Gene Information

Name : hemC (Cthe_2527)
Accession : YP_001038922.1
Strain : Clostridium thermocellum ATCC 27405
Genome accession: NC_009012
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2995247 - 2996125 bp
Length : 879 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAAAATCAGAGTGGGCAGCCGTGAAAGCAAACTTGCTGTGAGGCAAGCGCAGATAGTGATAGATTCTATAAAAAAATA
CAACCCCGATATCGAGATCGAGCTTGTGACAATGAAAACAACAGGGGATAAAATTCTTGACAAAACCATTGACAAGATTG
GCGGGAAAGGTCTGTTTGTAAAGGAACTTGATCGTGCCTTGCTGGACGGAAAGGTGGATATCACCGTTCACAGCTTTAAG
GACATGCCCATGGATATAGATGACCGTCTACCCATTGTTGCGGTTTCAAAAAGGGAAGACCCCAGGGATGTGCTTGTATT
GCCCAAAGGGAAAAATGAAATTGATTTTAACGGTCCCATCGGCTGTTCAAGTTCAAGAAGAAAAATTCAGATAGAGAAAA
TCTATCCCGGCTGCACAGTCGAGCCGATAAGGGGAAATGTTTTAACCCGCCTTGAAAAGCTGGACAAGGGAGAATATTCA
GCCATAGCCCTGGCATATGCCGGCCTTAAGAGACTGGGACTTGAAGAGAGAATATGGCGTGTGTTCAGTACGGATGAAAT
TGTTCCGGCGGCATGTCAGGGAATTATAGCTGTACAAGCACGAAAAGATTTTGACGCATCGATTTTGGCAAATTTCCATG
ACAAAGACTCGTGGGATGTGTCGGTGGCGGAGAGAAGCTTTATAAAGGCATTGAACGGCGGATGCAGCTCTCCGTCCGCA
GCTTATGGAGTGATACAGGGCGAAAAAATAGTTCTCACGGGATTTTATGTTGATAAAAACGGCAAAATTTATAAAATGAC
CAAAACGGGAGACAGAAATCAGGGAGAAGCGTTGGGATACAGTTTGGCGATGGAAATGCTGAAGGGAGCGGATGCATAA

Protein sequence :
MKIRVGSRESKLAVRQAQIVIDSIKKYNPDIEIELVTMKTTGDKILDKTIDKIGGKGLFVKELDRALLDGKVDITVHSFK
DMPMDIDDRLPIVAVSKREDPRDVLVLPKGKNEIDFNGPIGCSSSRRKIQIEKIYPGCTVEPIRGNVLTRLEKLDKGEYS
AIALAYAGLKRLGLEERIWRVFSTDEIVPAACQGIIAVQARKDFDASILANFHDKDSWDVSVAERSFIKALNGGCSSPSA
AYGVIQGEKIVLTGFYVDKNGKIYKMTKTGDRNQGEALGYSLAMEMLKGADA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 8e-43 42
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 8e-43 42