Gene Information

Name : Cthe_2650 (Cthe_2650)
Accession : YP_001039042.1
Strain : Clostridium thermocellum ATCC 27405
Genome accession: NC_009012
Putative virulence/resistance : Virulence
Product : polysaccharide biosynthesis protein CapD
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1086
EC number : -
Position : 3131748 - 3133571 bp
Length : 1824 bp
Strand : -
Note : PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility-like; KEGG: ctc:CTC02268 CapD pro

DNA sequence :
ATGAAGAATTTGAACAACAGAATATGTCTGGCCGCCGATTGCTTGTTGGTAAACGTGGCTTTGTTTGCCGCACTTATGAT
AAAGTTTGATGCAAACATCCCGGAAAATTTGCTTAAAATAATACCTTTTAATTTTCTTATTACAACTACGGTAAGCATAT
TAGTATTTAATATATTCGGCATATATTCAATGCTATGGAACTATGCAAGTGTTGAAGAGCTTTTGAAAATATTTTGGGCA
ACAATGACATCGGTAATTGTCCAACTTCTTTTGGCTGCATATTTTAATGTGATGTTCCCTGTTTCGGTTTACATTACATG
CTGGATGATTACATTTTATTTTATAGGCGGAACAAGATTCATCGTCAGAATAACCAGGAGTATAAAAGCAAAAAAGAGAA
AAAACACCCACAAAAAAAGAATAATGATTATCGGCGCCGGTGATACCGCTTCACTGTTGATTAAGGAAACAAAAAACAAT
AAGCGCAGCATATATGAGCCGGTAGTTGCAATTGACGACGACCCTAAAAAGCACAACACCCAAATAAACGGTGTTCCCAT
CATAGGAGGCAGGGATAAAATCATAGAAGCCGCAAAGGATATGTCTATAGAAGAAATAGTTTTAGCCATGCCGTCGGTTT
CAAAAAAAGAAACGCTGGAAATTATAGACTTGTGCCAGAAGACAGGCTGCAAATTAAAAGTTTTGCCAAGCGTGTACGGC
ATTGTAAACGGAGAAGTAAGCATCAAGGAAATAAGAGACGTCACTGTCGAGGACCTTTTGCCAAGAGATGAAATTTCCCT
TTCCATAGAAGAGATATCCGGATATCTTAAAGGTGAAACCATTCTGGTTACCGGGGGAGGAGGTTCCATTGGCTCCGAGC
TTTGCAGGCAAATAGCATCTTATGAGCCTAAAACCCTCCTGGTGTTTGATATATACGAAAATAATGCTTACGAGCTTCAA
AATGAACTTGTGCAAAAATATAAAGGCAATCTGGATATCAAAGTGATAATAGGATCAATACGGGATAAAAAAAGACTGGA
TTATGTGTTTTCCCAATACAAGCCGGGCATAGTGTTTCATGCAGCGGCTCACAAGCATGTCCCGCTTATGGAGTTCAATC
CCCAGGAAGCCGTCAAGAACAATGTATTCGGCACATTAAATGTTGCCGAATGCGCCCATCAATACAACTGTAAAAAATTT
GTGCTAATCTCGACCGACAAAGCGGTAAACCCAACAAGCATAATGGGAGCAACAAAAAGAATTGCCGAGCTTATAATACA
ATATATGAACAGCATAAGCAAAACAAAATTTTGCGCCGTAAGATTCGGCAACGTACTGGACAGCAACGGAAGCGTCATCC
CCCTTTTTAAAAAGCAGATTGAACAGGGAGGCCCCATAACAATAACCCATCCCGAAGTATCCCGGTATTTTATGACCATT
CCCGAGGCGGTAAGCCTTGTCATTCAATCCGGAGCCATGATGGAAGGGGGAGAAATATTTATACTTGACATGGGCAAACC
GGTTAAAATTACCGACCTTGCCAGAACGTTAATTTCTTTGTCGGGGTTAAAGCCCGGTGTTGACATAGATATTGAATATA
TTGGATTAAGACCAGGCGAAAAGCTCCATGAAGAGCTGCTTATTTCAGAGGAAGGAGTCAGCGTAACAAAGAATGACAAA
ATATTTATTGAAAAGAGCAGAATGATTGACTTTGACAAGTACATGCAGAGAATAAAAGAGTTTGAGCTTGATAATTTGGA
TGACAGCGAAAAAGTGATAAATTTTATCAAAGAATTAGTTCCCACCTATAAGAAAAATTTGTAA

Protein sequence :
MKNLNNRICLAADCLLVNVALFAALMIKFDANIPENLLKIIPFNFLITTTVSILVFNIFGIYSMLWNYASVEELLKIFWA
TMTSVIVQLLLAAYFNVMFPVSVYITCWMITFYFIGGTRFIVRITRSIKAKKRKNTHKKRIMIIGAGDTASLLIKETKNN
KRSIYEPVVAIDDDPKKHNTQINGVPIIGGRDKIIEAAKDMSIEEIVLAMPSVSKKETLEIIDLCQKTGCKLKVLPSVYG
IVNGEVSIKEIRDVTVEDLLPRDEISLSIEEISGYLKGETILVTGGGGSIGSELCRQIASYEPKTLLVFDIYENNAYELQ
NELVQKYKGNLDIKVIIGSIRDKKRLDYVFSQYKPGIVFHAAAHKHVPLMEFNPQEAVKNNVFGTLNVAECAHQYNCKKF
VLISTDKAVNPTSIMGATKRIAELIIQYMNSISKTKFCAVRFGNVLDSNGSVIPLFKKQIEQGGPITITHPEVSRYFMTI
PEAVSLVIQSGAMMEGGEIFILDMGKPVKITDLARTLISLSGLKPGVDIDIEYIGLRPGEKLHEELLISEEGVSVTKNDK
IFIEKSRMIDFDKYMQRIKEFELDNLDDSEKVINFIKELVPTYKKNL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-99 47
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 6e-103 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cthe_2650 YP_001039042.1 polysaccharide biosynthesis protein CapD VFG1300 Protein 6e-97 44
Cthe_2650 YP_001039042.1 polysaccharide biosynthesis protein CapD VFG0029 Protein 5e-78 43