Gene Information

Name : Memar_0699 (Memar_0699)
Accession : YP_001046614.1
Strain : Methanoculleus marisnigri JR1
Genome accession: NC_009051
Putative virulence/resistance : Virulence
Product : UDP-glucose 6-dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : 1.1.1.22
Position : 679600 - 680859 bp
Length : 1260 bp
Strand : -
Note : PFAM: UDP-glucose/GDP-mannose dehydrogenase; 6-phosphogluconate dehydrogenase, NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: dvu:DVU3176 UDP-glucose/GDP-mannose dehydrogenase family protein

DNA sequence :
ATGATTCAGGGATCCGTGAACGATACAACCGTCTGCGTCGTCGGCCTGGGCTACGTCGGGTATCCCCTCGCCGATGCGTT
CTCGCGCCATCTCAAGACGATCGGTTACGACCTCGACGCGACGAAGATCGCGCGGATCAACGCCGAGCCCGGCAACAGGG
TCCTCGCCACCACGGATCCGGCCGCGATCAGGGAGGCGGACGTCGTGATCGTCGCCGTCCCCACCCCGGTGACGAAGGCG
AAAGACCCCGACATCTCCTACGTCGTCTCGGCCGCCGGGACCGTCGGTCAAAACCTCAGGGACGGCGCCGTCGTCGTCCT
CGAGTCGACCGTCTACCCCGGCCTGACCGAGGAGGTCGTGGTCCCGACCCTCGAACGGGCCTCCGGGAAGACCTGCGGAA
AGGACTTCTTCGTCGGCTACTCGCCCGAACGGATCAACCCGGGCGACACCGACCACACACTGGAGAAGATCACTAAGATC
GTCGCCGGGATGGATAAGGAGACGACAGAACGCCTTGCCGCGCTCTACGGCCTCGTGACCAACGTCTACGTCGCACAGGA
CATCCGGACCGCCGAGGCGGCGAAGGTGATCGAGAACGTCCAGCGGGACTTGAACATCGCCCTCATGAACGAACTCTCCC
TCATCTTTAGGAAGATGGGTCTCGAGACGAAGGCGGTGCTCGACGCCGCCGGGACGAAGTGGAACTTCCACAACTACCGC
CCCGGCCTCGTCGGCGGCCACTGCATCCCGGTCGACCCCTACTACCTGGTCTACAAGGCCGAGGAGCTCGGCTACCACCC
GCAGGTGATCCTGGCCGGCCGCGCGATCAACGACGCCATGCCCAAGCACGTCGCCGAGATCGCGATCAAGGAGCTGAACC
GGGCCGGCAAGGTGATCCGCGACTCGAACGTCCTCATCCTGGGCCTGACCTACAAGGAGAACGTCCCCGATACAAGGGAG
AGCCCGGCCGGGGAGATGGTCCGCGAACTCAAGGAGTTCGATGTGGATGTCTATGGCTACGACCCGCTCCTCGCGGCCGC
GGAGATCGAGCGGTTCGGGGCGAAGCCGGTCGCGTCGCTGCAGGGGCTCAGCGGGCCGGTGGACTGCATTATCGTGAATT
CTCCGCACGGGGTGTTTGTGGGGCTGACGTTGGAGAATGTGCTTGCGATCTGCAACGGGAAGCCTATTGTCGTGGACGTG
ACAGGGATGCTCCGGCGGAATAACGGGATGCGGGAGGGGTGTGTGTATTGTACGTTGTGA

Protein sequence :
MIQGSVNDTTVCVVGLGYVGYPLADAFSRHLKTIGYDLDATKIARINAEPGNRVLATTDPAAIREADVVIVAVPTPVTKA
KDPDISYVVSAAGTVGQNLRDGAVVVLESTVYPGLTEEVVVPTLERASGKTCGKDFFVGYSPERINPGDTDHTLEKITKI
VAGMDKETTERLAALYGLVTNVYVAQDIRTAEAAKVIENVQRDLNIALMNELSLIFRKMGLETKAVLDAAGTKWNFHNYR
PGLVGGHCIPVDPYYLVYKAEELGYHPQVILAGRAINDAMPKHVAEIAIKELNRAGKVIRDSNVLILGLTYKENVPDTRE
SPAGEMVRELKEFDVDVYGYDPLLAAAEIERFGAKPVASLQGLSGPVDCIIVNSPHGVFVGLTLENVLAICNGKPIVVDV
TGMLRRNNGMREGCVYCTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 1e-77 46
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-76 43
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-76 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Memar_0699 YP_001046614.1 UDP-glucose 6-dehydrogenase VFG0431 Protein 5e-77 43