Gene Information

Name : Smar_0235 (Smar_0235)
Accession : YP_001040256.1
Strain : Staphylothermus marinus F1
Genome accession: NC_009033
Putative virulence/resistance : Unknown
Product : carbamate kinase-like carbamoyl phosphate synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0549
EC number : 2.7.2.2
Position : 248175 - 249146 bp
Length : 972 bp
Strand : +
Note : this enzyme from Pyrococcus has carbamoyl phosphate synthetase activity even though the enzyme shows sequence and structural similarity to carbamate kinase; this enzyme using carbate and ATP to synthesize carbamoyl phosphate which may be a favorable react

DNA sequence :
ATGGATAGACATGAGAAATACATAGTAGTAGCATTCGGTGGCAACGCATTCCAGACCAAGGGAGAGAAAGGCACTCCTGA
AAACTATTGGAAAAACGCTTATCGTAGCGCAGAGTTCCTGGTAAAAATAATTAATGAGGGATATAAAGTAGCTATCACAC
ATGGTAATGGTCCTCAGGTCGGCATTATTGCTGAATGGATGTTGGCCGGGAAGAAACTTAAAGGACTAGAGGTTATGACA
CTAGATATTGCTGGAGCTATGAGTCAGGGATGGCTCGGCTACTTAATACAGCAGAGCCTATATAATAAGCTCCAAGAACA
AGGATTGCTTGGTAAAGTAGTTAAAGGAGTAGTAACCATTGTTACACAAACAATAGTAGATAAAAACGACCCAGCTTTCC
AGAACCCAACAAAATATATTGGTCCATGGTATAATGAAGAGGAAGCTAAACAATTAGCAAAAGAGTTCGGTTGGACCGTT
AAACCAGATCCCCGCGGTGGCTGGAGACGAGTTGTTCCATCACCAGATCCTAAGGGTCATGTTGAAATAGAAGCTGTTAA
AAAACTTCTCGACGAAGGATTCATAGTTATAGCTAGTGGTGGTGGAGGAATACCTGTATATATAAATGATAAAGGATTAG
TTCACGGCGTTGAAGCCGTTATAGACAAGGACCTAGCAGGCGAAAGATTAGCAACAGCTATAGGTGCCGGGACATTCATG
ATTCTTACAGACGTAGACAAAGTATACTTAAACTATGGCAAACCTGATCAGAAACCAATTGATGTTATGACTGTCAGTGA
AGCAAAGAAGTTCTATGAAGAAGGACACTTTAAACCAGGCAGTATGGGACCAAAAGTTCTTGCAGCGATAAGATTTATTG
AAAACGGCGGTAAACAAGCAATCATTGGACACTTAACACAAGCATATGAAGCATTAAAAGGAAAAGCAGGTACAAGAATA
ATTCCCGACTAA

Protein sequence :
MDRHEKYIVVAFGGNAFQTKGEKGTPENYWKNAYRSAEFLVKIINEGYKVAITHGNGPQVGIIAEWMLAGKKLKGLEVMT
LDIAGAMSQGWLGYLIQQSLYNKLQEQGLLGKVVKGVVTIVTQTIVDKNDPAFQNPTKYIGPWYNEEEAKQLAKEFGWTV
KPDPRGGWRRVVPSPDPKGHVEIEAVKKLLDEGFIVIASGGGGIPVYINDKGLVHGVEAVIDKDLAGERLATAIGAGTFM
ILTDVDKVYLNYGKPDQKPIDVMTVSEAKKFYEEGHFKPGSMGPKVLAAIRFIENGGKQAIIGHLTQAYEALKGKAGTRI
IPD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0102 NP_763657.1 carbamate kinase Not tested SCCpbp4 Protein 1e-40 43
SAV1170 NP_371694.1 carbamate kinase Not tested vSa¥ã Protein 3e-40 42
SA1013 NP_374286.1 carbamate kinase Not tested vSa¥ã Protein 3e-40 42
arcC YP_493761.1 carbamate kinase Not tested vSa¥ã Protein 3e-40 42
arcC1 YP_186045.1 carbamate kinase Not tested vSa¥ã Protein 3e-40 42
MW1051 NP_645868.1 carbamate kinase Not tested vSa¥ã Protein 3e-40 42
SAKOR_01091 YP_008491279.1 Carbamate kinase Not tested vSa¥ã Protein 3e-40 42
APECO1_2636 YP_859422.2 carbamate kinase Not tested Not named Protein 1e-37 42