Gene Information

Name : secA2 (SSA_0836)
Accession : YP_001034814.1
Strain : Streptococcus sanguinis SK36
Genome accession: NC_009009
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 821648 - 824029 bp
Length : 2382 bp
Strand : +
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGATTAAAAATCATTTTCAAATTCAGCGCTTAAAGAAAATCTTAGCCAAAGTCAAGAGCTTTGAGTCAGAAATGGCTGG
TCTGACAGACGCTGAGCTGCGGAAGAAAACTCAGGAATTTAAGGAGAGACTGGCCGCAGGTGAGACTTTAGACGACTTGC
TGCCGGAGGCTTATGCTGTGGTGCGGGAAGCGGACAAGCGGGTGCTGGGCATGTTTCCCTACGATGTTCAGGTTATGGGG
GCGATTGTTCTCCATGAAGGAAATGTCGCTGAGATGGCTACGGGAGAGGGCAAGACTCTGACGGCTACCATGCCGCTCTA
TCTCAATGCCCTGTCTGGTCAAGGAGCTATGCTGGTGACCACCAATACCTATCTGGCTCTGAGGGACGCTCAGGAAATGG
GGCAGGTCTATCGTTTTCTGGGGTTGACTATTGAGGCAGCGGTGGTAGCTGATGAGACTGAAAATTTGACGCCCAAGCAG
AAGCGGCTGATTTATCAGGCGGATATTGTCTATACGACCAATAGTGCCTTGGGCTTTGACTATTTGATTGAGAATCTCGC
AGAGAATAAGGATAGCCAATATCTTAGTCCTTTCAACTATGTCATCATAGACGAGATTGACTCCATTCTCTTGGATAGCG
CTCAGGTACCTTTGGTTATCTCTGGTGCTCCTCGGGTTCAGTCAAACTTCTATAGTATCATGGATACCTTCATTACGACT
TTGAAAGAAGAAGAGGACTACCACTACGATGACGAGAAAAATGAAGTCTGGCTGACATCAAAAGGTATTTTAGCGGCAGA
GTCTTTTCTTGACTTGGAGCATCTTTTTTCCAAGGAAAATCAAGAGTTGGTCCGCCACCTCAATCTAGCCTTGCGGGCCC
ACAAGCTCTACAAGAAGGATAAGGACTATGTTGTCCGCCAGGGTGACAAAGAAGCAGAAGTTGTACTTCTGGACCGCGCA
ACCGGCCGTCTGCTGGAAATGACCCGGCTTCAGGGAGGCCAGCACCAGGCCATTGAGGCCAAGGAGCATGTCAAGCTGAC
GGAGGAAACGCGGGCCATGGCTTCCATCACCTATCAGAATCTCTTCCGGCTCTTCCGGAAAATCTCTGGTATGACTGGAA
CCGGCAAGGTGGTGGAGAGCGAGTTTATGGAGACTTACTCCATGTCTGTCATCAAGATCCCGACCAACCAGCCAGTTATT
CGACAGGATTTGCCAGACCAGCTTTATCAGACTCTGCCAGAAAAAGTCTTTGCTTCACTAGACGAGGTCAAGCACTACCA
TGCTCAAGGCAATCCACTCTTGATTTTCACCGGCTCAGTGGAGATGTCAGAGATTTACTCTTCCCTACTGCTGAGAGAAG
GCATCGCCCACAATCTGCTCAATGCCAACAATGCGGCGCGTGAGGCGCAGATCATCGCAGAGTCTGGGCAGAAAGGTGCT
GTGACGGTGGCTACATCCATGGCCGGCCGCGGTACGGATATAAAGTTGGGACCGGGTGTCGCTGATTTGGGTGGTCTCGT
GGTGATTGGTACTGAGCGGATGGAGAACCAGCGGATTGACCTACAGATTCGTGGCCGTTCAGGCCGCCAAGGTGATCCGG
GGATTAGTAAGTTTTTCATCTCGCTAGAGGATGATCTGCTCAGGAAGTGGGGGCCAGATTGGCTCAAGAAGCTCTACAAG
GACTATTCAACTGAAGAAGTTCAGCAGCATCCAGTCCAGCTGGGACAGCGCCGCTTTAGACGCTTAGTAGCTAAGGCCCA
GAGAGCCAGCGAAAGCAGTGCCAAGATGTCCCGTCGGATGACGTTGGAATATGCCCAGTGTATGAAGATTCAGCGGGAGA
TTACCTATGCTGAGCGCAATCGTCTGATTCAAGCTGAAGAGCGGATTGATGAAGAAATCAGCCGTGTCCTCAGTCAGGTC
ATTCATCAGGCGGCCTATGAGCAGTCCTATGAGACGCGAGCTGACCTCTATCGCTTTATTTTAGACCATTTCAGCTATCA
TGCTGAGCGTATTCCTTATGATTTTGATATTTATTCGCCGGAGAAAATTGCAGAGCTCTTGCAGGATATTGCCGAGCAGG
AATTGCAGGCAAAGAAAGCCTATCTCAAGTCTGACAAGCTATTCACCCATTTTCAGCGGGTGTCCGTTCTCAAGGCTATT
GATGAGAACTGGGTCGAGCAGGTGGACTATCTGCAGCAACTCAAGACGGCCTTGAGCGGTCAGCATTTCTCTATGAAAAA
TCCTCTGGTAGAATATTATCAAGAGGCTTACGATGGCTTTGAATATATGAAGGAGCGCATGAAACAGCAGATTGTCAAGA
ATCTTTTGATGAGTGAATTGGCACTCAACCCTAAAGGAGAAGTCATCATGTACTTCCCGTAA

Protein sequence :
MIKNHFQIQRLKKILAKVKSFESEMAGLTDAELRKKTQEFKERLAAGETLDDLLPEAYAVVREADKRVLGMFPYDVQVMG
AIVLHEGNVAEMATGEGKTLTATMPLYLNALSGQGAMLVTTNTYLALRDAQEMGQVYRFLGLTIEAAVVADETENLTPKQ
KRLIYQADIVYTTNSALGFDYLIENLAENKDSQYLSPFNYVIIDEIDSILLDSAQVPLVISGAPRVQSNFYSIMDTFITT
LKEEEDYHYDDEKNEVWLTSKGILAAESFLDLEHLFSKENQELVRHLNLALRAHKLYKKDKDYVVRQGDKEAEVVLLDRA
TGRLLEMTRLQGGQHQAIEAKEHVKLTEETRAMASITYQNLFRLFRKISGMTGTGKVVESEFMETYSMSVIKIPTNQPVI
RQDLPDQLYQTLPEKVFASLDEVKHYHAQGNPLLIFTGSVEMSEIYSSLLLREGIAHNLLNANNAAREAQIIAESGQKGA
VTVATSMAGRGTDIKLGPGVADLGGLVVIGTERMENQRIDLQIRGRSGRQGDPGISKFFISLEDDLLRKWGPDWLKKLYK
DYSTEEVQQHPVQLGQRRFRRLVAKAQRASESSAKMSRRMTLEYAQCMKIQREITYAERNRLIQAEERIDEEISRVLSQV
IHQAAYEQSYETRADLYRFILDHFSYHAERIPYDFDIYSPEKIAELLQDIAEQELQAKKAYLKSDKLFTHFQRVSVLKAI
DENWVEQVDYLQQLKTALSGQHFSMKNPLVEYYQEAYDGFEYMKERMKQQIVKNLLMSELALNPKGEVIMYFP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 3e-176 50