Gene Information

Name : nrdE (SSA_0770)
Accession : YP_001034751.1
Strain : Streptococcus sanguinis SK36
Genome accession: NC_009009
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 749342 - 751501 bp
Length : 2160 bp
Strand : -
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGGGACTCAAACATTTAGAGGATGTGACATACTTCCGACTCAACAACGAAATCAACCGTCCAGTTAATGGTCAGATTAT
GCTTCATAAAGACCAAGAAGCCTTAAAAGCTTTTTTTAAAGAAAACGTTGAGCCAAACACCAAGCAATTTTCTTCTATCA
CAGAAAAAATTAAATATTTAATAGAAGAAAACTATTTGGAAAAGGAATTTATTGAACTTTATTCTCCGGAATATATCGAG
GAGCTGACTGCTTTTATCCATGCTCAAGATTTCAAGTTTAAATCTTTCATGGCTGCTTATAAGTTCTACAACCAGTATGC
ACTGAAGACCAATGATGGTGAATACTATCTGGAAAGCATGGAAGATCGGGTACTCTTCAACGCCCTCTACTTTGCCAACG
GAGATGAAGCCATTGCCAAGGATATTGCCAATGAGATTATCCACCAGCGCTATCAACCGGCGACACCAAGCTTCCTCAAC
GCTGGTCGGGCTCGTCGCGGTGAATTGGTTTCTTGCTTCCTCATCCAAGTAACAGATGACATGAACTCCATCGGTCGCTC
CATCAACTCTGCCCTGCAATTGTCTCGTATCGGAGGCGGGGTCGGTATTTCCCTCAGCAATCTGCGGGAAGCTGGAGCTC
CTATCAAGGGCTATGAAGGTGCTGCATCTGGGGTTGTGCCTGTTATGAAACTCTTTGAGGACAGTTTCTCTTACTCTAAC
CAGCTGGGCCAACGTCAGGGAGCTGGGGTTGTTTACCTCAATGTTTTCCACCCAGATATCATCTCTTTCCTTTCTACCAA
GAAAGAAAACGCCGACGAAAAAGTTCGGGTTAAAACCCTCTCACTCGGCGTCGTCATTCCGGATAAGTTCTACGAATTGG
CGCGTAAAAATGAAGAAATGTACCTCTTCAGCCCATATTCTGTTGAACGCGAGTACGGTGTGCCATTTGCCTACCTCGAC
ATCACTGAAAAATACGATGAATTGGTCGCTAATCCAAATATCACTAAGACTAAGATCAAGGCTCGTGATTTGGAAACAGA
AATTTCTAAACTCCAACAAGAATCTGGCTATCCTTATGTCGTAAACATTGATACGGCCAACCGTTCAAATCCAATTGACG
GTAAAATCGTCATGAGTAACCTTTGCTCTGAAATCCTGCAAGTACAAGAGCCTAGCCTTTTGAATGATGCGCAAGAGTAT
CTTCACCTGGGAACAGATGTATCATGTAACTTAGGCTCTACCAACGTTGTCAACATGATGACTTCGCCTGACTTCGGAAA
ATCCATCCGAACTATGACACGCGCTTTGACCTTTGTCACAGACAGCTCGCACATCACAGCTGTGCCTTCTATCGACAATG
GTAACAGTCTGGCGCATACCTTTGGTCTGGGAGCTATGGGACTGCACAGCTACTTGGCACAGCAGCTGATCGATTATGGA
TCAGCGGAAGCTGTAGAGTTCACTAGCATCTACTTCATGCTCATGAACTACTGGACTTTAGTCGAGTCTAACAATATCGC
TCGCGAACGTGGCGTGACCTTCCATAACTTTGAAAAATCTGACTATGCTAACGGCACTTACTTTGACAAATACCTGACGG
GTGAATTTGTACCTAAGTCTGACCGTGTCAAAGAACTCTTCGCAGGCATCTTTATCCCGTCTCCAGAGGATTGGGCAGAG
TTGCGCGACAAGATCAAGGCTGATGGTCTCTACCACCAAAACCGCTTGGCCGTTGCACCAAATGGCTCTATCAGCTACAT
CAATGACGTTTCTGCTTCAATTCATCCAATTACTCAAAGGATTGAAGAACGTCAAGAAAAGAAAATCGGTAAAATCTACT
ATCCTGCTGCTGGTCTGTCAACTGAGACTATTCCTTACTACACCAGCGCCTATGACATGGATATGCGCAAGGTTATCGAT
GTCTATGCAGCGGCAACCGAGCACGTGGACCAAGGTCTTTCCCTGACTCTCTTTATGCGCAGCGATATCCCTAAAGGCCT
CTACGAATGGAAAAAAGAAAGCAAGCAGACAACCCGCGATCTTTCTATCCTGCGTAACTATGCCTTCAACAAGGGAATCA
AGTCCATCTACTACGTCCGCACCTTTACTGATGATGGCGGCGAAGTAGGTGCCAACCAATGTGAAAGCTGTGTCATCTAA

Protein sequence :
MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDQEALKAFFKENVEPNTKQFSSITEKIKYLIEENYLEKEFIELYSPEYIE
ELTAFIHAQDFKFKSFMAAYKFYNQYALKTNDGEYYLESMEDRVLFNALYFANGDEAIAKDIANEIIHQRYQPATPSFLN
AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGISLSNLREAGAPIKGYEGAASGVVPVMKLFEDSFSYSN
QLGQRQGAGVVYLNVFHPDIISFLSTKKENADEKVRVKTLSLGVVIPDKFYELARKNEEMYLFSPYSVEREYGVPFAYLD
ITEKYDELVANPNITKTKIKARDLETEISKLQQESGYPYVVNIDTANRSNPIDGKIVMSNLCSEILQVQEPSLLNDAQEY
LHLGTDVSCNLGSTNVVNMMTSPDFGKSIRTMTRALTFVTDSSHITAVPSIDNGNSLAHTFGLGAMGLHSYLAQQLIDYG
SAEAVEFTSIYFMLMNYWTLVESNNIARERGVTFHNFEKSDYANGTYFDKYLTGEFVPKSDRVKELFAGIFIPSPEDWAE
LRDKIKADGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETIPYYTSAYDMDMRKVID
VYAAATEHVDQGLSLTLFMRSDIPKGLYEWKKESKQTTRDLSILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 5e-180 54