Gene Information

Name : Cthe_2334 (Cthe_2334)
Accession : YP_001038729.1
Strain : Clostridium thermocellum ATCC 27405
Genome accession: NC_009012
Putative virulence/resistance : Virulence
Product : polysaccharide biosynthesis protein CapD
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1086
EC number : -
Position : 2781498 - 2783342 bp
Length : 1845 bp
Strand : -
Note : PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; CoA-binding; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility-like; KEGG: tte:TTE0

DNA sequence :
ATGAAACAAAAGATTAGAGCAAATGGATTAATTGCAATTGATGTGTTTTTAGTAAATATATCGCTTGTTATTGCATATCT
TTTGAGGTTTGACTTAAACTATGCAAATATTCCGGAACGTTTTATCGAACCCTTGGTAAAGCTCGCCGTAATTTCAACAG
TTGTTAAACTTATAACTTATGCTGTGATGAAGCTTTACAACAGTTTGTGGAAGTATGCGGGAATATATGAAGTGGTTATG
GTTATAGCTGCTTCATTTATCAGCAATTCAATAATGATAAGCTATGTGTTTTTATCCCAAACGCCCGTACCTCGAAGTAT
ATTCCTGATATGCATCTTGACGGATATTGCCCTGATTGGGGGAGTACGGTTTGCTTACAGGGTGTTTAGAAGAATTGTCA
AAGGGGAAATGATTCGTTTTACAAATTCAAAGAGGGTGCTGATTGCAGGCGCCGGGGACGCCGGCGCGATAATTGTGAAG
GAAATGAAGTCCCATCCTAAACTTAAAAGCACTCCGGTGGCGTTTGTAGATGACGATAAATACAAAATAGGCAAAAAAAT
CAGCGGAGTGCCTGTGGTGGGTGAGACAAAGGATGTTTCAGAAATAATACAGAAGCTGCAGATAGACGAAGTCATTATTG
CCATGCCGTCTGCCAGCCACAAAAAAATAAATGATATATACACCGGCTGTGCCCAAACAAACTGCAAGGTAAAGATACTT
CCGTCGGTTTCACAGCTGATTGATGAATCTGTTGTCATGCAGAAAATAAGGGATGTGAATATAGAAGACCTTTTGGGAAG
GGAACCTGTACATCTTGATATTGAAGAGATAGGTTCGTATCTGAAGGACCGGGTGGTAATGGTTACCGGGGGAGGAGGCT
CAATCGGTTCGGAGCTGTGCAGGCAGATAGCGAATTTTTTGCCGAAGAGGCTTGTTATTTTGGATAATTATGAAAACAAT
GCATATGACATACAGAATGAACTTTTGTACAAGCATCCGGATTTAAAGCTTGACACAGTGATTGCCAATATCAGAGAAAA
ACAGAGAATGGAAAACATATTTAAAAAATACAGGCCAGACGTTGTATTTCATGCTGCGGCCCATAAACATGTCCCTCTTA
TGGAGGACAATCCTACGGAGGCGATAAAAAATAATGTGTTTGGCACCTTAAATGTGGCTGAATGTGCGGACAAGTATGGA
ACTAAAAGGTTTGTACTTATATCCACGGACAAGGCCGTCAACCCTACGAATATTATGGGTGCGACAAAAAGAATTGCAGA
AATGATTATCCAGGCGATGAATGAAAACAGCAAAACCGAGTTTGTTGCGGTAAGGTTTGGAAACGTGCTTGGAAGCAACG
GAAGTGTTGTACCACTGTTTAAAAAGCAGATAGAAAGGGGAGGACCGGTAACGGTCACCCATCCGGAAATCACCAGATTC
TTTATGACAATTCCGGAGGCTGTGCAGCTGGTACTACAAGCTGGGGCAATGGCAAAGGGCGGAGAAATATTTGTTCTTGA
TATGGGTGAACCTGTGAAAATAAGTGAGCTTGCCCGAAACTTGATAAGACTTTCGGGTTTTGAGCCGGATGTCGATATAA
AGATTGAGTATATAGGTTTGAGACCCGGCGAAAAGCTTTATGAGGAACTTATGCTCAGTGAGGAAGGGCTTTTGGCAACC
AAAAACGACAAAATATATGTTACAAAGCCTGTTCATATTGATTTTAAGGTGCTCCAGAGGGAGCTGGATTGCCTTAAGGA
TATTATGGTTACAAATTCTGAAGAGATTTCAGAATATATTAAACTTATTGTGCCTACGTACAAGAAAGCGGGAAACGGAA
ATTAA

Protein sequence :
MKQKIRANGLIAIDVFLVNISLVIAYLLRFDLNYANIPERFIEPLVKLAVISTVVKLITYAVMKLYNSLWKYAGIYEVVM
VIAASFISNSIMISYVFLSQTPVPRSIFLICILTDIALIGGVRFAYRVFRRIVKGEMIRFTNSKRVLIAGAGDAGAIIVK
EMKSHPKLKSTPVAFVDDDKYKIGKKISGVPVVGETKDVSEIIQKLQIDEVIIAMPSASHKKINDIYTGCAQTNCKVKIL
PSVSQLIDESVVMQKIRDVNIEDLLGREPVHLDIEEIGSYLKDRVVMVTGGGGSIGSELCRQIANFLPKRLVILDNYENN
AYDIQNELLYKHPDLKLDTVIANIREKQRMENIFKKYRPDVVFHAAAHKHVPLMEDNPTEAIKNNVFGTLNVAECADKYG
TKRFVLISTDKAVNPTNIMGATKRIAEMIIQAMNENSKTEFVAVRFGNVLGSNGSVVPLFKKQIERGGPVTVTHPEITRF
FMTIPEAVQLVLQAGAMAKGGEIFVLDMGEPVKISELARNLIRLSGFEPDVDIKIEYIGLRPGEKLYEELMLSEEGLLAT
KNDKIYVTKPVHIDFKVLQRELDCLKDIMVTNSEEISEYIKLIVPTYKKAGNGN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 2e-107 49
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 2e-99 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cthe_2334 YP_001038729.1 polysaccharide biosynthesis protein CapD VFG1300 Protein 3e-103 44
Cthe_2334 YP_001038729.1 polysaccharide biosynthesis protein CapD VFG0029 Protein 3e-84 43