Gene Information

Name : APL_1043 (APL_1043)
Accession : YP_001053742.1
Strain : Actinobacillus pleuropneumoniae L20
Genome accession: NC_009053
Putative virulence/resistance : Unknown
Product : aminotransferase AlaT
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0436
EC number : 2.6.1.2
Position : 1211431 - 1212648 bp
Length : 1218 bp
Strand : +
Note : broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor

DNA sequence :
ATGGAACGTTTCCCTAAATCAGACAAGCTCGCAAACGTTCGTTACGATATTCGTGGCGCAATACATAAAGAAGCTCTTCG
TTTAGAAGAAGAGGGTAATAAAATTTTAAAATTGAATATCGGTAATCCCGCCCCGTTTGGTTTTGAAGCCCCGGACGAAA
TAGTTGTCGATGTCATTCGCAATTTACCGAAATCGCAGGGTTATTGCGACTCCAAAGGCTTATATTCGGCACGTAAAGCG
ATCGTACAATATTATCAATCGAAAGGTATTCGTAACGTCGATGTCAATGACGTCTATATCGGTAACGGCGTATCGGAATT
AATTACAATGTCGATGCAAGCCTTGCTGAATGACGGCGACGAAATGTTAATTCCGATGCCGGATTACCCGCTTTGGACTG
CGGCGGCAACCCTTGCCGGCGGTAAAGCGGTGCATTATTTATGTGATGAAAACAATGAATGGATGCCGGATATTGAGGAT
ATTAAAGCGAAAATTACCCCTCGTACCAAAGGGATTTTAGTCATTAACCCGAATAATCCGACCGGTGCGGTTTACAGCCG
CTCGATGTTACTTGAGATTGCGGAAATCGCTCGCCAGCACAATTTAATGATTTTTGCGGACGAAATTTACGAGAAAATTA
TTTATGACGGAGCGGTACATCATCATATTGCCGCACTTGCACCGGATTTATTATGCGTAACCTATAACGGCTTATCGAAA
GCCTACCGTGTCGCCGGTTTCCGTCAAGGTTGGATGGTATTAAGCGGTCCGAAAAACCAAGCGAGAGGTTTTATTGAAGG
TTTGGATATGCTCGCTTCCATGCGTTTATGTGCGACAACCCCGATGCAGCACGCGATTCAAACGGCATTAGGCGGTTATC
AAAGTATCAACGAATTCGTATTGCCGGGCGGTCGTTTACTCGAACAACGTAATAAAATGTATGAGTTGTTGGTACAAATT
CCGGGAATTTCTTGTGTGAAAGCGAAAGGTGCGCTGTATATGTTCCCGAAAATTGACACGGAAATGTACGGTATCAAAGA
CGATGCCAAATTTATTTATGACTTATTACAGGCGGAAAGAGTGCTGTTAGTACAAGGTTCCGGCTTTAACTGGCACAAAC
CGGATCACTTCCGTGTCGTAACCTTGCCTTATGCGCACCAAATTGAAGAAGCATTAGGGCGTCTTGCCAACTTCTTAAAA
ACCTATAAACAATCTTAA

Protein sequence :
MERFPKSDKLANVRYDIRGAIHKEALRLEEEGNKILKLNIGNPAPFGFEAPDEIVVDVIRNLPKSQGYCDSKGLYSARKA
IVQYYQSKGIRNVDVNDVYIGNGVSELITMSMQALLNDGDEMLIPMPDYPLWTAAATLAGGKAVHYLCDENNEWMPDIED
IKAKITPRTKGILVINPNNPTGAVYSRSMLLEIAEIARQHNLMIFADEIYEKIIYDGAVHHHIAALAPDLLCVTYNGLSK
AYRVAGFRQGWMVLSGPKNQARGFIEGLDMLASMRLCATTPMQHAIQTALGGYQSINEFVLPGGRLLEQRNKMYELLVQI
PGISCVKAKGALYMFPKIDTEMYGIKDDAKFIYDLLQAERVLLVQGSGFNWHKPDHFRVVTLPYAHQIEEALGRLANFLK
TYKQS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aspC YP_005682179.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-129 65
aspC YP_005684271.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-129 65
aspC YP_003784329.1 aspartate aminotransferase Not tested PiCp 7 Protein 2e-129 65
aspC YP_005686363.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-129 65