Gene Information

Name : Cthe_1789 (Cthe_1789)
Accession : YP_001038203.1
Strain : Clostridium thermocellum ATCC 27405
Genome accession: NC_009012
Putative virulence/resistance : Virulence
Product : ATPase AAA-2
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2111364 - 2113820 bp
Length : 2457 bp
Strand : -
Note : PFAM: UvrB/UvrC protein; AAA ATPase, central region; Clp, N terminal; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2; SMART: ATPase; KEGG: tte:TTE2327 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGTACGGACGTTTTACCGAAAAAGCACAAAAAGCAATAAATATTTCTCAAAACATGGCAATAGAATTGGGACATAATTA
TGTCGGGACGGAGCACCTTCTTCTGGGATTGGTAAAAGAAGGAAGTGGAGTCGCCGCGCGGGTTTTGCAAAGCCAGGGCG
TTACTGAAGAGAAAGTTATAAGGGAAATTGAAGAACTCATCGGACGCGGCGAAATGATGGGCCAGCCTTTGGATTTCACT
CCGAGAACCAAAAGGGTTCTGGAGCTTAGCTATAGAGAGGCCCGCAGAATGGGTCACAACTATATCGGAACGGAGCACCT
TCTTTTAGGAATAATGAAAGAAGGGGAAAGCGTTGCCGTAAGAATTTTGAAGGACTTGGGAGTCGAGCATCAAAAGCTTG
TTCAGGAAATAATGAACATGCTCAGTGAAGAAGCACCCAATTCCACCGGTGTGCCAAAAGGCCATTCATCATATTCGAAC
ACACCGACCCTGAACCAGTTCGGAAGAGACTTGACGGAGATGGCAAGGGAGGCAAAATTTGACCCGGTAATAGGCCGTGA
CAAGGAAATTGAAAGAGTTATACAGATTTTGAGCAGAAGAACCAAAAACAACCCTTGTCTGATTGGTGAGCCCGGAGTCG
GTAAGACTGCGATTGCAGAAGGGCTTGCCCAGAAGATAGTTGAGGGAAATATTCCGGAAATATTGAAGGACAAAAGAGTT
GTGACTTTGGACTTGTCCTCAATGGTTGCCGGTGCAAAATACAGAGGTGAATTTGAAGAAAGGCTTAAAAAAGCTCTTGA
TGAAATCAGAAGGGCGGGCAATGTAATACTGTTCATAGATGAAATGCATACTATCATCGGAGCCGGAGCCGCTGAAGGTG
CAATCGACGCTTCCAATATATTAAAGCCTTCTTTGGCGCGGGGCGAAATTCAGGTTATCGGTGCCACCACCATTGATGAG
TACAGGAAGCACATTGAAAAGGACGCGGCTTTGGAGAGAAGATTCCAGCCGATACTTGTCGGAGAGCCGACAAAAGAAGA
AGCAATAGAAATATTGAGGGGTCTGAGAGACAAGTATGAAGCACATCATAGTGTGAAAATCACTGATGAGGCTTTGGTGG
CAGCCGTAAACATGTCGGACAGATACATTACGGACCGGTTCCTGCCCGATAAAGCCATCGACCTTATTGATGAGGCGGCA
TCAAGGGTAAGGCTGAAATCCTTTACCGCACCTCCTGATCTGAAACATCTCGAGGAAAAAGTGGAAAGACTCAGAAAAGA
AAAAGAAGATGCTATAGTATGCCAGGAATTTGAAAAGGCCGCCCGTATAAGAGATGAGGAGCAGAGGCTGAAAAATGAGC
TGGAAAAGGCAAAGGACAGTTGGCGGCAGAAAAATCAGACCACAACAAACGTAGTCAGTGAAGATGATATTGCAGTAATA
