTGTCAGCCGGTTGATGACGG
CCCGATGGACAAACCGGAGATCGTGGCGGCGATGGCGCAAGCCTCGCTTATCGGCGGTGCGGCAGGATTACGCATTGAAG
GGGTCGATAATTTAAAAGCGACTCGTCCGACGGTGAAAGCGCCGATTATTGCGATTGTAAAACGTGATTTACCGGATAGT
CCGGTACGTATTACGCCGTTTTTACAAGATATTGATGATCTGGCTGCAGCCGGTGCCGATATTATTGCGGTGGACGGTAC
GGATCGTGTTCGACCGGTCACGATTGAAGCGGCGTTGAAACGTATTCATGAGCTAGGTTGTTTGGCAATGGCGGACTGTT
CGACATTAGCAGAGGGTTTATATTGCCAGCAACTCGGTTTTGATATTGTCGGTAGCACAATGTCGGGTTATACCGGCGGA
GAAGTACCGAATGAACCGGATTATCAGTTAGTTAAAGACTTAAAAGCGGCGGGCTGTTTTGTGATGGCGGAAGGGCGTTA
TAACTCACCGCAACTGGCAAAAACCGCGATTGAAATCGGTGCGGATTGTGTTACGGTCGGTTCGGCACTCACTCGCTTGG
AGCATATTGTCGGCTGGTTTGCTGATGAGATAAAAACTGCGAAAGTTTAA

Protein sequence : 
MSKLSHSEVLNTIRNGLIASCQPVDDGPMDKPEIVAAMAQASLIGGAAGLRIEGVDNLKATRPTVKAPIIAIVKRDLPDS
PVRITPFLQDIDDLAAAGADIIAVDGTDRVRPVTIEAALKRIHELGCLAMADCSTLAEGLYCQQLGFDIVGSTMSGYTGG
EVPNEPDYQLVKDLKAAGCFVMAEGRYNSPQLAKTAIEIGADCVTVGSALTRLEHIVGWFADEIKTAKV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1378 YP_001217321.1 N-acetylmannosamine-6-phosphate 2-epimerase Not tested VPI-2 Protein 1e-45 56
VC1781 NP_231416.1 N-acetylmannosamine-6-phosphate 2-epimerase Not tested VPI-2 Protein 7e-46 56
nanE ACA01846.1 N-acetylmannosamine-6-phosphate epimerase Not tested VPI-2 Protein 2e-46 56

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
nanE YP_001054441.1 N-acetylmannosamine-6-phosphate 2-epimerase VFG1114 Protein 3e-46 56