Gene Information

Name : fliP (Cthe_0481)
Accession : YP_001036912.1
Strain : Clostridium thermocellum ATCC 27405
Genome accession: NC_009012
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis protein FliP
Function : -
COG functional category : N : Cell motility
COG ID : COG1338
EC number : -
Position : 594275 - 595057 bp
Length : 783 bp
Strand : +
Note : FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus

DNA sequence : 
ATGAAAACTAGGCTAAAATATCTTGGGATTATTTTATTAACAATAACAGTATTTATGTTAATAACGTCAAATGTTTATGC
AGAGCCTGACTCAATAGCTTTGCCAAAACTAGGCTTTACGGTGGAACCTTCCGACAATCCCCAGGATGTTTCGACCACTA
TTCAGATAATTGTGCTTTTAACGATTCTGTCATTGGCTCCATCTATATTAATTATGATGACAAGTTTTGTCAGAATAATC
ATCGTGCTTTCCTTTTTCAGGAACGCGATTGGAACCCAACAAATGCCGCCGAATCAAGTTTTGATTGGGCTAGCTTTGTT
TTTAACCCTGTTTATCATGAGGCCTGTATTAACGGAGATAAATGAAACTGCTTTTAAGCCTTACACAAATCAGGAAATTA
CTCAGGAAGTTGCTTTGGAAAGGTCTTCGGATATTATCAAAAGGTTCATGCTAAAGCAAACATCCAAAAATGATCTCGGT
CTTTTCGTATCGCTTTCCGGCATGGAAACACCCATAAAAGAAGAAGACATTCCAAAACTTCCGTTAACCATAGTTATTCC
GGCGTTTATAATAAGTGAGCTGACAATAGCTTTTAAAATAGGTTTTTTAATATATATACCGTTTCTGGTAATTGACATGG
TGGTTTCAAGTACTCTTATGTCCATGGGTATGATGATGCTTCCTCCTGTAATGATATCTCTTCCTTTCAAGATATTGCTG
TTCATCATGGTGGGAGGATGGAATCTTATGACGCAGATGATAGTAAACAGTTTTGTTACATAG

Protein sequence : 
MKTRLKYLGIILLTITVFMLITSNVYAEPDSIALPKLGFTVEPSDNPQDVSTTIQIIVLLTILSLAPSILIMMTSFVRII
IVLSFFRNAIGTQQMPPNQVLIGLALFLTLFIMRPVLTEINETAFKPYTNQEITQEVALERSSDIIKRFMLKQTSKNDLG
LFVSLSGMETPIKEEDIPKLPLTIVIPAFIISELTIAFKIGFLIYIPFLVIDMVVSSTLMSMGMMMLPPVMISLPFKILL
FIMVGGWNLMTQMIVNSFVT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ssaR YP_216427.1 type III secretion system protein Virulence SPI-2 Protein 2e-23 43
ssaR CAA68199.1 secretion system apparatus, SsaR Virulence SPI-2 Protein 2e-23 43
ssaR NP_460384.1 type III secretion system protein Virulence SPI-2 Protein 2e-23 43
escR AFO66317.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 3e-23 43
escR AFO66400.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 3e-23 43
escR CAC81847.1 EscR protein Virulence LEE II Protein 2e-24 43
escR NP_290283.1 type III secretion system protein Virulence LEE Protein 3e-24 43
escR CAI43889.1 EscR protein Virulence LEE Protein 2e-24 43
escR AAC31528.1 L0049 Virulence LEE Protein 2e-24 43
escR ACU09473.1 type III secretion system protein EscR Virulence LEE Protein 2e-24 43
escR YP_003223490.1 T3SS structure protein EscR Virulence LEE Protein 3e-24 43
escR AAK26700.1 EscR Virulence LEE Protein 2e-24 43
escR YP_003232138.1 type III secretion system protein Virulence LEE Protein 3e-24 43
escR AAL57527.1 EscR Virulence LEE Protein 2e-24 43
escR YP_003236103.1 T3SS structure protein EscR Virulence LEE Protein 3e-24 43
yscR NP_456109.1 putative type III secretion protein Virulence SPI-2 Protein 1e-22 42
yscR NP_805090.1 type III secretion system protein Virulence SPI-2 Protein 1e-22 42
escR AAC38369.1 EscR Virulence LEE Protein 1e-23 42
hrcR NP_791222.3 type III secretion protein HrcR Virulence Hrp PAI Protein 1e-16 41
hrcR AAG33884.1 HrcR Virulence Hrp PAI Protein 1e-16 41
unnamed AAL06354.1 EscR Virulence LEE Protein 9e-25 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliP YP_001036912.1 flagellar biosynthesis protein FliP VFG2016 Protein 6e-38 55
fliP YP_001036912.1 flagellar biosynthesis protein FliP VFG1259 Protein 3e-39 55
fliP YP_001036912.1 flagellar biosynthesis protein FliP VFG2494 Protein 1e-41 53
fliP YP_001036912.1 flagellar biosynthesis protein FliP VFG2338 Protein 2e-40 50
fliP YP_001036912.1 flagellar biosynthesis protein FliP VFG0519 Protein 1e-23 43
fliP YP_001036912.1 flagellar biosynthesis protein FliP VFG0827 Protein 1e-24 43
fliP YP_001036912.1 flagellar biosynthesis protein FliP VFG0715 Protein 8e-24 42
fliP YP_001036912.1 flagellar biosynthesis protein FliP VFG0044 Protein 3e-23 41