Gene Information

Name : apxID (APL_1442)
Accession : YP_001054131.1
Strain : Actinobacillus pleuropneumoniae L20
Genome accession: NC_009053
Putative virulence/resistance : Virulence
Product : RTX-I toxin secretion component
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1566
EC number : -
Position : 1649278 - 1650714 bp
Length : 1437 bp
Strand : -
Note : -

DNA sequence :
ATGAAAACATGGCTAATGGGTTTATATGAGTTTTTCCAACGCTATAAAACGGTTTGGACGGAGATCTGGAAAATTCGTCA
TCAATTGGATACGCCGGATCGAGAAAAGGATGAAAATGAATTTTTACCTGCACACTTAGAGCTGATTGAAACACCGGTGT
CAAAAAAACCGAGATTGATCGCTTATTTAATTATGCTGTTCCTATTTTTGGCATTAGTTATTTCAATTGTCAGTCACGTA
GAAATTGTGGCGACCGCAACGGGCAAATTAGCGTTTAGCGGACGTAGCAAAGAAATTAAGCCGATTGAAAACGCCTTGGT
TAAAGAAATCTTTGTGCAAGACGGACAATTTGTTGAGAAAGATCAGTTGCTGTTACACTTGACCGCATTGGGAGCCGATG
CGGATCAACAAAAAACCAAAAGTTCGTTATCGCTGACTAAATTGGAACGTTATCGTTATGAAATTTTATTAGAGGCGGTT
GCGGCGGATAGGTTGCCGCTCATTGAACTGACAAAGGATGAATTTAAACATGCTACGGAAGAAGATAAAACCAGAATTCG
CTATTTGATCACCGAGCAATTTGAAGCTTGGCAAAAGCAAAAGTATCAAAAAGAATTAGCTTTGCAACGTAGAGAAGCAG
AAAAACAAACGGTTCTAGCTAATATTCGTAAATATGAGGGAATCAGTCGAGTTGAAAATGAAAGATTAAAAGATCTTAAA
AAATTATTTAATTCGAAATCGACTTCTAAACATGATGTCTTGACTCAAGAAAATCGTCATATCGAAGCGGTAAATGAGTT
GGCGGTGTATAAATCTCGGTTGAATGAAGTGGAAAGTGACTTACGTCAAGCCAAAGAGGAAATACATTTAATAACTCAGT
TGTTTAGAGCCGATATTCTGGAGAAGTTGAAACAAAATGTTGAAGCGGAGAAACAGCTTTCGCTCGAATTAGAAAAAAAT
GAGCAGCGTCAAATTGCTTCGGTGATTCGTGCGCCGGTTTCCGGTACGGTTCAGCAACTTAAAACCCATACGGTAGGCGG
CGTCGTGACGACTGCCGAAACCTTGATGGTAATTGCTCCGGAAGATGATGTTTTAGAGGTAACGGCGTTAATTCAAAATA
AGGATATTGGTTTTATCGAGGTCGGTCAGGATGCGGTGATTAAAGTAGAAACTTTTCCTTATACTCGTTACGGCTATTTA
ATGGGTAAAGTAAAAAATATCACGCTGGAAGCCATCGAACATCCGCAACTCGGCCTAGTTTTTAACTCGATTATTTCTAT
TGATAGAAAAACTTTATCCGGCAAAGACGGCAAAGAAATTGAACTTGGATCAGGTATGAGTGTGACGGCGGAAATTAAAA
CTGGAGAACGTAGCGTTATTAGTTATTTACTCAGTCCGTTGGAAGAATCCGTTTCGGAGAGTTTAAGAGAACGCTAA

Protein sequence :
MKTWLMGLYEFFQRYKTVWTEIWKIRHQLDTPDREKDENEFLPAHLELIETPVSKKPRLIAYLIMLFLFLALVISIVSHV
EIVATATGKLAFSGRSKEIKPIENALVKEIFVQDGQFVEKDQLLLHLTALGADADQQKTKSSLSLTKLERYRYEILLEAV
AADRLPLIELTKDEFKHATEEDKTRIRYLITEQFEAWQKQKYQKELALQRREAEKQTVLANIRKYEGISRVENERLKDLK
KLFNSKSTSKHDVLTQENRHIEAVNELAVYKSRLNEVESDLRQAKEEIHLITQLFRADILEKLKQNVEAEKQLSLELEKN
EQRQIASVIRAPVSGTVQQLKTHTVGGVVTTAETLMVIAPEDDVLEVTALIQNKDIGFIEVGQDAVIKVETFPYTRYGYL
MGKVKNITLEAIEHPQLGLVFNSIISIDRKTLSGKDGKEIELGSGMSVTAEIKTGERSVISYLLSPLEESVSESLRER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlyD CAD33761.1 Hemolysin D Virulence PAI I 536 Protein 3e-144 64
hlyD CAD42037.1 HlyD protein Virulence PAI II 536 Protein 3e-144 64
hlyD NP_755449.1 hemolysin D Virulence PAI I CFT073 Protein 4e-144 64
hlyD AAC61717.1 chromosomal hemolysin D Virulence PAI I CFT073 Protein 3e-128 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
apxID YP_001054131.1 RTX-I toxin secretion component VFG1556 Protein 2e-144 64
apxID YP_001054131.1 RTX-I toxin secretion component VFG0908 Protein 2e-144 64
apxID YP_001054131.1 RTX-I toxin secretion component VFG1502 Protein 2e-144 64
apxID YP_001054131.1 RTX-I toxin secretion component VFG0843 Protein 9e-106 50