Gene Information

Name : Cthe_2256 (Cthe_2256)
Accession : YP_001038651.1
Strain : Clostridium thermocellum ATCC 27405
Genome accession: NC_009012
Putative virulence/resistance : Unknown
Product : primary replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : 3.6.1.-
Position : 2684571 - 2685908 bp
Length : 1338 bp
Strand : -
Note : TIGRFAM: replicative DNA helicase; PFAM: DnaB-like helicase-like; KEGG: tte:TTE2774 replicative DNA helicase

DNA sequence :
ATGGACTTGGGTTCTTTTGGCCGGATACCCCCGCAAAATATTGAGGCTGAGCAGTCGGTACTGGGTGCCATACTGCTGGA
CAAAGAAGTTCTGTCAAGTGTAACGGAGATAATTTCAAGCCAGGACTTTTACAGAGAGGACCATAGGGAAATATTCGAAG
CAATAATGGACCTTTATGAAAAGGGAGAACCTATTGACCTCATTACAGTTGCGGAACAGCTTAAGGTAAGAGGGAGTCTG
GAGGCGGTAGGTGGGCTTGAGTATCTTACGAATCTGGCAAGTTTGGTTCCTACCACTGCAAATGCAAAACATTATGCAAA
AATAGTCGAAGAAAAATCTATATTAAGAAGGCTTATCAAGGCTTCCAGTGAAATAATCAATATGGGTTATGAAGCCGCGG
AAGAGGTTTCCTATGTTTTGGACAAGGCTGAAAAAAGCATATTTGACGTACTTCAGAAGAGAAACACCCAGGGGTTTGCC
CTGATTAAAGATGTATTGATTGATACTTTCAACCGGCTTGAGGAGCTTTACAACAATAAAGGATACATCACAGGAATTCC
CACCGGATTTGTGGATTTGGACTACAAGACTGCAGGGCTTCAAAATTCGGACTTGATATTGATTGCGGCAAGACCGGCCA
TGGGGAAGACTTCTTTTGTACTGAACATAGCTCAATATGCTGCCATTCACGCAAAGGTGCCTGTCGCCATATTCAGTCTG
GAAATGTCGAAAGAACAGTTGGTAAACAGAATGCTATGCTGTGAAGCCATGGTGGACAGTCAGAAGATGAGAACCGGAAA
GCTGGAGGACAGTGACTGGCAGAAAGTAGCAAGAGCATTGGGGCCTTTGTCCGAAGCGCCGATTTATATTGATGACACCC
CTGGACTTTCTGTCGCGGAAATAAGGGCAAAATGCAGAAGACTCAAGCTGGAAAAAAATTTGGGTCTGGTTGTCATAGAT
TACCTTCAGCTTATGCAGGGAAGGGGAAAAAGTGAGAGCAGGCAGCAGGAAATATCGGAGATATCTAGGTCTCTTAAGAT
ACTGGCAAAGGAGATAAACGTACCTGTGCTGACTTTGTCCCAGCTTAGCCGTGCCCCGGAGTTAAGGTCGGATCACAGGC
CTATTTTAAGCGACCTGAGGGAATCCGGCGCAATAGAGCAGGATGCGGATATAGTAATGTTCTTATACAGGGATGACTAT
TACAATCCCGATACTGAAAAGAAGAATATTGCCGAAGTGATAATTGCAAAGCACAGAAACGGTTCGACGGGTACTGTGGA
ACTGGCATGGCTGGGTCAGTATACGAAGTTTGCGAACCTTGAGAAATATAGACAATAG

Protein sequence :
MDLGSFGRIPPQNIEAEQSVLGAILLDKEVLSSVTEIISSQDFYREDHREIFEAIMDLYEKGEPIDLITVAEQLKVRGSL
EAVGGLEYLTNLASLVPTTANAKHYAKIVEEKSILRRLIKASSEIINMGYEAAEEVSYVLDKAEKSIFDVLQKRNTQGFA
LIKDVLIDTFNRLEELYNNKGYITGIPTGFVDLDYKTAGLQNSDLILIAARPAMGKTSFVLNIAQYAAIHAKVPVAIFSL
EMSKEQLVNRMLCCEAMVDSQKMRTGKLEDSDWQKVARALGPLSEAPIYIDDTPGLSVAEIRAKCRRLKLEKNLGLVVID
YLQLMQGRGKSESRQQEISEISRSLKILAKEINVPVLTLSQLSRAPELRSDHRPILSDLRESGAIEQDADIVMFLYRDDY
YNPDTEKKNIAEVIIAKHRNGSTGTVELAWLGQYTKFANLEKYRQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 1e-71 43
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 1e-69 42
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 3e-70 42
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 5e-65 41
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 5e-65 41