Gene Information

Name : pepA (APL_1101)
Accession : YP_001053798.1
Strain : Actinobacillus pleuropneumoniae L20
Genome accession: NC_009053
Putative virulence/resistance : Unknown
Product : leucyl aminopeptidase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0260
EC number : 3.4.11.1
Position : 1272039 - 1273538 bp
Length : 1500 bp
Strand : -
Note : catalyzes the removal of N-terminal amino acids preferably leucine from various peptides

DNA sequence :
ATGGAATTTAGCGTAAAAAACGGTAGTGTCGAAAAACAACGTACTGCCTGTTTAGTGGTCGGCGTGTACGAGCCTCGCCG
TTTATCTGCGGCGGCAGAACAATTAGACAAGTTAAGTGAAGGCTATATCAGCACGTTATTACGTCGTGGCGATTTGGAAG
GCAAGGCGGGGCAAACGCTTTTACTGCATAATGTACCTAACGTACCTGCTGATCGCGTGTTATTGGTCGGTTGCGGAAAA
GAAAGAGAATTAACCGAACGCCAATATAAACAAATTATTCAAAAAATGGTACAAGCCGTCAGTGAAACGGGTTCGATGGA
AGTAGTTTGTTTTCTGACCGAATTACACGTAAAAGGTCGTACAAGTTATTGGAATGTTCGTTTTGCGATTGAAGCGATTC
AAGAAAGTTTATACAGCTATAACGATTTCAAAAGCATTAAGCCGGAAGTGCGCCGAGAATTCCGTCGTGTGATTTTTAAC
GTCGCGAACCGTAAGGATTTAGCCGATGCGGAACGTGCGTTAGAACACGGTAAAGCGATCTCAACCGGTGTTGCCTTTGC
GAAAAACGTCGCAAACTGCCCGCCGAACGTTTGTAATCCGGCGTATCTTGCCGAATTGGCAAAAGGCTTAGCCGCAGAAT
ATGACAATATTCGTACCACGGTAATTGATGAAGCGGAAATGGCGGCATTAGGGATGAATGCTTATTTGGCGGTTTCGCGC
GGTTCGCAGAATCCGGCGTATTTATCGGTAATCGAATATAAAAATCATCCGAATCCCGATGCCAAACCAATCGTCTTAGT
GGGTAAAGGACTGACTTTCGACTCGGGCGGTATTTCGATTAAACCGTCCGATTCAATGGATGAAATGAAATATGATATGG
GCGGTGCCGCTTCGGTTTACGGTACGATGAAAGCGTTAGCGGAAATGAAATTACCGCTGAACGTTATCGGCGTGCTGGCA
GGCTGTGAGAATATGCCGGACGGCAATGCCTATCGCCCGGGAGATATTCTGACTACGATGAACGGTTTAACCGTAGAAGT
GTTGAATACCGATGCGGAAGGTCGTTTAGTGCTGTGTGATACGCTGACTTATGTAGAACGCTTCGAGCCGGAACTGGTCA
TTGATATGGCAACGCTGACCGGTGCTTGTATGATTGCGTTAGGTGCGCATAACAGCGGTTTGATGTCCACCAGTAACGTA
TTGGCAAACGAATTATTAAATGCGGCGGAACAAGCGGACGATAAAGCGTGGCGTTTACCGTTAGGCGAAGAATATCAAGA
ACAGCTTAAATCTAACTTTGCCGATTTAGCCAATATCGGCGGACGTTTAGGCGGAGCGATTACTGCAGGGCAGTTCTTAT
CGAACTTTACCAAAAAATATAGTTGGGCGCATTTGGATATCGCCGGTACGGCTTGGAAGTCCGGTGCGGCAAAAGGTGCA
ACCGGAAGACCGGTTTCACTGTTAAGCCAATTCTTGATTAATAAAGCAAATAATCAATAA

Protein sequence :
MEFSVKNGSVEKQRTACLVVGVYEPRRLSAAAEQLDKLSEGYISTLLRRGDLEGKAGQTLLLHNVPNVPADRVLLVGCGK
ERELTERQYKQIIQKMVQAVSETGSMEVVCFLTELHVKGRTSYWNVRFAIEAIQESLYSYNDFKSIKPEVRREFRRVIFN
VANRKDLADAERALEHGKAISTGVAFAKNVANCPPNVCNPAYLAELAKGLAAEYDNIRTTVIDEAEMAALGMNAYLAVSR
GSQNPAYLSVIEYKNHPNPDAKPIVLVGKGLTFDSGGISIKPSDSMDEMKYDMGGAASVYGTMKALAEMKLPLNVIGVLA
GCENMPDGNAYRPGDILTTMNGLTVEVLNTDAEGRLVLCDTLTYVERFEPELVIDMATLTGACMIALGAHNSGLMSTSNV
LANELLNAAEQADDKAWRLPLGEEYQEQLKSNFADLANIGGRLGGAITAGQFLSNFTKKYSWAHLDIAGTAWKSGAAKGA
TGRPVSLLSQFLINKANNQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00295 YP_008207760.1 Leucyl aminopeptidase Not tested AbaR25 Protein 6e-81 55
BJAB0868_00299 YP_008211625.1 Leucyl aminopeptidase Not tested AbaR26 Protein 6e-81 55