Gene Information

Name : clpB (APL_1087)
Accession : YP_001053784.1
Strain : Actinobacillus pleuropneumoniae L20
Genome accession: NC_009053
Putative virulence/resistance : Virulence
Product : chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1257302 - 1259875 bp
Length : 2574 bp
Strand : +
Note : -

DNA sequence :
ATGAATTTCGAAAAATTTACTACCAAATTGCAAGAAGCCCTTGCAGAAGCACAATCGTTAGCTATCGGAAAAGATAATAA
CTATATTGAACCGGCACATTTACTTTATGCGTTAGTCAAACAACCGGACGGCTCTATCGCCCCGCTATTTACTGCACTTA
ATGTACAACCGCAACGTATTTTGAGTGAATTAGAGACGATTTTAAACCGCTTACCGACCGTATCCGGCGGTACAACCCAA
CCGTCACAACAATTAATTCGCCTGTTAAATCAATGCGATAAACTAGCGCAGCAATTCGGTGACAGCTTTATTTCATCGGA
ATTATTCGTGCTTGCCGCACTGGACGATAACGGCGATTTAGGCAAATTATTAAAACAATTTGGCTTGACTAAAGAAAAAG
TAAACGCAGCCATCAGCCAAATTCGAGGAGGAGAAAACGTGAATAATCAAAACGCAGAAGAAACCAGACAGGCCCTTCAA
AAATATACTATCGATCTCACAGAAAGAGCCAAAGCCGGTAAATTAGATCCGGTCATCGGGCGTGATGAAGAAATCCGCCG
TGCAGTACAAGTTTTACAACGCCGTACTAAAAATAACCCGGTATTAATCGGTGAACCTGGGGTCGGTAAAACTGCGATCG
TAGAAGGCTTGGCACAACGTATCGTCAACGGCGAAGTGCCGGAAGGTTTAAAAAATAAACGTGTACTTTCTCTCGATATG
GGCGCATTAATTGCTGGTGCAAAATATCGCGGCGAATTTGAAGAACGTCTAAAAGCGGTACTTAACGAATTAGCCAAAGA
AGAAGGTCAGGTTATCTTATTTATTGATGAAATTCACACCATGGTCGGTGCGGGTAAAACAGACGGCGCAATGGATGCCG
GTAACTTACTCAAGCCGTCACTTGCTCGCGGCGAATTACATTGCGTTGGGGCAACTACGTTAGACGAATACCGCCAATAT
ATCGAAAAAGATGCGGCACTTGAACGTCGTTTCCAAAAAGTATTAGTGGACGAACCGACCGTTGAGGATACGATTGCAAT
TTTACGCGGCTTGAAAGAACGTTATGAAATTCATCACCACGTACAAATTACCGACCCGGCAATTGTCGCGGCGGCAACGC
TTTCGCACCGTTATATTTCCGACCGCCAATTACCGGATAAAGCGATCGATTTAATTGATGAAGCCGCATCCAGTTTACGT
ATGGAAATCGATTCTAAACCTGAGCCGTTGGATAAACTTGAACGCCGTATTATTCAACTTAAATTGGAACGCCAAGCGTT
ACAAAAAGAGGAAGATGAAGCAAGCCGCCAACGTCTTGCAAAATTAGATGAAGAATTGACCGCTCGCGAGCGTGAATATT
CCGAATTGGAAGAAGTTTGGAAAGCGGAGAAATCAGCATTACTCGGTACGCAACATATCAAAACCGAGTTAGAAAATGCC
CGTATCGAAATGGATCAGGCTCGCCGTGAAAATAATTTCGAGAAAATGTCCGAATTGCAATACGGTAAAATTCCGGCATT
GGAAAAACAATTACACGAAGCGGTAAAACGCGAGGAAGAAGGCAGTGAAAATCAACTGCTTCGTACCAAAGTCACCGAGG
AGGAAATCGCAGAAGTGCTTTCAAAAGCGACCGGTATTCCGGTTTCCAAAATGATGGAAGGCGAAAAAGAAAAACTATTG
CGTATGGAAGAAGTGTTACACAGCCGTGTCATCGGACAAAATGAAGCGGTAGAAGCGGTGGCAAATGCAATTCGCCGTAG
CCGTGCCGGATTGTCGGATCCGAATCGTCCGATCGGTTCGTTCTTATTCCTTGGCCCGACCGGGGTCGGTAAGACCGAAC
TTTGCAAAACCTTGGCGAATTTCCTATTCGATGATCCTGATGCGATGGTACGTATCGATATGTCGGAATTTATGGAAAAA
CACAGCGTTTCTCGTTTAGTCGGCGCACCTCCGGGCTATGTCGGTTATGAAGAAGGCGGTTATTTAACCGAAGCGGCTCG
CCGCCGTCCATATTCGGTAGTATTACTCGATGAAGTGGAAAAAGCGCACCCTGACGTGTTTAATATCTTGCTTCAAGTGT
TGGATGACGGTCGTTTAACCGACGGTCAAGGTCGTACGGTGGATTTTCGTAATACGGTAGTAATTATGACTTCAAACTTA
GGTTCACATTTAATCCAAGAAAATCCGGAATTAGATTATGCTGGAATGAAAGAAGTAGTGATGTCAGTGGTAGGACAACA
TTTCCGTCCTGAATTTATCAACCGTATTGATGAAACTGTGGTGTTCCACCCACTTGGTCAAGCACATATCCGTGCGATTG
CTCGCATTCAGTTACAACGTTTAATCGCTCGCCTTGCGGAACGCGGTTACGAAGTAACAGTTACCGATGCGGCATTAGAC
CATATCGGCAAAGCCGGCTTTGACCCGTTATTCGGTGCAAGACCGCTCAAACGTGCGATTCAGCAAGAGCTTGAAAATCC
GCTTTCACAACAGATCTTAAGCGGCAAATTATTACCGAACAGCCCAGTTGTGGTGGACTATCAAAATGACCGATTAAGCA
TTAGCAACAGCTAA

