Gene Information

Name : Cthe_1278 (Cthe_1278)
Accession : YP_001037703.1
Strain : Clostridium thermocellum ATCC 27405
Genome accession: NC_009012
Putative virulence/resistance : Resistance
Product : ATP-dependent DNA helicase RecG
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG1200
EC number : 3.6.1.-
Position : 1553386 - 1555470 bp
Length : 2085 bp
Strand : -
Note : catalyzes branch migration in Holliday junction intermediates

DNA sequence :
ATGAACGGCGATATGAAAGAAATTCTGAAAAAATCAATAAAGAATGTTAAAGGTGTGGGAGATGCAAGAGCAAAACTGTT
TCACAAACTTGGCATTTTTAGCATAGAAGATTTGATAACCCATTTTCCCTATGACTACGAAGACAGAAGCAATATTAAAA
AAATATGTCAGCTTACCGAGGGAGAGAGCTGTACCTTTGAGGGCATTATTATGTCAAAGGTCACGGAAAGAAAAATAAGG
CAGGGATTGACTCTGTATCAGGCATATATAAAAGACGATACGGGAACCATAATAGCGACGTGGTACAATCAGCCTTATAT
TAAAAAAGTCCTGACCGTCGGTGAAAGCTATATTTTTTACGGCAAAATTGTACGGGGATACAAAACCCTGGAGGTGCAAA
ATCCGGTTTATGAGAAAGCCTGCAAGGAAGAACATAAAAATACAATGAAAATTGTGCCCGTTTACCATGCAACGGCGAAT
CTTACACAAAACACCATCAGAACCGTAATGCAAAATGCCCTGGAACTTGTTGACGGAAATTTGGAAGATGTATTGCCTTT
ATGGGTGAGAAAAAAGTATTGCCTGTGCGATATAAATTATGCTTTTTCCAATATTCATTTTCCACGAAATGACGGGGATA
TAAAAAATGCCAGGTACAGGCTGGTGTTTGAAGAGCTTTTTCTCTTGCAGCTTGGACTTCTTAGCGTCAAGACTGTACTT
TCCGACGGAAAAGAAGGTATTGCTTTTGCGCCAAACCGAAAAGAGATGGTTGACTTTATAAACAGCATAGGCTTTACGCT
TACCAATGCCCAGAAGAGGGTGTGGGAAGAGATAGAAAAGGATATGGAAAGCAACCGTGTAATGAACAGGCTTGTGCAGG
GGGATGTGGGCTCCGGCAAGACGATTGTTGCGGCTCTGGCGCTGGCTAAAGCGGTAAAGAGCGGATATCAGGGGGCAATG
ATGGTTCCTACGGAGATTCTTGCAAAGCAGCACTATGAATCGTTAAAGGATATTATGGGAAAGCACGGGATAAATGTTGC
CTTGCTGGTGGGAAGCCAGACAAAGAAGCAAAGGAGTGAAATTCTTTCAAAAATTGAATCCGGCGAGGTTAATATAGTTA
TAGGCACCCATGCACTTATTGAGGAAAAGGTCAAGTTTTCAAAGCTTGGGCTGGTTATAACCGATGAGCAGCACCGTTTT
GGGGTAAGACAAAGGGCTATGCTTTCCAACAAGGGAATAAACCCGGATATTCTTGTAATGACTGCCACACCCATTCCCAG
AACTCTTGCGCTAATCCTTTACGGGGATTTGGACATATCGATAATTGACGAACTTCCGCCGGGAAGAAAGCCTGTGAAAA
CCTATGCGGTTGACAACAGCATGAGGCAGAGAATAAACAATTTTATAAAAAAACAGATACTTGAGGGAAGACAGGCTTAT
ATAATATGTCCTCTGGTGGATGAATCGGATGAAATAGAGGCAAAATCAGCTCTAAAAACTGCGGAAAAGATAGCGAAAGA
AGATTTTAAAGATTTTAGAGTCGGTTTGCTGCATGGAAAGATGCCTGCCGGCGAAAAAGAAGAGGTCATGCAGAAGTTTT
TAAAAGGCGAAATTGACATTCTTGTGTCCACTACAGTTGTAGAGGTCGGAGTGAATGTTCCCAATGCAACACTGATGGTT
GTTGAAAATGCCGAAAGGTTTGGACTTGCCCAGCTTCATCAATTGAGAGGCCGGGTGGGAAGAGGGCCGCACCAGTCCTA
CTGCATTCTTTATAATGAGAGCAAAAGCCAGATTGCAAAAGAGAGAATGAAGGTCATGCAGGAGACCACAGACGGTTTTG
TCATATCGGAAAAAGACCTTCTGATAAGGGGGCCCGGAGAATTTTTCGGAACAAGGCAGCATGGACTGCCCGATCTTAAA
ATTGCAAATCTTTACAGAGATATGGAAATATTAAAAAAAGCGCAGGAAGCGGCGCAGGAAATTTTAAAAAGAGATCGAAA
CTTATTTATGGAAGAAAATCTAAAGTTAAAGGAAAAAATTGCCGAGAAATTCATAGAAAAAATACATGACGTAAGTTTGA
ATTAA

Protein sequence :
MNGDMKEILKKSIKNVKGVGDARAKLFHKLGIFSIEDLITHFPYDYEDRSNIKKICQLTEGESCTFEGIIMSKVTERKIR
QGLTLYQAYIKDDTGTIIATWYNQPYIKKVLTVGESYIFYGKIVRGYKTLEVQNPVYEKACKEEHKNTMKIVPVYHATAN
LTQNTIRTVMQNALELVDGNLEDVLPLWVRKKYCLCDINYAFSNIHFPRNDGDIKNARYRLVFEELFLLQLGLLSVKTVL
SDGKEGIAFAPNRKEMVDFINSIGFTLTNAQKRVWEEIEKDMESNRVMNRLVQGDVGSGKTIVAALALAKAVKSGYQGAM
MVPTEILAKQHYESLKDIMGKHGINVALLVGSQTKKQRSEILSKIESGEVNIVIGTHALIEEKVKFSKLGLVITDEQHRF
GVRQRAMLSNKGINPDILVMTATPIPRTLALILYGDLDISIIDELPPGRKPVKTYAVDNSMRQRINNFIKKQILEGRQAY
IICPLVDESDEIEAKSALKTAEKIAKEDFKDFRVGLLHGKMPAGEKEEVMQKFLKGEIDILVSTTVVEVGVNVPNATLMV
VENAERFGLAQLHQLRGRVGRGPHQSYCILYNESKSQIAKERMKVMQETTDGFVISEKDLLIRGPGEFFGTRQHGLPDLK
IANLYRDMEILKKAQEAAQEILKRDRNLFMEENLKLKEKIAEKFIEKIHDVSLN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
recG CAJ77039.1 ATP-dependent DNA helicase Not tested AbaR1 Protein 3e-83 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Cthe_1278 YP_001037703.1 ATP-dependent DNA helicase RecG BAC0356 Protein 4e-98 42