Gene Information

Name : apxIC (APL_1445)
Accession : YP_001054134.1
Strain : Actinobacillus pleuropneumoniae L20
Genome accession: NC_009053
Putative virulence/resistance : Virulence
Product : RTX-I toxin-activating lysine-acyltransferase ApxIC
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2994
EC number : 2.3.1.-
Position : 1656005 - 1656523 bp
Length : 519 bp
Strand : -
Note : pubmed:8359891

DNA sequence : 
ATGAGTAAAAAAATTAATGGATTTGAGGTTTTAGGAGAGGTGGCATGGTTATGGGCAAGTTCTCCTTTACATCGAAAGTG
GCCGCTTTCTTTGTTAGCAATTAATGTGCTACCTGCGATTGAGAGTAATCAATATGTTTTGTTAAAGCGTGACGGTTTTC
CTATTGCATTTTGTAGCTGGGCAAATTTGAATTTGGAAAATGAAATTAAATACCTTGATGATGTTGCCTCGCTAGTTGCG
GATGATTGGACTTCCGGCGATCGTCGATGGTTTATAGATTGGATAGCACCGTTCGGAGACAGTGCCGCATTATACAAACA
TATGCGAGATAACTTCCCGAATGAGCTGTTTAGGGCTATTCGAGTTGATCCGGACTCTCGAGTAGGGAAAATTTCAGAAT
TTCATGGAGGAAAAATTGATAAGAAACTGGCAAGTAAAATTTTTCAACAATATCACTTTGAATTAATGAGTGAGCTAAAA
AATAAACAAAATTTTAAATTTTCATTAGTAAATAGCTAA

Protein sequence : 
MSKKINGFEVLGEVAWLWASSPLHRKWPLSLLAINVLPAIESNQYVLLKRDGFPIAFCSWANLNLENEIKYLDDVASLVA
DDWTSGDRRWFIDWIAPFGDSAALYKHMRDNFPNELFRAIRVDPDSRVGKISEFHGGKIDKKLASKIFQQYHFELMSELK
NKQNFKFSLVNS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlyC CAD42040.1 HlyC protein Virulence PAI II 536 Protein 1e-61 75
hlyC NP_755444.1 hemolysin C Virulence PAI I CFT073 Protein 7e-61 75
hlyC CAD33758.1 hemolysin C Virulence PAI I 536 Protein 7e-62 73

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
apxIC YP_001054134.1 RTX-I toxin-activating lysine-acyltransferase ApxIC VFG1559 Protein 5e-62 75
apxIC YP_001054134.1 RTX-I toxin-activating lysine-acyltransferase ApxIC VFG0905 Protein 2e-61 75
apxIC YP_001054134.1 RTX-I toxin-activating lysine-acyltransferase ApxIC VFG1499 Protein 3e-62 73
apxIC YP_001054134.1 RTX-I toxin-activating lysine-acyltransferase ApxIC VFG0842 Protein 9e-57 67