Protein sequence :
MNFEKFTTKLQEALAEAQSLAIGKDNNYIEPAHLLYALVKQPDGSIAPLFTALNVQPQRILSELETILNRLPTVSGGTTQ
PSQQLIRLLNQCDKLAQQFGDSFISSELFVLAALDDNGDLGKLLKQFGLTKEKVNAAISQIRGGENVNNQNAEETRQALQ
KYTIDLTERAKAGKLDPVIGRDEEIRRAVQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSLDM
GALIAGAKYRGEFEERLKAVLNELAKEEGQVILFIDEIHTMVGAGKTDGAMDAGNLLKPSLARGELHCVGATTLDEYRQY
IEKDAALERRFQKVLVDEPTVEDTIAILRGLKERYEIHHHVQITDPAIVAAATLSHRYISDRQLPDKAIDLIDEAASSLR
MEIDSKPEPLDKLERRIIQLKLERQALQKEEDEASRQRLAKLDEELTAREREYSELEEVWKAEKSALLGTQHIKTELENA
RIEMDQARRENNFEKMSELQYGKIPALEKQLHEAVKREEEGSENQLLRTKVTEEEIAEVLSKATGIPVSKMMEGEKEKLL
RMEEVLHSRVIGQNEAVEAVANAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLANFLFDDPDAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAARRRPYSVVLLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSHLIQENPELDYAGMKEVVMSVVGQHFRPEFINRIDETVVFHPLGQAHIRAIARIQLQRLIARLAERGYEVTVTDAALD
HIGKAGFDPLFGARPLKRAIQQELENPLSQQILSGKLLPNSPVVVDYQNDRLSISNS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 8e-110 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_001053784.1 chaperone ClpB VFG2076 Protein 7e-111 44
clpB YP_001053784.1 chaperone ClpB VFG2084 Protein 7e-112 41