Gene Information

Name : nrdF (SSA_0768)
Accession : YP_001034749.1
Strain : Streptococcus sanguinis SK36
Genome accession: NC_009009
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 748226 - 749185 bp
Length : 960 bp
Strand : -
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGCAAACTTACTATAAAGCCATTAACTGGAACGCTATTGAAGATGTCATCGATAAGTCCACCTGGGAAAAACTGACCGA
GCAATTCTGGCTGGATACGCGGATTCCCCTATCCAATGACCTGGATGACTGGAGAAAGCTGTCTCACAAGGAAAAAGATC
TGGTCGGCAAAGTCTTCGGCGGCTTGACCCTGCTGGATACCCTCCAGTCTGAGTCTGGTGTGGATGCCCTGCGCAAGGAT
GTCCGCACTGCCCACGAAGAAGCTGTCTTCAACAACATTCAATTTATGGAATCCGTTCACGCCAAGTCCTACTCTTCTAT
CTTTTCTACGCTCAATACCAAGTCAGAAATTGATGAAATCTTTGCTTGGACCAACACCAATCCATACCTGCAAAAGAAAG
CTGAGATTATCAACGAGATTTACCTGAACGGTACAGCTCTGGAAAAGAAAATAGCCAGCGTTTTCTTGGAAACCTTCCTC
TTCTACTCTGGTTTCTTTACTCCGCTCTACTATCTGGGCAACAACAAACTGGCTAACGTTGCTGAGATTATCAAGCTGAT
TATCCGTGATGAATCTGTCCATGGAACCTATATCGGCTACAAGTTCCAGCTAGCTTTTAACGAGCTGCCAGAAGACGAGC
AAGAAAAACTCAAAGAATGGATGTATGACCTGCTCTACACCCTCTATGAAAATGAAGAAGGCTATACTGAAAGCCTGTAT
GACACAGTCGGCTGGACCGAAGAGGTCAAGACCTTCCTGCGCTACAATGCCAACAAGGCTCTGATGAATCTGGGACAGGA
TCCCCTCTTCCCAGACTCAGCGGACGATGTCAATCCTATCGTTATGAACGGTATCTCAACCGGTACTTCCAACCATGACT
TCTTCTCCCAAGTGGGTAACGGCTACCTGCTGGGCGAAGTTGAAGCCATGCAGGATGACGACTATAATTACGGTTTATAA

Protein sequence :
MQTYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRKLSHKEKDLVGKVFGGLTLLDTLQSESGVDALRKD
VRTAHEEAVFNNIQFMESVHAKSYSSIFSTLNTKSEIDEIFAWTNTNPYLQKKAEIINEIYLNGTALEKKIASVFLETFL
FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLAFNELPEDEQEKLKEWMYDLLYTLYENEEGYTESLY
DTVGWTEEVKTFLRYNANKALMNLGQDPLFPDSADDVNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 8e-75 50