Gene Information

Name : Memar_1349 (Memar_1349)
Accession : YP_001047261.1
Strain : Methanoculleus marisnigri JR1
Genome accession: NC_009051
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 1337260 - 1339356 bp
Length : 2097 bp
Strand : +
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: mst:Ms

DNA sequence :
ATGCTTCTGCTCGGTGAAAGGGCGACCCGTCTTTTGAGCGATCGCGCCGGCGACAGATCGGGATATGCGCCCGGACACCC
TTTAAGTGAGACGCAGTTAAGGTTGCAGGGTTATGATAGAGACCTGCGCCCGAACGACTCCGGCCGGAGGCAGGCCGTGA
CGGAGCGTGAGGAGTGCCCGTCCTGCCCCCGATGCCGGGCCGGGATCTGCGAGATTCACAGGCCGGTCGTCGGGCGCCGG
GAGATCGCGGTCTTCGGGATCTCGGGCATCCTCCTCCTTTCGGGGATACTCGTGAACTACCTCACCCCGTATCCCCTCGC
CGGCACGGCCCTGCTGCTCGCTGCCGCGGCTATATCCGGCTACGACGTCCTGAGAGCCGGATTCTTTGCTCTCATCCGGC
TCCGGTTCAGCATCGCCGTGCTCATATCCATCGCGGCGGCAGGGGCGTTCCTGACCGGAAACCCGGCCGAAGGGGCGACC
GTGCTCTACCTCTACGCCGTCGCCGAGTTCATGGAGGAGTACGCGGCCGGGAGGGCAGAGCGCTCGATAGCCTCGCTCCT
CGATCTCACGCCGCAGACCGCCCGGGTCAGGCGAGACGATGGGGAGGTGACCGTCCCGGTCGATGACGTCGGCATCGGGG
AGACCGTGATCGCGAGACCGGGCGACACCGTTCCGCTCGACGGCGTCGTCACTGCCGGCGGATCATCGGTCGATCAGGCG
GCGATCACCGGTGAGAGCGTCCCGGTGGCAAAGGGAGTCGGGGACGGCGTCTACGCCGGGACGCGGAATCTCGACGGGTA
CCTCGAGGTCCGGGTGACGAAACCGGAACGAGAGAGCACGATAGCCCGGGTCGCCGCCCTGGTCGCGGAGGCCCAGGCCC
ACACCTCTCCCACCGAGGCGTTCATCGAACGGTTTTCGCGCTACTACACGCCGGCGGTCATTCTCGGCGCCGCCCTCCTC
GTCGTGGTCCCGCCGCTCGCCTTCGGCGTCCCGTTCCTCGAGGCGTTCTACCGGGCGCTGGTCCTGCTCGTCATCGCCTG
TCCCTGTGCGCTCGCGATCTCCACCCCGGTCTCGATGGTCTCGGGGATCACGACCGCGGCGCATAATGGCGTGCTGATCA
AGGGCAGGGACTCGCTCGAGGCCGTGGGGCTCGCCCGGGTGGTCGTCTTCGACAAGACCGGGACGCTCACGGCCGGGAGG
CTCGAGGTGGACAACGTGATCGGGTTCGGGATCCCGGAGGCGGAGGTGCTCGCCGTCGCCGTGTCGCTCGAGTCCCGTTC
GGGTCACCCGATCGCGGAGGCGATCCGGCGGCGGGCGGAGGAGGAGGGCGCCGTCCTGCAGGACGTCGGGGAGTTCGTCT
CGATTGCAGGAAGAGGCGTCCGGGGACGGATCGGCGGTGCGGCCTACGTGCTCGGAAACGTTGCGCTCTTTGTCGACGGA
GATGCTCCGGCATGGCGGGCGGATTACGACCGGCTGGAGAGCGAAGGGAAGACCGTCGTCCTCGCCGGCACCGCCTCAGG
GGTGCTTGGGCTTATCGCCCTCTCGGACGTGGTAAAGAAGGATGCAAAAAAGACGGTTGCCGCTCTCCGGGCGCGAGGAA
TCCGGACGGTGATGCTCACCGGGGACAACGAGCGCGTCGGGGGGGCGGTGGCCCGCCGCATCGGGATCGACGAGTGCCAT
GCCGGGCTCCTGCCGGAGGATAAGGTGACGATGGTCGAGCGGCTGATGGACCGCTACGGGCTCGTGGTGATGGTCGGCGA
CGGCGTGAACGACGCGCCGGCGCTTGCGCGGGCGAACGTCGGGGTCGCGATGGGGGCGATAGGCTCAGACGTCGCGATCG
AGGCCGCCGACATCGTCGTGATGGAGGACGACATCTCGCGGGTCGCCTACCTCGTCGCCCTCTCGGAGAAGACGGTCTCG
GTCGTCCGGCAGAACGTCATAGCGGCGCTCGTGGTGAAACTCGGCATCGCCGGGCTCGCCGTCCTCGGGCTGGTCACGCT
CTGGATGGCGGTGGCGTTCGGGGACATGGGCCTCTCGCTTGCGGTCATCGCGAACGCTCTCAGGATAGGCCGGCCGGATT
CCGGCAGCCCTCCATGA

Protein sequence :
MLLLGERATRLLSDRAGDRSGYAPGHPLSETQLRLQGYDRDLRPNDSGRRQAVTEREECPSCPRCRAGICEIHRPVVGRR
EIAVFGISGILLLSGILVNYLTPYPLAGTALLLAAAAISGYDVLRAGFFALIRLRFSIAVLISIAAAGAFLTGNPAEGAT
VLYLYAVAEFMEEYAAGRAERSIASLLDLTPQTARVRRDDGEVTVPVDDVGIGETVIARPGDTVPLDGVVTAGGSSVDQA
AITGESVPVAKGVGDGVYAGTRNLDGYLEVRVTKPERESTIARVAALVAEAQAHTSPTEAFIERFSRYYTPAVILGAALL
VVVPPLAFGVPFLEAFYRALVLLVIACPCALAISTPVSMVSGITTAAHNGVLIKGRDSLEAVGLARVVVFDKTGTLTAGR
LEVDNVIGFGIPEAEVLAVAVSLESRSGHPIAEAIRRRAEEEGAVLQDVGEFVSIAGRGVRGRIGGAAYVLGNVALFVDG
DAPAWRADYDRLESEGKTVVLAGTASGVLGLIALSDVVKKDAKKTVAALRARGIRTVMLTGDNERVGGAVARRIGIDECH
AGLLPEDKVTMVERLMDRYGLVVMVGDGVNDAPALARANVGVAMGAIGSDVAIEAADIVVMEDDISRVAYLVALSEKTVS
VVRQNVIAALVVKLGIAGLAVLGLVTLWMAVAFGDMGLSLAVIANALRIGRPDSGSPP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 4e-86 43
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 4e-86 43
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 2e-82 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Memar_1349 YP_001047261.1 heavy metal translocating P-type ATPase BAC0298 Protein 3e-73 45
Memar_1349 YP_001047261.1 heavy metal translocating P-type ATPase BAC0092 Protein 3e-71 43