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Name : leuS (Cthe_1237) Accession : YP_001037662.1 Strain : Clostridium thermocellum ATCC 27405 Genome accession: NC_009012 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 1500066 - 1502543 bp Length : 2478 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGTATTACAATTTTGTGGATATTGAAAAGAAGTGGCAAAAGAAATGGCTGGAGGAAAAAGCTTTTGCCGTCCGGGAAGA CGAAAGCAAAAAGAAATATTATGTGCTTGAAATGTTTCCTTATCCTTCCGGAAATCTTCACATGGGACATGTGAGGAATT ATTCCATAGGAGATGTTGTGGCAAGATTTAAAAGAATGAATGGTTTTAATGTTCTTCACCCGATGGGATGGGATGCTTTC GGTTTGCCTGCCGAAAATGCTGCCATAAAAAGAGGGGTTCATCCCAATGACTGGACATGGTCCAATATCGACAACATGAG AAGGCAGTTAAAACAACTTGGCATCAGTTATGATTGGGACAGAGAGGTTGCCACCTGTCATCCCGATTACTACAAGTGGA CTCAATGGATGTTCCTTCAACTTTATAAAAACGGTCTTGCGTACAAGAAAAAGGCCTATGTAAACTGGTGCCCATCCTGT GCGACGGTTCTTGCCAACGAGCAGGTTGTAAACGGAGTTTGTGAGCGCTGCAAGTCGGTAGTCGGAAAAAAAGATTTGGA ACAGTGGTTCTTTAAGATAACCGACTATGCTCAAAGGCTTCTGGATGATATTGAAAAGCTCAAAGGATGGCCTGACAAGG TTAAAGTTATGCAGCAAAACTGGATTGGACGGAGCGAAGGTGTCGAAGTGGATTTTAAAGTGGACGGAATGGACAAAGCC GTCAGGGTATATACCACAAGACCTGATACCATATATGGCGTGACCTACGTGGTGATTGCTCCCGAGCATCCTGTGGTGAA AGAATTGATTAAGGGAACGGAACAGGAACAGGTATGTAACGAGTTTATAAACAAGATGATGTTTTTGAATGAAATAGACA GAACTGCAACCGATGTTGAGAAAGAAGGAGTTTTCACAGGAAGGTATGTCATTAATCCGTTAAACGGAGACAGAGTTCCG TTGTACCTTGCCAATTATGTTCTTGCAGAGTATGGAACCGGTGTTGTCATGGCTGTTCCTGCTCATGACCAGAGAGACTT TGAGTTTGCAAAGAAGTATAATTTGCCGATTAAAGTTGTAATTCAGCCGGAAGGCCAGGAGCTTGATGCGTCCAGGATGA CGGAAGCCTTCGTTGAGGTGGGTTATCTTGTCAATTCCGCAGAATTTGACGGTGTAAGAAGCGATGAGGCTATAGGAAAG ATAATTGATTATATCGAGCAAAAAGGCTATGGAAAAAGAAAGATAAATTACAGGCTCAGAGACTGGCTGATTTCCAGACA GAGATACTGGGGTGCGCCCATACCGATAATCTACTGTGATGATTGTGGAGCTGTGCCTGTTCCGGAAGAGGATTTGCCGG TTATTTTGCCGACGGACATCAAATTTTCCGGTGTGGGAGAGTCGCCGCTTTCGACAAGTGAGACATTCATATCAGCCCCT TGTCCTAAATGCGGTAAGATGGGAAGAAGAGAATTGGATACCATGGATACCTTTGTATGTTCTTCATGGTATTATCTTAG ATATTGTGACCCATGTAACGACAAGGCTCCTTTTGACAAGGAAAGGATAAGATACTGGTTGCCGGTTGACCAGTATATAG GCGGTGTTGAACATGCAATTCTGCACCTGTTGTATTCCAGATTCCTTATGAAGGTTCTCTATGATTTGGGATATGTGGAT TATGACGAACCGTTTACAAACCTCCTTACTCAGGGAATGGTGCTGAAAGACGGAGCCAAAATGTCAAAATCCCTGGGGAA TGTTGTAAGTCCTGAAGAGATAATTGAAAAATACGGTGCCGATACGGCAAGGTTGTTCATACTGTTTGCATCTCCACCGG AAAAAGACCTTGAATGGAGTGACCAGGGAGTTGAAGGCTGCTATAGGTTTATCAACAGAGTATGGAGAATAGTCAATGAG TTTGCCGATGCGGTAAAGGAAGGCGGAAATATTGACACTTCCACATTTACCAAGGCTGATAAAGAGCTGTGGTACATGCT GAACAACACATTGAAGCGCGTTACGGATGATATCAGCCAGAGGTTCAACTTCAACACTGCAATCAGTGCGGTTATGGAGC TGGTTAATTCCTTGTATTATTACAAGGATAAAGTGGCTGATGACAGCAAGAACAAGGCTCTTGTCAGGGAAGTAATTGAA AAGTTGATAATAATGCTGGCTCCCTTTATTCCTCATGCAACAGAAGAGCTTTGGTCCGCCATAGGAAAGGAAGGCAGCGT GCACGAACAGAAGTGGCCTTCATTTGACCCGGCTGCTCTTGTGAAGGATGAAATTGAAATAGTGGTTCAGATAAACGGAA AGGTGAGAGACAAGATTGTTGTACCGTCGGATCTTACAAAAGAGCAGGTTGAGGAGCGGGCTTTGAATAGTGAAAAGATT AAAGCTGAAACGGCCGGGAAAAATGTTGTAAAGGTTATTTCCGTTCCGGGCAAGCTGGTGAATATTGTTGTGAAATAA Protein sequence : MYYNFVDIEKKWQKKWLEEKAFAVREDESKKKYYVLEMFPYPSGNLHMGHVRNYSIGDVVARFKRMNGFNVLHPMGWDAF GLPAENAAIKRGVHPNDWTWSNIDNMRRQLKQLGISYDWDREVATCHPDYYKWTQWMFLQLYKNGLAYKKKAYVNWCPSC ATVLANEQVVNGVCERCKSVVGKKDLEQWFFKITDYAQRLLDDIEKLKGWPDKVKVMQQNWIGRSEGVEVDFKVDGMDKA VRVYTTRPDTIYGVTYVVIAPEHPVVKELIKGTEQEQVCNEFINKMMFLNEIDRTATDVEKEGVFTGRYVINPLNGDRVP LYLANYVLAEYGTGVVMAVPAHDQRDFEFAKKYNLPIKVVIQPEGQELDASRMTEAFVEVGYLVNSAEFDGVRSDEAIGK IIDYIEQKGYGKRKINYRLRDWLISRQRYWGAPIPIIYCDDCGAVPVPEEDLPVILPTDIKFSGVGESPLSTSETFISAP CPKCGKMGRRELDTMDTFVCSSWYYLRYCDPCNDKAPFDKERIRYWLPVDQYIGGVEHAILHLLYSRFLMKVLYDLGYVD YDEPFTNLLTQGMVLKDGAKMSKSLGNVVSPEEIIEKYGADTARLFILFASPPEKDLEWSDQGVEGCYRFINRVWRIVNE FADAVKEGGNIDTSTFTKADKELWYMLNNTLKRVTDDISQRFNFNTAISAVMELVNSLYYYKDKVADDSKNKALVREVIE KLIIMLAPFIPHATEELWSAIGKEGSVHEQKWPSFDPAALVKDEIEIVVQINGKVRDKIVVPSDLTKEQVEERALNSEKI KAETAGKNVVKVISVPGKLVNIVVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 4e-177 | 46 |
