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Name : lysS (Memar_2341) Accession : YP_001048246.1 Strain : Methanoculleus marisnigri JR1 Genome accession: NC_009051 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 2326708 - 2328234 bp Length : 1527 bp Strand : + Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : ATGAGCGATATGGATCACACCTGTTTTGACACGGCAAAGATCGATAAGTTACAGGAACTGCGCGAGCGCGGGGTGACGGT CTACCCCTACACCTTCGACCGCAGGGATACCGTCGAGGAGATCAAGGAGCGGTTCTCCGCGATCGAGCACGATAAGAGCG AGGAGGAGGTCAGCACCGCGGGGCGGGTCTACGTCGTCCGCCAGCACGGCAAGACGATCTTCGCCGATATCGGCGACTCC GAAGGCCGGATCCAGCTGTATCTGCGGAAGAACGACCTCGGCGAGGAGCAGTTCGACCTCTTCAAGCAGTACGTCGACGC CGGCGACATCGTCGGCGTCGTCGGCCACGTCTTCCGGACGAAAATGGGCGAGATCACCGTCTGGGTCGACCGGTTCGAAC TCCTTACGAAATCGGTCTGCCCGCTTCCCGAGAAGTTCCACGGGCTCAAGAACGTTGAGACCCGCTATCGGCAGCGCTAC CTCGACCTGATCATGAACGAGGAGAGCCGCGAGACCTTCAGGGCGCGGAGCAGGATCATCTCCCTCCTGCGACAGTTCCT CTTCGAGCGGGACTACCTGGAGTTCGAGACGCCCACCCTGCAGCCGATCTACGGCGGCGCGAACGCCCGGCCGTTCACCA CCCACCACAACGCCCTCGACCAGAAACTCTACCTCAGGATAGCGCCGGAACTCTACCTCAAACGCCTGGTCGTCGGCGGG TTCGATAAGGTCTTCGAGATCGCGAAGAACTTCAGGAACGAAGATATCGACACCAACCACAACCCCGAGTTCACGATGGT AGAGGTCTACGAGGCCTACCGCGACTACAACGACATGATGAACCTCACCGAGGAGATCCTCTCCCACCTCGCGGAGAAGG TGCTCGGGACGACCGTCTGCTCGTTCGCCGGGCACGACCTGGACTTCTCCCGCCCCTGGCGCCGCCTCACGATGGAGGAG GCGGTGCGGGAGTACGCCGGGATTGACTTCCCGGCCATGAGCCTCGAAGAACTCCACGCCTTCGGCCTCGAGCACTGCGT CGAGGGCTGCGAGAGCGCCGCGACCCGGGGCGAGTACCTGGTGCTCTTCTTCGAGCACTTCGGCGAGAAGCACCTCATCC AGCCGACATTCATCTACGACTTCCCGATCGAGAACTCGCCGCTCGCAAAGAAGCACCGCTCAAAAGAAGGGCTGACGGAG CGGTTCGAGCTCTTCATCGCCGGGATGGAGATGGCGAACGGCTTCTCGGAGTTAAACGACCCCCTCGACCAGAAAGCCCG GCTCGAACAGCAGGACGCGAAACGCCGGAAGGGCGACCTCGAGGCGCAGATGATCGACTACGACTTCATCAACGCGCTCG GCTACGGGATGCCTCCGACGGGCGGCGTCGGGATCGGGATCGACCGGCTGGTGATGCTCCTCACCGGCAAGGACTCGATC AAGGAGGTCCTCCTCTTCCCGCAGATGAAGACCGCCGTCCCCGGGCAGAACGGGGACAAAGCGGAAGAAGGCGATGGGGA AGAGTGA Protein sequence : MSDMDHTCFDTAKIDKLQELRERGVTVYPYTFDRRDTVEEIKERFSAIEHDKSEEEVSTAGRVYVVRQHGKTIFADIGDS EGRIQLYLRKNDLGEEQFDLFKQYVDAGDIVGVVGHVFRTKMGEITVWVDRFELLTKSVCPLPEKFHGLKNVETRYRQRY LDLIMNEESRETFRARSRIISLLRQFLFERDYLEFETPTLQPIYGGANARPFTTHHNALDQKLYLRIAPELYLKRLVVGG FDKVFEIAKNFRNEDIDTNHNPEFTMVEVYEAYRDYNDMMNLTEEILSHLAEKVLGTTVCSFAGHDLDFSRPWRRLTMEE AVREYAGIDFPAMSLEELHAFGLEHCVEGCESAATRGEYLVLFFEHFGEKHLIQPTFIYDFPIENSPLAKKHRSKEGLTE RFELFIAGMEMANGFSELNDPLDQKARLEQQDAKRRKGDLEAQMIDYDFINALGYGMPPTGGVGIGIDRLVMLLTGKDSI KEVLLFPQMKTAVPGQNGDKAEEGDGEE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 2e-103 | 47 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | YP_001048246.1 | lysyl-tRNA synthetase | VFG1668 | Protein | 9e-104 | 47 |
