Gene Information

Name : cvrA; nhaP2; ycgO (Memar_0908)
Accession : YP_001046823.1
Strain : Methanoculleus marisnigri JR1
Genome accession: NC_009051
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 885887 - 887380 bp
Length : 1494 bp
Strand : +
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
ATGATACTCACCCTCGAACTCATGCTCGTCGGCATAGCGTTGCTCTTCCTGATCAGCATCGTTGCAAACAAGTTTTCAGA
GCGGCTCGGCGTCCCTGCACTTCTCATCTTCCTCGTCGTCGGGATGCTCGCGGGTTCCGAGGGTCCGGGCGGCATTCCGT
TCGACGACCCTGCGATTGCGCAGATCATCGGGATTGTTGCACTTGCATACATCCTCTTCTCCGGCGGTCTCGACACCCGG
TGGGAGCAGATCCAGCCTATCCTCTGGCCGGGCATCGCCCTCTCCACGGTCGGCGTTGTTCTGACCGCAAGCCTGCTCGG
CGGGTTTGCCGTTCTGGTCTTCGGTTTTTCCCCGCTGACGGGCCTTCTCCTCGGTTCGGTCGTCGCGTCCACCGATGCTG
CGGCGGTCTTTTCGGTTCTGCGGACGGCAAGGGCACGCCTCCAGGGAAACCTGCGGCCGCTGCTCGAGCTTGAGTCGGGG
AGCAACGATCCCGTGGCCGTCCTTCTCACCATCGGTATCATCGGCGTGATCCTTATCCCGGGCACGTCGCTACTCGCCGT
CGTCCCGATGTTCGTGCAGCAGATGGCGGTCGGGGGCCTGTTCGGCTACGGGATGGGGCATGCCGTCGTTTTCCTCATCA
ACCGTCTCAAGCTGGAGTTCGAGGGGTTGTATCCGGTGCTCAGCCTCACGATGGTGCTGCTGACCTACGGCCTGACCGCC
ACCCTCGGAGGAAACGGATTCCTCGCGGTTTACATAGCCGGGCTGATCATGGGCAACAGCATCGTCCTTCATAAAAAGAG
CCTGATCCGGTTCCACGACGGGATCGCGTGGCTGATGCAGATCGTGATGTTCCTTGCGCTCGGCCTGCTCGTCTTCCCCT
CGTCTCTCCTGCCGGTGGCCGTTCCCGGTATTCTCGCAGCCCTCTTCCTGCTCCTGGTCGCACGGCCGGTCGCCGTCATG
ATCACGCTGCTCCCCTGGAAGATGCCGATCAGAGAGAAGGCCCTGATCTCCTGGGTGGGGCTGCGGGGAGCCGTCCCGAT
CATCCTCGCGACCTATCCGCTTGTTGCGGGTGTGCCGAACGCAGAGGCGATCTTCAACCTCGTCTTCTTCATCGTCCTCG
TCTCGGCGCTGGTTCACGGGACGTCGATCCCCTCCGTCGCCCGTTGGCTCGGCCTCGCCGCCCCGCTCGAGGAGACGCGC
AAACTCTCCCGGGAGTTCGACGTGAACCCCGATACCCCGAGCGAGCTGCTCGAACTGGTCATCCCTCCGGACGCCTCGGC
GGTGGGAAAACAGGTCGTCGACCTCGGGTTGCCGAAGGGCGCCCTCATCATCCTGATGCAGAAAGGAGACGAACGGTTTG
TCCCGGGCGGCAGCACCGTCATCGAGGCCGGAGATACGCTTCTCTTCCTGACGACCGGGGACCTTGCGGACACCGTCCGC
ACCAGGCTTCTCTGCAGAGAGGAGCCGGAGGACGTTCCCGGCCCTGATGCCTGA

Protein sequence :
MILTLELMLVGIALLFLISIVANKFSERLGVPALLIFLVVGMLAGSEGPGGIPFDDPAIAQIIGIVALAYILFSGGLDTR
WEQIQPILWPGIALSTVGVVLTASLLGGFAVLVFGFSPLTGLLLGSVVASTDAAAVFSVLRTARARLQGNLRPLLELESG
SNDPVAVLLTIGIIGVILIPGTSLLAVVPMFVQQMAVGGLFGYGMGHAVVFLINRLKLEFEGLYPVLSLTMVLLTYGLTA
TLGGNGFLAVYIAGLIMGNSIVLHKKSLIRFHDGIAWLMQIVMFLALGLLVFPSSLLPVAVPGILAALFLLLVARPVAVM
ITLLPWKMPIREKALISWVGLRGAVPIILATYPLVAGVPNAEAIFNLVFFIVLVSALVHGTSIPSVARWLGLAAPLEETR
KLSREFDVNPDTPSELLELVIPPDASAVGKQVVDLGLPKGALIILMQKGDERFVPGGSTVIEAGDTLLFLTTGDLADTVR
TRLLCREEPEDVPGPDA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 2e-44 42
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 2e-44 42