Gene Information

Name : Memar_0811 (Memar_0811)
Accession : YP_001046726.1
Strain : Methanoculleus marisnigri JR1
Genome accession: NC_009051
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 794833 - 796110 bp
Length : 1278 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTTGAGTTGAAGTTCGTTCGTGCACACCCCGAGATCGTCCGGGCAGACCTCACGAAGAGAGGAGACACCGAGAAACT
GGCCTGGGTCGACGAGGTGCTGGAGATGGACAGGAGGGCACGGGAACTCACCGTTGCGATCGGGGATCTCCGCAACCGGA
GAAACGTCATTTCCCGCGAGATCAGCCAGGCGAGGAAGGCGGGGAACGATATCACCGAACTCCTCGCCGAAGCCGCAGGC
CTCCCGGAACGGATCAAGGAGGTGGAGACGGAACGCGAGACGCTCACCGAAGCGGTACGCTACCGCCTGATGCGGCTCCC
GAACATCCTCCACGAGAGCGTGCCCGTCGGCAAGGACGACTCCGAGAACGTCGAGATCCGGCGATGGGGCGAACCGGAGA
TCCCTGCGTTCGACCTGGAGAACCACGGCGCGCTCGCCGTCGAGCACGGTTGGGCGGACTTCGAACGCGCGGCGAAGATT
GCCGGATCCGGGTTCTACTTCCTGAAGGGCAGGCTCGCCCTGCTCGATATGGCGCTCCAGCGGTTCGCGATGGATATCCT
CGTCGAACACGGGTATACCCCGATCATTCCGCCCTACATGATGAACCGGGCCGCATACGAGGGCGTGACCGACCTCGCCG
ACTTCGAGAACGTCATGTACAGGATCGACGGTGAGGACGAGTACCTCATCGCGACGAGCGAGCACCCGATGGCCGCGATG
TACTGCGACGAGATCTTCGAGGAGAAGGATCTGCCGCTCCGGCTTGCGGGGCTGAGCCCGTGTTTCCGCCGCGAGATCGG
GGCGCACGGGCTCGATACGAAAGGGCTCTTCCGGGTCCACCAGTTCCACAAGGTGGAGCAGTTCATCTACGCGACGCCGG
AGCAGTCCTGGGACCTTCACGAGGAACTGATGGCGAACGCCGAGGAGGTCTTCCAGCGGCTCGGCCTTCCCTACCGGATT
GTCTCGATCTGCACGGGAGATATCGGGACGGTCGCCGCGAAGAAGTACGACCTCGAGGTCTGGATGCCGCGCGAGGAGCG
CTACCGCGAAGCGGTCTCCTGCTCGAACTGCACGGCCTACCAGGCGGTTCGGCTGAACATCAAGGTGCGCAACCCGACCG
AGTTCACCGAGAAGCGCTACGTGCATACCCTGAACAGCACCGCGATCGCGACCTCCCGCGCGATCCGGGCGATCCTCGAG
AACAACCAGAACGAGGACGGCTCGGTCACGATCCCGAAGGCCCTCAGGCCCTACCTCTACGGCAGCGAGACGCTGTAA

Protein sequence :
MLELKFVRAHPEIVRADLTKRGDTEKLAWVDEVLEMDRRARELTVAIGDLRNRRNVISREISQARKAGNDITELLAEAAG
LPERIKEVETERETLTEAVRYRLMRLPNILHESVPVGKDDSENVEIRRWGEPEIPAFDLENHGALAVEHGWADFERAAKI
AGSGFYFLKGRLALLDMALQRFAMDILVEHGYTPIIPPYMMNRAAYEGVTDLADFENVMYRIDGEDEYLIATSEHPMAAM
YCDEIFEEKDLPLRLAGLSPCFRREIGAHGLDTKGLFRVHQFHKVEQFIYATPEQSWDLHEELMANAEEVFQRLGLPYRI
VSICTGDIGTVAAKKYDLEVWMPREERYREAVSCSNCTAYQAVRLNIKVRNPTEFTEKRYVHTLNSTAIATSRAIRAILE
NNQNEDGSVTIPKALRPYLYGSETL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-70 41