Gene Information

Name : Cthe_2340 (Cthe_2340)
Accession : YP_001038735.1
Strain : Clostridium thermocellum ATCC 27405
Genome accession: NC_009012
Putative virulence/resistance : Virulence
Product : UDP-glucose/GDP-mannose dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 2789803 - 2791122 bp
Length : 1320 bp
Strand : -
Note : PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: ftl:FTL_0596 UDP-glucose/GDP-mannose dehydrogenase

DNA sequence :
ATGGGATTGTATGAAAAAATTGTTAATAAGGAAGAGAAAATTTCTGTGATTGGATTAGGCTACGTGGGAATGCCATTAGC
CATTGCATTTGCTAAATATGCACAGGTAATTGGATTTGATGTGGACAAAAAAAAGATTGAAATATATAAATCAGGAATCG
ATCCAACAAAAGAGATAGGGAATGAAGCTATAAAAAATACAACTGTTGAATTTACGTCCGATGAAACAAAGTTAAAAGAA
GCAAAATTTCATATAGTGGCAGTTCCCACCCCGATTAATATAGATAAAACTCCGGATTTGACACCGGTTGAAAGTGCAAG
TGTTATTGTGGGAAGAAATATGGCTAGAGGTTCATATGTGGTCTATGAATCAACAGTTTATCCTGGAGTAACTGAGGATA
TTTGTATTCCAATACTTGAAAGAGAATCGGGACTTAAATGCGGAGTTGATTTTAAAGTTGGATATTCTCCGGAACGTATT
AATCCAGGAGACAAGAAGCATACGCTGGAAACAATAAAAAAAATTGTATCTGCTATTGATGATGAAAGTTTAGATGAGAT
TGCAAAAATTTATAGCCTTGTGATAAAAGCAGGAGTGCATAAGACCAGCTCGATTAAAGTTGCCGAGGCGGCTAAAGTTG
TGGAAAACAGCCAAAGGGATATAAATATTGCCTTTATGAATGAACTTGCGATGGTATTTGATCGTATGGGCATTGATACG
AAAGAAGTTATAGATGCCATGAATACAAAGTGGAATGCACTGGGATTTTATCCTGGTTTGGTGGGTGGACATTGCATTGG
TGTGGATCCCTATTATTTTATTTATCAGGCGGAAAAGCTGGGATATCACAGTCAAATTATTCTTTCCGGAAGAAAAATTA
ATGATGGAATGGGTGAATTTATAGCTAACACCATAATTAAGAAGCTTATACATGTCAATAAAGTAGTAAAAAAATCAAAA
GTAGTTATTTTCGGTATTACTTATAAAGAAAATTGCCCGGATACAAGAAACTCCAAGGTTGTAGATATAATTAAAGGATT
GAATGAGTATGGAATAGAACCCATAGTGGTTGATCCTCAGGCAAACAGGGAAGATACAAAACAAGAATATGGCATTGAAC
TGATGGATATAGATGATGTGAAAGATGCGGACTGCCTTGTATTTGCCGTTGCCCATGATGAATTTAAAAATATGGCTTGG
GAGCAGATAGAAAAATTCTTTAAAAATATTGATAATAGCGAAAAAGTAATTATTGATGTAAAGGGAATATTTGATAAAAA
TAAAATCGAGAAACTAGGCTATTGCTACTGGAGGCTATGA

Protein sequence :
MGLYEKIVNKEEKISVIGLGYVGMPLAIAFAKYAQVIGFDVDKKKIEIYKSGIDPTKEIGNEAIKNTTVEFTSDETKLKE
AKFHIVAVPTPINIDKTPDLTPVESASVIVGRNMARGSYVVYESTVYPGVTEDICIPILERESGLKCGVDFKVGYSPERI
NPGDKKHTLETIKKIVSAIDDESLDEIAKIYSLVIKAGVHKTSSIKVAEAAKVVENSQRDINIAFMNELAMVFDRMGIDT
KEVIDAMNTKWNALGFYPGLVGGHCIGVDPYYFIYQAEKLGYHSQIILSGRKINDGMGEFIANTIIKKLIHVNKVVKKSK
VVIFGITYKENCPDTRNSKVVDIIKGLNEYGIEPIVVDPQANREDTKQEYGIELMDIDDVKDADCLVFAVAHDEFKNMAW
EQIEKFFKNIDNSEKVIIDVKGIFDKNKIEKLGYCYWRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 8e-92 51
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 8e-92 51
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 1e-102 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cthe_2340 YP_001038735.1 UDP-glucose/GDP-mannose dehydrogenase VFG0431 Protein 3e-92 51