GTGTCCGACTGGACGGGTATTCCGGTAAAGAGACTTGCCGAGGAAGAATCGGAAAGACTTATGAAGATGGAAGACATACT
TCACAAAAGGGTAATAGGGCAGGATGAAGCGGTAAAGGCAATATCCAAAGCCATCAGAAGAGGAAGAGTGGGTCTTAAAG
ACCCGAAGAGGCCGGTGGGTTCATTCATTTTCCTGGGTCCTACAGGCGTTGGAAAAACTGAACTTAGCAAGGCTTTGGCA
GAAGCTCTCTTTGGTGAGGAAAACGCAATGATTAGAATAGACATGTCGGAGTACATGGAAAAGCACAGCGTTTCAAGACT
TGTAGGTTCACCGCCGGGATATGTAGGTTATGAAGAAGGAGGACAGCTTACCGAAAAAGTAAGAAGAAAGCCTTATTCGG
TAGTGTTGTTTGACGAAATTGAAAAGGCACATCCGGACATATTCAATATTCTGCTTCAAATTCTTGAAGACGGAAGACTG
ACGGATTCCCAGGGCAGGGTGGTGGACTTTAGAAACACGGTAATTATCATGACATCAAACATTGGTGCAAGGCTTATAAC
CGAGCCAAAGCAGCTGGGATTTGCTCCGGTCGCCCAGGATAAAAAGAAGAGCTATGAAGACATGAAGAACAACGTTATGA
ATGAGCTCAAAAAGAACTTCAGACCCGAGTTCTTAAACAGAATAGATGAAATAATCGTGTTCCATCCTCTTGAGGAAGAA
CACTTAAAGCAGATAGTAGGACTTATGATAGACAATCTTGCGGAAAGACTTAAACAGAATTCAATTGAAATTGAGGTGTC
GGACGAAGCAAAAGCTCTTCTTGCAAAGAAAGGATTTGATCCTGTGTACGGAGCAAGGCCGTTAAGAAGGGCTGTACAGA
GCATGGTTGAGGACAGACTTGCGGAGGAAATGCTGGAAGGCAGAGTAAAGTCGGGAGACAAGGTATTTGTCGACGTTAAA
GATGATGAACTGGTATTTGTCAAAGACAAAAGCGAGCTTGTTTCAAACAAGGGCTAA

Protein sequence :
MYGRFTEKAQKAINISQNMAIELGHNYVGTEHLLLGLVKEGSGVAARVLQSQGVTEEKVIREIEELIGRGEMMGQPLDFT
PRTKRVLELSYREARRMGHNYIGTEHLLLGIMKEGESVAVRILKDLGVEHQKLVQEIMNMLSEEAPNSTGVPKGHSSYSN
TPTLNQFGRDLTEMAREAKFDPVIGRDKEIERVIQILSRRTKNNPCLIGEPGVGKTAIAEGLAQKIVEGNIPEILKDKRV
VTLDLSSMVAGAKYRGEFEERLKKALDEIRRAGNVILFIDEMHTIIGAGAAEGAIDASNILKPSLARGEIQVIGATTIDE
YRKHIEKDAALERRFQPILVGEPTKEEAIEILRGLRDKYEAHHSVKITDEALVAAVNMSDRYITDRFLPDKAIDLIDEAA
SRVRLKSFTAPPDLKHLEEKVERLRKEKEDAIVCQEFEKAARIRDEEQRLKNELEKAKDSWRQKNQTTTNVVSEDDIAVI
VSDWTGIPVKRLAEEESERLMKMEDILHKRVIGQDEAVKAISKAIRRGRVGLKDPKRPVGSFIFLGPTGVGKTELSKALA
EALFGEENAMIRIDMSEYMEKHSVSRLVGSPPGYVGYEEGGQLTEKVRRKPYSVVLFDEIEKAHPDIFNILLQILEDGRL
TDSQGRVVDFRNTVIIMTSNIGARLITEPKQLGFAPVAQDKKKSYEDMKNNVMNELKKNFRPEFLNRIDEIIVFHPLEEE
HLKQIVGLMIDNLAERLKQNSIEIEVSDEAKALLAKKGFDPVYGARPLRRAVQSMVEDRLAEEMLEGRVKSGDKVFVDVK
DDELVFVKDKSELVSNKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cthe_1789 YP_001038203.1 ATPase AAA-2 VFG0079 Protein 0.0 64
Cthe_1789 YP_001038203.1 ATPase AAA-2 VFG0080 Protein 5e-160 53